Results 191 to 200 of about 362,061 (261)

Artificial Cell Catalysts for Biotransformation: Design Principles and Process Integration

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Artificial cell catalysts are emerging as programmable biocatalytic platforms for sustainable molecular conversion. By reconstituting enzymes and functional modules within synthetic compartments, they combine the selectivity of biological catalysis with the design flexibility of synthetic materials.
Iori Kobayashi, Shogo Yoshimoto, Katsutoshi Hori   +2 more
wiley   +1 more source

Biocatalytic designs for the conversion of renewable glycerol into glycerol carbonate as a value-added product

Open Chemistry, 2014
Tudorache Madalina, Ghemes George, Nae Andreea, Matei Elena, Mercioniu Ionel, Kemnitz Erhard, Ritter Benjamin, Coman Simona, Parvulescu Vasile   +8 more
doaj   +1 more source

Species Dynamics and Gene Expression in Algal Polycultures Under Mixotrophic Cultivation in Outdoor Pilot‐Scale Nordic Conditions

Biotechnology and Bioengineering, EarlyView.
These results demonstrate that mixotrophic conditions drive both microbial community shifts and metabolic reprogramming, underscoring the importance of cultivation strategy and polyculture selection for targeted applications such as nutrient recovery and bioproduct generation.
Quyen Nham, Hanna Farnelid, Catherine Legrand, Elin Lindehoff   +3 more
wiley   +1 more source

Glycerol carbonate: a novel biosolvent with strong ionizing and dissociating powers. [PDF]

ScientificWorldJournal, 2012
Ou G, He B, Li X, Lei J.
europepmc   +1 more source

Quantitative Partitioning of Photoautotrophic and Photoheterotrophic Contributions During Mixotrophic Growth of Scenedesmus obliquus

Biotechnology and Bioengineering, EarlyView.
Carbon and oxygen fluxes during photoautotrophic, photoheterotrophic and mixotrophic growth of Scenedesmus obliquus. ABSTRACT Mixotrophic growth of microalgae involves the simultaneous assimilation of inorganic and organic carbon sources, but the quantitative contributions of photoautotrophic and photoheterotrophic metabolisms remain poorly resolved ...
Solène Jahan, Thibault Combroux, Samy Kemel, Hélène Marec, Mariana Titica, Howard Fallowfield, Jérémy Pruvost, Guillaume Cogne   +7 more
wiley   +1 more source

Combinatorial Metabolic Engineering of Alkane Biosynthesis in the Osmotolerant Yeast Debaryomyces hansenii CBS 767

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Debaryomyces hansenii is a yeast with diverse potential applications like producing oleochemicals from biomass. Yet, combinatorial metabolic engineering in D. hansenii is limited because, like many nonconventional organisms, key genomic data and genetic elements are missing. Here, we report phenotypic characterization, genomic integration loci,
Zekun Li, Nilesh Kumar Sharma, Sarah Weintraub, Eric Young   +3 more
wiley   +1 more source

Cell and Gene Therapies Manufacturing Challenges and Integrated Good Manufacturing Practices Solutions: A Lifecycle Perspective

Biotechnology and Bioengineering, EarlyView.
Lifecycle perspective on cell and gene therapy manufacturing challenges and enabling GMP solutions. ABSTRACT Cell and gene therapies (CGTs) are revolutionizing modern medicine; however, making these advanced medicines scalable and readily available to commercial manufacturers worldwide is a major challenge. The number of approved CGT products continues
Rajath Samaga, Udisha Singh, Sachin Dattram Pawar   +2 more
wiley   +1 more source

Synthesis of poly(1,2-glycerol carbonate)-paclitaxel conjugates and their utility as a single high-dose replacement for multi-dose treatment regimens in peritoneal cancer. [PDF]

Chem Sci, 2017
Ekladious I, Liu R, Zhang H, Foil DH, Todd DA, Graf TN, Padera RF, Oberlies NH, Colson YL, Grinstaff MW.   +9 more
europepmc   +1 more source

Reducing Cooling Costs for Sustainable Food Biomanufacturing With Thermotolerant Cupriavidus necator H16 Mutant

Biotechnology and Bioengineering, EarlyView.
With a thermotolerant C. necator mutant the SCP production costs can be decreased by $0.98/kg. ABSTRACT Autotrophic CO2 conversion to Single Cell Protein (SCP) using H2 and O2 is gaining commercial traction for food and feed production. Cupriavidus necator H16 is a key chassis organism for this “knallgas” fermentation, but industrial operation is ...
Lars Puiman, James Kemp Heffernan, Esteban Marcellin   +2 more
wiley   +1 more source

Autonomous Control of Gene Expression Using Endogenous Transcription Signals

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Autonomous cell‐based control of heterologous gene expression can simplify batch‐culture bioprocessing by eliminating external monitoring and extrinsic control of culture conditions. Existing approaches use auto‐induction media, synthetic cell‐cell communication systems, or application‐specific biosensors.
Pakpoom Subsoontorn, Drew Endy, Olivier Borkowski   +2 more
wiley   +1 more source