Results 311 to 320 of about 969,294 (383)

Highly Stretchable, Self‐Healable, and Conductive Gelatin Methacryloyl Hydrogel for Long‐Lasting Wearable Tactile Sensors

Advanced Science, EarlyView.
Gelatin methacryloyl hydrogel, which possesses high stretchability, tensile strength, toughness, and autonomous self‐healing capability at room temperature, is developed through the introduction of interpenetrating networks, hierarchical hydrogen bonds (weak and strong H‐bonds), and borate ester bonds.
Zhikang Li, Bin Wang, Jijian Lu, Yumeng Xue, Jiaxiang Wang, Boqing Jia, Gengyu Han, Yihe Zhao, Muhammad Afzal Khan Qureshi, Lan Yu, Kang Zhao, Min Li, Ping Yang, Dejiang Lu, Libo Zhao   +14 more
wiley   +1 more source

The precise molecular diagnosis of novel <i>GLDC</i> compound heterozygous variants highlights the benefits for a Chinese family with nonketotic hyperglycinemia. [PDF]

Mol Genet Metab Rep
Yuan F, Song X, Yin R, Lan X, Sun J, Tang X, Xu W, Hu S, Xiao M, Zhang H, Weng W, Zhang Y, Wu S.   +12 more
europepmc   +1 more source

Loss of STARD7 Triggers Metabolic Reprogramming and Cell Cycle Arrest in Breast Cancer

Advanced Science, EarlyView.
Breast cancer cells undergo metabolic and transcriptomic reprogramming to support aberrant cell proliferation. Their mitochondria rely on the transfer of phosphatidylcholine from the endoplasmic reticulum to their membranes by STARD7, a candidate upregulated in breast cancer, to be functional.
Ewelina Dondajewska, Paula Allepuz‐Fuster, Chloé Maurizy, Alexandre Hego, Sandra Ormenese, Quentin Lion, Arnaud Blomme, Pierre Close, Arnaud Lavergne, Latifa Karim, Marc Thiry, Ivan Nemazanyy, Roopesh Krishnankutty, Jair Marques Jr, Alex von Kriegsheim, Nathaniel F. Henneman, Ganna Panasyuk, Kateryna Shostak, Alain Chariot   +18 more
wiley   +1 more source

Nontargeted and targeted metabolic profile of metabolic syndrome patients: a study based on Yi and Han populations in Yunnan. [PDF]

Front Endocrinol (Lausanne)
Ji Y, Guo N, Li W, He X, Dao M, Meng N, Zhou D, Tian H, Pi T, Zong X, Xiong Q, Wang Z, Jin X.   +12 more
europepmc   +1 more source

Structural Variations Associated with Adaptation and Coat Color in Qinghai‐Tibetan Plateau Cattle

Advanced Science, EarlyView.
This study reveals the landscape of structural variants in Qinghai‐Tibetan Plateau cattle through long‐read sequencing. Discoveries include metabolic and oxygen‐regulation gene variants, along with a 2‐Mb KIT‐containing inversion and translocations responsible for cattle gray coat. These findings highlight the significant role of structural variants in
Xiaoting Xia, Fuwen Wang, Xiaoyu Luo, Shuang Li, Yang Lyu, Yining Zheng, Zhijie Ma, Kaixing Qu, Rende Song, Jianyong Liu, Jicai Zhang, Basang Wangdui, Basang Zhuzha, Suolang Quji, Li Zhao, Silang Wangmu, Ciren Luobu, Nima Cangjue, Danzeng Luosang, Suolang Sizhu, Haijian Cheng, Ruizhe Li, Zhipeng Wu, Ruihua Dang, Yongzhen Huang, Xianyong Lan, Luohao Xu, Haifei Hu, WaiYee Low, Zhuqing Zheng, Yu Wang, Yuanpeng Gao, Lu Deng, Johannes A. Lenstra, Jianlin Han, Xueyi Yang, Wenfa Lyu, Bizhi Huang, Chuzhao Lei, Ningbo Chen   +39 more
wiley   +1 more source

Functionalization of Polycaprolactone 3D Scaffolds with Hyaluronic Acid Glycine-Peptide Conjugates and Endothelial Cell Adhesion. [PDF]

Biomacromolecules
Mohan T, Gürer F, Bračič D, Lackner F, Nagaraj C, Maver U, Gradišnik L, Finšgar M, Kargl R, Kleinschek KS.   +9 more
europepmc   +1 more source

Electrochemical‐Genetic Programming of Protein‐Based Magnetic Soft Robots for Active Drug Delivery

Advanced Science, EarlyView.
This manuscript presents a protein‐based soft robot for active drug delivery. Stimuli‐responsive protein is rationally designed and processed into the substrate of robots. Superparamagnetic Fe3O4 nanoparticles are patterned on the substrate using an electrochemical method, enabling the robot to respond to external physical fields.
Hang Zhao, Bo Yu, Dingyi Yu, Ting Ji, Kexin Nie, Jingyi Tian, Xinchen Shen, Kaiyue Zhang, Junhan Ou, Xinyi Yang, Dongfang Xiao, Qi Zhou, Wenwen Huang   +12 more
wiley   +1 more source

SUMOylation is a Translatable Target in Hypoxic MNPs Regulating Retinal Vasculopathy

Advanced Science, EarlyView.
During ischemic retinopathy/retinal vasculopathy, UBC9‐mediated SUMOylation in retinal macrophages enhances their pro‐angiogenic capacity via hypoxia‐induced SUMOylation of FUS at K327/K502. This modification suppresses FUS binding to the Vegfa mRNA 3’UTR, stabilizing transcripts and facilitating VEGFA production. Targeting UBC9 inhibition can serve as
Zheng Zhong, Guangyu Liang, Huimin Yu, Jiaqi Li, Ruohong Wang, Xiaohong Ma, Ziqing Zhou, Yin Zhao, Fei Sun, Xufang Sun   +9 more
wiley   +1 more source

Serum Metabolite Profile in Progressive Versus Nonprogressive Alcohol-Related Liver Disease: A Cross-Sectional Metabolomics Study. [PDF]

Liver Int
Puhakka E, Ahmed H, Haikonen R, Leclercq S, Hanhineva K, Maccioni L, Amadieu C, Lehtonen M, Männistö V, Rysä J, Stärkel P, Kärkkäinen O.   +11 more
europepmc   +1 more source

Bioinspired Claw‐Engaged Adhesive Microparticles Armed with γGC Alleviate Ulcerative Colitis via Targeted Suppression of Macrophage Ferroptosis

Advanced Science, EarlyView.
γGC deficiency in ulcerative colitis drives macrophage ferroptosis‐mediated inflammation. Claw‐engaged microparticles armed with γGC (γGC‐MPs) enhance lesion targeting, promoting localized γGC release and tissue uptake. On the cover, Monkey King (Macrophages) was bound by the Immortal‐Binding Rope and subsequently sealed beneath the Five‐Fingered ...
Rong Wang, Jianwei Zhu, Jinyi Zhou, Jinyang Li, Min Wang, Yuqi Wu, Danshan Zhao, Xiancheng Chen, Xiaoyuan Chen, Yuetong Wang, Jianhua Zou   +10 more
wiley   +1 more source