Results 61 to 70 of about 16,833 (197)

TO COMPARE THE EFFICACY OF INTERNAL SPHINCTEROTOMY WITH TOPICAL 0.2% GLYCERYL TRINITRATE OINTMENT AFTER HEMORRHOIDECTOMY FOR PAIN RELIEF

Pakistan Armed Forces Medical Journal, 2015
Objective: To compare the efficacy of internal sphincterotomy with topical 0.2% glyceryl trinitrate ointment after hemorrhoidectomy for pain relief. Study Design: Randomized controlled trial.
Adnan Ali, Bilal Umair, Maqsood Ahmed, Hafiz Khalid Perwaiz   +3 more
doaj   +2 more sources

Vitamin B3 (Nicotinamide) Supplementation in Primary and Scleroderma‐Related Raynaud Phenomenon

ACR Open Rheumatology, Volume 8, Issue 8, August 2026.
Objective The aim of this study was to explore if vitamin B3 (nicotinamide) supplementation is a safe and effective adjunctive therapy for patients with primary Raynaud phenomenon (RP) and scleroderma‐related RP. The effect of nicotinamide supplementation in human patients with RP has not been studied before.
Mogeshni Govender, Natalie Tomson, Johnny Fang, Mohamed Bakry, Raymond Liu, Kathleen Morrisroe, Ross Penglase, Kokum Dissanayake, Ted Tsai   +8 more
wiley   +1 more source

Addressing ‘hard‐to‐fund’ research questions in bowel research: Exploring the role of decision architecture randomised trials

Colorectal Disease, Volume 28, Issue 8, August 2026.
Abstract Patients and health professionals face difficult decisions every day when choosing between standard‐of‐care treatments for the same disease. In bowel disease, some treatments are used interchangeably, but a lack of evidence may exist as to whether one is more effective than another. Randomised controlled trials provide robust evidence in these
Stephen J. Chapman, Carly Bisset, Hayley Fowler, Alice Murray, Jessica Banks, Judit Kovacs, Jim Tiernan, Julie Cornish, Susan Moug, Dale Vimalachandran, James H. Flory, Andrew Vickers, Clare Relton   +12 more
wiley   +1 more source

A comparative study of dexmedetomidine, magnesium sulphate, or glyceryl trinitrate in deliberate hypotension during functional endoscopic sinus surgery

, 2015
Context Induced hypotension to minimize bleeding during functional endoscopic sinus surgery (FESS) is of vital importance to the surgeon and anesthetist to decrease the risk of complications as well as procedural failure.
Omyma Khalifa, O. Awad
semanticscholar   +1 more source

Iatrogenic Left Main Coronary Artery Dissection With Retrograde Aortic Extension During Complex Percutaneous Coronary Intervention in a Left‐Dominant System: A Case Report

Clinical Case Reports, Volume 14, Issue 7, July 2026.
Clinical course of catheter‐induced left main coronary artery dissection during complex percutaneous coronary intervention (PCI) for heavily calcified left main bifurcation disease. Following iatrogenic ostial left main dissection with limited retrograde extension into the aortic root, immediate haemodynamic stabilisation and bailout PCI were performed
Ghulam Abbas Shaikh, Samina Yaqoob, Ali Aamir, Zahra Anas, Aniqa Dejwani, Atiqullah Sadaqat   +5 more
wiley   +1 more source

COMPARISON OF LATERAL INTERNAL SPHINCTEROTOMY WITH 0.2% GLYCERYL TRINITRATE IN THE MANAGEMENT OF CHRONIC ANAL FISSURE

Pakistan Armed Forces Medical Journal, 2011
Objective: To compare the effectiveness of topical Glyceryl trinitrate Ointment with Lateral internal Sphincterotomy in terms of relief of pain, healing of fissure and absence of bleeding over a period of two months. Study Design: Randomized controlled
Habib Ur Rehman, Mohammad Pervez
doaj   +2 more sources

Non‐invasive pressure–volume loop analysis in left ventricular load manipulation

Clinical Physiology and Functional Imaging, Volume 46, Issue 4, July 2026.
Abstract Background Clinical monitoring of patients with heart failure or cardiomyopathy is facilitated by detailed assessment of cardiac loading conditions. Specifically, alterations in preload and afterload may unmask pathology through effects on ventricular pressure–volume (PV) relations. Therefore, the aim was to assess non‐invasive PV loops during
Karin Pola, Charlotte Burup Kristensen, William D. Watson, Peregrine G. Green, Betty Raman, Stefan Neubauer, Oliver J. Rider, Christian Hassager, Rasmus Møgelvang, Per M. Arvidsson   +9 more
wiley   +1 more source

Randomised Comparison of the Effect of 0.2% Glyceryl Trinitrate and 0.5% Topical Nifedipine in Acute Anal Fissure Treatment

Turkish Journal of Colorectal Disease, 2020
Aim:This prospective clinical trial study aimed to compare the effects of 0.2% glyceryl trinitrate (GTN) and 0.5% topical nifedipine (ND) on acute anal fissure treatment and recurrence prevention.Method:The study included 100 patients who were diagnosed ...
Ozan Akıncı, Sangar M Faroq Abdulrahman, Özlem Güngör, Necip Serdar Yüceyar, Asiye Perek, Murat Süphan Ertürk   +5 more
doaj   +1 more source

Blood Pressure Control With Clevidipine Is Associated With Hematoma Volume Reduction in Acute Hypertensive Intracerebral Hemorrhage: A Single‐Center Prospective Cohort Study

European Journal of Neurology, Volume 33, Issue 7, July 2026.
In this prospective cohort study of 64 patients with hypertensive intracerebral hemorrhage, intravenous clevidipine administration achieved rapid blood pressure control and was associated with greater 24‐h hematoma volume reduction compared with standard antihypertensive therapy (14.7% vs. 4.5% in controls).
Angeliki‐Erato Sterpi, Aikaterini Theodorou, Anna Keramida, Georgia Papagiannopoulou, Eleni Bakola, Maria Chondrogianni, Maria‐Ioanna Stefanou, Klearchos Psychogios, Odysseas Kargiotis, Efstathios Manios, Apostolos Safouris, Lina Palaiodimou, Georgios Tsivgoulis   +12 more
wiley   +1 more source

Inflammation induced by snake venoms optimizes envenomation

The Journal of Physiology, Volume 604, Issue 14, Page 5831-5852, 15 July 2026.
Abstract figure legend Schematic illustrating mechanisms underlying direct vascular absorption and subsequent movement of venom toxins into the tissues consequent to snakebite. A, snakebite into prey deposits venom toxins into the tissue interstitium, with the venom then causing acute inflammation primarily in venules.
Dirk F. van Helden, Neil Spratt, Peter J. Dosen, Sally A. McFadden, John Holdsworth, Daniel J Beard, Kirsten Coupland, Phillip Jobling, Todd A. Hardy, Derek R. Laver   +9 more
wiley   +1 more source