Results 151 to 160 of about 14,852,730 (303)

Apigenin Protects Hypertensive Intracerebral Hemorrhage by Regulating Trx1 Through Binding to PRDX2

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Intracerebral hemorrhage (ICH) remains the most severe stroke subtype with high mortality and disability rates. Although apigenin has shown cerebroprotective potential in preclinical studies, its mechanism of action, particularly in hypertensive ICH, remains poorly understood.
Hao‐chen Xu   +6 more
wiley   +1 more source

Herbal Therapeutics in Osteoporosis: Mechanisms, Evidence, and Translational Potential

open access: yesPhytotherapy Research, EarlyView.
Schematic overview of bone remodeling dysregulation in osteoporosis and the multi‐target protective role of herbal therapeutics. ABSTRACT Osteoporosis is a chronic bone disease marked by reduced density and increased fracture risk. Current treatments face limitations in safety, efficacy, and long‐term adherence, prompting interest in alternative ...
Elnaz Vafadar Moradi   +5 more
wiley   +1 more source

Rapid and Efficient Affinity Isolation of Engineered Extracellular Vesicles Encapsulating Functional Proteins via Internal Twin‐Strep Tetraspanin Tagging

open access: yesSmall, EarlyView.
Structure‐guided internal twin‐Strep tagging of the tetraspanins CD63 or CD9 enables rapid and efficient antibody‐free affinity isolation of engineered extracellular vesicles (EVs) using Strep technology while allowing luminal protein loading. The approach removes over 96% of contaminants, separates tagged EVs from coexisting viral particles, and ...
Minh‐Tu Pham   +14 more
wiley   +1 more source

Self‐Assembling Gemini‐Type Amphiphiles From Helix‐Loop‐Helix Peptides

open access: yesSmall, EarlyView.
Peptide particles are formed through self‐assembly of amphiphilic helix‐loop‐helix peptides. Depending on the preparation method, two different particle morphologies can be obtained: nanospheres or nanodiscs with α‐helical or β‐sheet structure of the monomers, respectively.
Thomas Heim   +7 more
wiley   +1 more source

Cytogenotoxic and Molecular Assessment of Pyrethrins on Non‐Target Allium cepa Roots

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT The pyrethrins, which form a part of naturally occurring insecticidal chemicals derived from chrysanthemum flowers, not only provide rapid knockdown of a broad spectrum of insect pests but are also widely used in integrated pest management due to a generally favorable safety profile, largely attributed to low mammalian toxicity.
Yudum Yeltekin Uğur   +2 more
wiley   +1 more source

Quantitative trait loci analysis identifying novel genomic regions for off-target dicamba tolerance in soybean [Glycine max (L.) Merr.]. [PDF]

open access: yesBMC Plant Biol
Lee D   +12 more
europepmc   +1 more source

Bioaccessibility of Metal(loid)s From Anthropogenic Contamination in Dry Riverbed Sediments in the Cartagena–La Unión Mining District (Murcia, SE Spain): Implications for Human Health Risk Assessment

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT This study assessed the contamination levels, bioaccessibility, and potential health risks of As, Cd, Cu, Pb, and Zn in sediments from three dry riverbeds (El Beal‐EB, Las Matildes‐LM, and Ponce‐PN) impacted by historical mining activities in the Cartagena‐La Unión Mining District.
José Gregorio Cuevas   +5 more
wiley   +1 more source

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