Results 271 to 280 of about 96,589 (331)

NADH‐Reductive Stress Induced by Dihydrolipoamide Dehydrogenase Activation Contributes to Cuproptosis

open access: yesAdvanced Science, EarlyView.
This study demonstrates a cuproptosis mechanism involving nicotinamide adenine dinucleotide (NADH)‐reductive stress in neural cells. Copper activates dihydrolipoamide dehydrogenase under mitochondrial pH, accumulating NADH. Copper also induces mitochondrial permeability transition pore opening, facilitating NADH translocation to the cytosol and ...
Si‐Yi Zhang   +3 more
wiley   +1 more source

Electronic Modulation of K⁺‐Intercalated Polymeric Carbon Nitride via ─C≡N/─OH Functionalization for Efficient Photocatalytic H2O2 Production

open access: yesAdvanced Science, EarlyView.
K+ is successfully embedded in the PCN interlayers via a high‐temperature polymerization. The incorporation of K+ perturbs the local electronic structure via interaction with nitrogen lone pairs, narrowing the PCN bandgap, which exhibits superior photocatalytic performance, achieving a high H2O2 generation rate both in situ and under sunlight ...
Qingquan Xue   +8 more
wiley   +1 more source

Structural Basis of the Membrane Association by the Conserved RocS Membrane‐Targeting Sequence in Streptococcus

open access: yesAdvanced Science, EarlyView.
Chromosome segregation in Streptococcus pneumoniae depends on RocS, a bitopic protein whose membrane‐anchoring mechanisms were unclear. Using NMR and AFM, this study reveals that the widely conserved RocS anchor binds to membranes via a conserved kink‐helix motif which inserts into lipid nanodomains.
Ana Álvarez‐Mena   +11 more
wiley   +1 more source

⁠Reversible C─H Insertion in Bulky Unsaturated NHCs: A Carbon-Based Analogue of Oxidative Addition/Reductive Elimination. [PDF]

open access: yesChemistry
Sánchez A   +8 more
europepmc   +1 more source

Soft, Flexible, and Stretchable Platforms for Tissue‐Interfaced Bioelectronics

open access: yesAdvanced Science, EarlyView.
Bio‐integrated electronics provide mechanically compliant and stable interfaces with soft biological tissues. Representative applications include neural interfaces, wet‐organadhesive electronics, and skin‐interfaced devices. E represents Young´s modulus and ε represents strain.
Kento Yamagishi   +3 more
wiley   +1 more source

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