Results 291 to 300 of about 1,006,170 (352)

Elevated Apolipoprotein E Expression in Hippocampal Microglia Drives Temporal Lobe Epilepsy Progression

Advanced Science, EarlyView.
In temporal lobe epilepsy, hippocampal APOE is markedly upregulated predominantly in microglia. APOE overexpression in microglia drives TLR4 and cGAS/STING‐dependent neuroinflammation, engages bidirectional crosstalk with neurons and astrocytes, increases neuronal excitability, and perturbs hippocampal lipid metabolism. These findings suggest that APOE‐
Jianwei Shi, Zesheng Li, Xin Sun, Yanfeng Yang, Yumin Luo, Ziang Song, Hengxin Dong, Lei Jin, Jing Xie, Yongzhi Shan, Guoguang Zhao   +10 more
wiley   +1 more source

A Functional Photorespiratory Cycle Is Essential for Light-Dependent Stomata Opening in Epidermal Peels of Arabidopsis thaliana. [PDF]

Physiol Plant
Mortezazadeh A, Hodges M, Jossier M.
europepmc   +1 more source

Interplay between malic enzyme 2, de novo serine synthesis, and the malate-aspartate shuttle drives metabolic adaptation in triple-negative breast cancer. [PDF]

Cancer Metab
Jeon JH, Slayton MD, Krinkel B, Animasahun O, Shankaran A, Wuchu F, Nenwani M, Farah Z, Burke J, Achreja A, Nilaj B, Kohagen K, Eu YH, Rosenfeld A, Collard M, Bao L, Cheng X, Kleer C, Squire C, Loomes K, Nagrath D, Merajver SD.   +21 more
europepmc   +1 more source

Impact of Bile Acid Amidation on In Silico Farnesoid X Receptor Dynamics. [PDF]

J Phys Chem B
Eisert-Sasse RK, Biswas A, Okafor CD.
europepmc   +1 more source

Design and Manufacturing of Piezoelectric Biomaterials for Bioelectronics and Biomedical Applications. [PDF]

Chem Rev
Zhang Z, Wang Z, Li X, Zheng Y, Yang Z.
europepmc   +1 more source

Dynamics and Interplay of the Binding Pockets in the Glycine Receptor. [PDF]

J Chem Inf Model
Xue G, Clark JA, Kemble-Diaz C, Crnjar A, Molteni C.   +4 more
europepmc   +1 more source

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Glycine

2021
Evaluation of perennial Glycine species for resistance to P. penetrans The Bartlett test for homogeneity of variance was significant (P
Han, Jaeyeong, Locke, Steven P, Herman, Theresa K, Schroeder, Nathan E, Hartman, Glen L   +4 more
openaire   +1 more source

The Absorption of Glycine and Glycine Oligopeptides by the Rat

Clinical Science, 1970
1. Samples of portal venous and femoral arterial plasma and mesenteric lymph were collected from unanaesthetized rats before and during the intra-duodenal infusion of high concentrations (100 mmol/l) of glycine or glycine oligopeptides (up to and including tetraglycine). 2. There was a marked increase in the concentration of free glycine,
T. J. Peters, M. T. MacMahon
openaire   +3 more sources

Glycine Encephalopathy

Neuropediatrics, 1979
4 cases of nonketotic hyperglycinemia (glycine encephalopathy), one with autopsy, are presented and the literature on 61 cases is reviewed. Major clinical signs include early hypotonia, lethargy and erratic and massive myoclonias with respiratory distrubances, starting during the first days of life after a symptom-free interval.
DALLA BERNARDINA, Bernardo, J. Aicardi, F. Goutieres, P. Plouin   +3 more
openaire   +3 more sources