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Role of glycogen phosphorylase in liver glycogen metabolism.

Molecular Aspects of Medicine, 2015
Liver glycogen is synthesized after a meal in response to an increase in blood glucose concentration in the portal vein and endocrine and neuroendocrine signals, and is degraded to glucose between meals to maintain blood glucose homeostasis. Glycogen degradation and synthesis during the diurnal cycle are mediated by changes in the activities of ...
L. Agius
semanticscholar   +4 more sources

Affinity of glycogen synthetase to crosslinked glycogen

Biopolymers, 1979
AbstractThe affinity of yeast glycogen synthetase to glycogen modified by crosslinking has been studied under various experimental conditions. It was found that the higher the degree of crosslinking, the lower the affinity of glycogen synthetase to glycogen.
Bauer S, Zemek J, Kuniak L
openaire   +3 more sources

Sodium Butyrate Improves Liver Glycogen Metabolism in Type 2 Diabetes Mellitus.

Journal of Agricultural and Food Chemistry, 2019
Liver plays a central role in modulating blood glucose level. Our most recent findings suggested that supplementation with microbiota metabolite sodium butyrate (NaB) could ameliorate progression of type 2 diabetes mellitus (T2DM) and decrease blood ...
Wenqian Zhang   +11 more
semanticscholar   +1 more source

Glycogen of Mactra

Nature, 1961
GLYCOGENS, branched chain polymers of glucose containing α-1,4-glycoside bonds in the main chains and α-1,6-glycoside bonds at the branch points, have been identified in the tissues of all animals thus far examined1. These polymers are made up of a single kind of sub-unit bonded together by a single type of bond and thus only relatively small ...
Dwain D. Hagerman, Dwain D. Hagerman
openaire   +3 more sources

Nuclear Glycogen and Glycogen Synthase Kinase 3

Biochemical and Biophysical Research Communications, 1998
Glycogen is the principal storage form of glucose in animal cells. It accumulates in electron-dense cytoplasmic granules and is synthesized by glycogen synthase (GS), the rate-limiting enzyme of glycogen deposition. Glycogen synthase kinase-3 (GSK-3) is a protein kinase that phosphorylates GS.
John A. Hanover   +3 more
openaire   +3 more sources

Glycogen and glycogen synthase from pig leucocytes

International Journal of Biochemistry, 1979
Abstract 1. 1. Pig polymorphonuclears and lymphocytes show a lower glycogen content than human leucocytes. 2. 2. The glycogen synthase activity from pig leucocytes has the same value as that from human leucocytes. 3. 3. Two forms of glycogen synthase interconvertible by phosphorylation-dephosphorylation reactions are present in pig ...
F. Pegueroles, R. Cusso
openaire   +3 more sources

Glycogenic hepatopathy

Hepatobiliary & Pancreatic Diseases International, 2018
Glycogenic hepatopathy (GH) is a disorder associated with uncontrolled diabetes mellitus, most commonly type 1, expressed as right upper quadrant abdominal pain, hepatomegaly and increased liver enzymes. The diagnosis may be difficult, because laboratory and imaging tests are not pathognomonic.
Johad, Khoury   +3 more
openaire   +2 more sources

Irisin inhibits hepatic gluconeogenesis and increases glycogen synthesis via the PI3K/Akt pathway in type 2 diabetic mice and hepatocytes.

Clinical science, 2015
Increased glucose production and reduced hepatic glycogen storage contribute to metabolic abnormalities in diabetes. Irisin, a newly identified myokine, induces the browning of white adipose tissue, but its effects on gluconeogenesis and glycogenesis are
Tong-Yan Liu   +10 more
semanticscholar   +1 more source

The interaction of muscle glycogen phosphorylase b with glycogen

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1982
Interaction of muscle glycogen phosphorylase b (EC 2.4.1.1) with glycogen was studied by sedimentation, stopped-flow and temperature-jump methods. The equilibrium enzyme concentration was determined by sedimentation in an analytical ultracentrifuge equipped with absorption optics and a photoelectric scanning system.
N.P. Lissovskaya   +4 more
openaire   +3 more sources

Glycogen Synthase and Glycogen Synthase Kinases

1981
Publisher Summary This chapter focuses on properties and other biochemical and physiological processes related to glycogen synthase and glycogen synthase kinases. The reversible covalent modification of proteins appears to be one of the fundamental mechanisms that have evolved to regulate the inherent properties of enzyme molecules.
openaire   +2 more sources

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