Results 291 to 300 of about 1,021,445 (339)
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The Absorption of Glycine and Glycine Oligopeptides by the Rat
Clinical Science, 19701. Samples of portal venous and femoral arterial plasma and mesenteric lymph were collected from unanaesthetized rats before and during the intra-duodenal infusion of high concentrations (100 mmol/l) of glycine or glycine oligopeptides (up to and including tetraglycine). 2. There was a marked increase in the concentration of free glycine,
T J, Peters, M T, MacMahon
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Pharmacology & Therapeutics, 1997
The inhibitory glycine receptor (GlyR) is a member of the ligand-gated ion channel receptor superfamily. The GlyR comprises a pentameric complex that forms a chloride-selective transmembrane channel, which is predominantly expressed in the spinal cord and brain stem. We review the pharmacological and physiological properties of the GlyR and relate this
Rajendra, S, Lynch, JW, Schofield, PR
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The inhibitory glycine receptor (GlyR) is a member of the ligand-gated ion channel receptor superfamily. The GlyR comprises a pentameric complex that forms a chloride-selective transmembrane channel, which is predominantly expressed in the spinal cord and brain stem. We review the pharmacological and physiological properties of the GlyR and relate this
Rajendra, S, Lynch, JW, Schofield, PR
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Dependence of glycine conjugation on availability of glycine: role of the glycine cleavage system
Xenobiotica, 19931. Glycine conjugation of benzoic acid was investigated in anaesthetized rats by measuring the disappearance of benzoate from blood, and the appearance of benzoylglycine in blood and urine. 2. Administration of glycine (1-10 mmol/kg,i.v.) increased the capacity of benzoylglycine formation in a dose-dependent fashion, with a maximal rate (8.1 mumol/kg ...
Z, Gregus +3 more
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Canadian Journal of Biochemistry and Physiology, 1963
The supernatant fraction of liver homogenate brings about the methylation of glycine by S-adenosylmethionine. The secondary amine formed in the reaction appears to be sarcosine. This conclusion is based on (I) the stoichiometry of the reaction, and (II) radioautography of chromatograms of the incubation products. The enzyme, glycine N-methyltransferase,
J, BLUMENSTEIN, G R, WILLIAMS
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The supernatant fraction of liver homogenate brings about the methylation of glycine by S-adenosylmethionine. The secondary amine formed in the reaction appears to be sarcosine. This conclusion is based on (I) the stoichiometry of the reaction, and (II) radioautography of chromatograms of the incubation products. The enzyme, glycine N-methyltransferase,
J, BLUMENSTEIN, G R, WILLIAMS
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Gas Phase Conformations of Tetrapeptide Glycine-Phenylalanine-Glycine-Glycine
Chinese Journal of Chemical Physics, 2012Systematic search of the potential energy surface of tetrapeptide glycine-phenylalanine-glycine-glycine (GFGG) in gas phase is conducted by a combination of PM3, HF and BHandHLYP methods. The conformational search method is described in detail. The relative electronic energies, zero point vibrational energies, dipole moments, rotational constants ...
Hui-bin Chen +3 more
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Glycine transporters (glycine transporter 1 and glycine transporter 2) are expressed in retina
NeuroReport, 2008The amino acid glycine is an inhibitory neurotransmitter in the spinal cord, brain stem, and vertebrate retina. The effective synaptic concentrations of glycine are regulated by at least two transporters: glycine transporter 1 and glycine transporter 2.
Ma Teresa, Peña-Rangel +3 more
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1954
Publisher Summary This chapter discusses that in the biosynthesis of many nitrogenous substances glycine occupies a key position in amino acid metabolism. The great metabolic activity of glycine is reflected also by the diversity of its reactions, which involve all three positions of the molecule, but particularly the methylene and amino groups ...
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Publisher Summary This chapter discusses that in the biosynthesis of many nitrogenous substances glycine occupies a key position in amino acid metabolism. The great metabolic activity of glycine is reflected also by the diversity of its reactions, which involve all three positions of the molecule, but particularly the methylene and amino groups ...
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Glycine and transurethral resection
Anaesthesia, 1986Summary Fifty patients undergoing transurethral resection of the prostate were studied for evidence of glycine absorption and haemodilution. Plasma glycine levels increased substantially in nine patients and, in five, calculated irrigant, fluid absorption ranged from 619–1582 ml; another patient had absorbed 1360 ml fluid with only a ...
J P, Alexander +2 more
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