Results 171 to 180 of about 14,852,730 (303)

CRISPR/Cas9 editing of β-Conglycinin subunits reduces IgE binding in soybean [Glycine max (L.) Merr.]. [PDF]

BMC Plant Biol
Park HR, Park S, Jun JM, Shin YJ, Hwang Y, Jeong KY, Kim MY, Kim ST, Park S, Yoo YH, Lee E, Park G, Kim SG, Park SK.   +13 more
europepmc   +1 more source

The c‐Src inhibitor eCF506 diminishes opioid tolerance and reduces β‐arrestin2 recruitment

British Journal of Pharmacology, EarlyView.
Morphine activation of μ receptors causes tolerance through c‐Src activation and β‐arrestin2 recruitment. c‐Src inhibition or degradation reduces β‐arrestin2 recruitment, μ receptor endocytosis, while causing receptor upregulation, all likely contributing to reduced morphine tolerance.
Samuel Singleton, Fraser Nunn, Erika Lace, Álvaro Lorente‐Macías, Rachel Toth, Asier Unciti‐Broceta, Tim G. Hales   +6 more
wiley   +1 more source

The synergistic effect of salt-tolerant Stutzerimonas stutzeri and arbuscular mycorrhizal fungi alleviates salinity stress in soybean (Glycine max, L.). [PDF]

World J Microbiol Biotechnol
El-Sawah AM, Zaki RM, Ashour EH, Afify AH.   +3 more
europepmc   +1 more source

Sequence of a Soybean (Glycine max L.) Phosphoenolpyruvate Carboxylase cDNA [PDF]

Plant Physiology, 1993
A, Vazquez-Tello, R F, Whittier, T, Kawasaki, T, Sugimoto, Y, Kawamura, D, Shibata   +5 more
openaire   +2 more sources

Interaction with NEGR1 affects mGlu5 cell signalling and the neuroprotection induced by the positive allosteric modulator VU0409551

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose The metabotropic glutamate receptor mGlu5 plays an important role in neuronal survival and synaptic plasticity. We and others have shown that mGlu5 positive allosteric modulators (PAMs) are biased agonists, triggering the activation of neuroprotective pathways and promoting neuronal survival. As mGlu5 biased pharmacology
Jennifer D. S. Guimaraes, Toniana G. Carvalho, Luan A. Pereira, Emanuele G. Silva, Esther M. A. Maciel, Gabriella P. Torres, Thiago Assis, Pablo L. Cardozo, Joao P. P. de Almeida, Nathalia C. Silva, Francesca Pischedda, Giovanni Piccoli, Luciene B. Vieira, Juliana Alves‐Silva, Fabiola M. Ribeiro   +14 more
wiley   +1 more source

Dapagliflozin Alters Plasma Metabolome in Patients With Type 1 Diabetes During Ketosis

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Use of sodium‐glucose cotransporter 2 inhibitors (SGLT2i) in patients with type 1 diabetes (T1D) is limited by increased risk of ketoacidosis. We aimed to determine metabolic pathways affected by SGLT2i treatment in adults with T1D during ketosis induced by insulin withdrawal.
Rosa Yang, Kevin Cho, Max C. Petersen, Kai E. Jones, Gary J. Patti, Janet B. McGill, Samantha A. DiGruccio   +6 more
wiley   +1 more source

Premature pollen development hinders autonomous self-pollination and promotes insect pollination in soybean (Glycine max L.). [PDF]

Sci Rep
Strelin MM, Aizen MA, Cavigliasso P.
europepmc   +1 more source

Phosphorylation of BigH1 regulates its expression pattern and promotes embryonic development

The FEBS Journal, EarlyView.
Phosphorylation is a key regulator of the linker histone variant BigH1 during Drosophila embryogenesis. We reveal that N‐terminal phosphorylation promotes the timely removal of BigH1 from chromatin. In contrast, C‐terminal phosphorylation supports early nuclear divisions and embryonic viability.
Ramóna Pék, Aladár Pettkó‐Szandtner, Anikó Szabó, Balázs Vedelek, Bence György Gombás, Zoltán Villányi, Péter Vilmos, Imre Miklós Boros, László Henn, Gyula Timinszky   +9 more
wiley   +1 more source

Correction: Correction: Effects of the combination of biochar and organic fertilizer on soil properties and agronomic attributes of soybean (Glycine max L.). [PDF]

PLoS One
Ngui ME, Lin YH, Wei IL, Wang CC, Xu YZ, Lin YH.   +5 more
europepmc   +1 more source

RLIM‐associated neurodevelopmental disorders: From clinical spectrum to molecular mechanisms

The FEBS Journal, EarlyView.
RLIM (RNF12) is an E3 ubiquitin ligase essential for mammalian development. Loss‐of‐function variants cause Tønne–Kalscheuer syndrome, while duplications cause Xq13 duplication syndrome, highlighting RLIM dosage sensitivity. This review summarizes the genetics, clinical features, and molecular mechanisms of RLIM‐associated disorders, integrating ...
Madison Landon, Kyra Swildens, Vera M. Kalscheuer, Cristina Gontan, Francisco Bustos   +4 more
wiley   +1 more source