Results 101 to 110 of about 345,366 (342)
Epigenetic Regulation of DAPK1 and Netrin‐1 Drives Diabetic Encephalopathy
Advanced Science, EarlyView.This study identifies a microRNA (miR)‐216a‐5p/death‐associated protein kinase 1 (DAPK1)/hepatocyte nuclear factor 1 homeobox A (HNF1A)/Netrin‐1 signaling axis in diabetic encephalopathy (DE). In leptin receptor‐deficient (db/db) and streptozotocin (STZ)‐induced diabetic mice, reduced miR‐216a‐5p increases DAPK1 expression, disrupting HNF1A binding to ...
Yang Zhou +13 more
wiley +1 more source
The Vaginal Microenvironment: The Physiologic Role of Lactobacilli
Frontiers in Medicine, 2018 In addition to being a passage for sperm, menstruum, and the baby, the human vagina and its microbiota can influence conception, pregnancy, the mode and timing of delivery, and the risk of acquiring sexually transmitted infections.
Emmanuel Amabebe, Dilly O. C. Anumba
doaj +1 more source
Possible mechanism for changes in glycogen metabolism in unloaded soleus muscle [PDF]
Carbohydrate metabolism has been shown to be affected in a number of ways by different models of hypokinesia. In vivo glycogen levels in the soleus muscle are known to be increased by short-term denervation and harness suspension.
Henriksen, E. J., Tischler, M. E.
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BBA Clinical, 2016 In the human body, glycogen is a branched polymer of glucose stored mainly in the liver and the skeletal muscle that supplies glucose to the blood stream during fasting periods and to the muscle cells during muscle contraction. Glycogen has been identified in other tissues such as brain, heart, kidney, adipose tissue, and erythrocytes, but glycogen ...
Adeva-Andany, María M. +4 more
openaire +3 more sources
Advanced Science, EarlyView.The study reveals that PAXIP1‐associated glutamate‐rich protein 1 (PAGR1), a glucose‐responsive regulator in skeletal muscle, modulates systemic glucose homeostasis and hepatic metabolism. Muscle‐specific PAGR1 deletion enhances insulin signaling, promotes glucose transporter 4 (GLUT4) translocation, and protects against high‐fat‐diet‐induced insulin ...
Chenyun Ding +19 more
wiley +1 more source
Gluconeogenesis and glycogenolysis required in metastatic breast cancer cells
Frontiers in OncologyIntroductionMetabolic adaptability, including glucose metabolism, enables cells to survive multiple stressful environments. Glycogen may serve as a critical storage depot to provide a source of glucose during times of metabolic demand during the ...
Emily Hicks +12 more
doaj +1 more source
Physiological state of reused brewing yeast
Czech Journal of Food Sciences, 2013 In brewing, yeast may be reused many times. A number of yeast repitchings differs significantly among the breweries. Adjusting the number of times a strain may be serially repitched is of great importance for quality and consistency of final products ...
Edyta Kordialik-Bogacka, Anna Diowksz
doaj +1 more source
Effects of pre-exercise carbohydrate consumption on metabolism during exercise [PDF]
, 2016 It is well documented that consuming carbohydrates (CHO) prior to exercise has been shown to alter metabolism. There are many ways that CHO ingestion affects substrate utilization and blood glucose dynamics at the start of exercise.
Montzingo, Luke James
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Advanced Science, EarlyView.Macrophage‐derived Galectin‐3 amplifies TGFβ1 signaling to drive diabetic kidney fibrosis: a novel therapeutic target. Abstract Over 30% of patients with type 2 diabetes develop diabetic kidney disease (DKD), which has emerged as a major contributor to end stage renal disease.
Yibing Chen +17 more
wiley +1 more source
Portacaval shunt for glycogen storage disease and hyperlipidaemia. [PDF]
, 1977 Complete portacaval shunt was used to treat 10 patients with glycogen storage disease. A favourable effect was noted on body growth and a number of metabolic abnormalities.
Benichou, J +3 more
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