Results 131 to 140 of about 2,890 (187)

Galectin-3: a novel biomarker of glycogen storage disease type III. [PDF]

open access: yesCell Death Discov
Rossiaud L   +11 more
europepmc   +1 more source

Functional proteomics reveals that Slr0237 is a SigE‐regulated glycogen debranching enzyme pivotal for glycogen breakdown

open access: closedPROTEOMICS, 2023
The group 2 σ factor for RNA polymerase SigE plays important role in regulating central carbon metabolism in cyanobacteria. However, the regulation of SigE for these pathways at a proteome level remains unknown. Using a sigE-deficient strain (ΔsigE) of Synechocystis sp.
Yujing Liu, Haitao Ge, Dandan Lu
openalex   +3 more sources

Acceptor Specificity of 4-α-Glucanotransferases of Mammalian Glycogen Debranching Enzymes

open access: closedThe Journal of Biochemistry, 2006
Glycogen debranching enzyme (GDE) has two distinct active sites for its 4-alpha-glucanotransferase and amylo-alpha-1,6-glucosidase activities. The GDE 4-alpha-glucanotransferases of mammals show stringent donor specificity; only alpha-glucans with an alpha-1,6-linked maltotetraosyl or maltotriosyl branch function as donors of a maltotriosyl or maltosyl
Y. Makino, K. Omichi
openalex   +3 more sources

Glycogen Debrancher Enzyme Deficiency Myopathy

Journal of Clinical Neuromuscular Disease, 2021
Abstract Glycogen storage disease type III is a rare inherited disease caused by decreased activity of glycogen debranching enzyme. It affects primarily the liver, cardiac muscle, and skeletal muscle. Pure involvement of the skeletal muscle with adult onset is extremely rare.
Menachem, Sadeh   +2 more
openaire   +2 more sources

Glycogen debranching pathway deduced from substrate specificity of glycogen debranching enzyme

Glycoconjugate Journal, 2022
Glycogen debranching enzyme (GDE) is bifunctional in that it exhibits both 4-α-glucanotransferase and amylo-α-1,6-glucosidase activity at two distinct catalytic sites. GDE converts the phosphorylase-limit biantennary branch [G-G-G-G-(G-G-G-G↔)G-G- residue, where G = D-glucose, hyphens represent α-1,4-glycosidic bonds, and the double-headed arrow ...
Ayato Ikeda   +2 more
openaire   +2 more sources

Crystallization of glycogen debranching enzyme

Journal of Molecular Biology, 1984
Crystals of glycogen debranching enzyme from rabbit skeletal muscle have been obtained from solutions of polyethylene glycol 8000 (pH 7.3) containing 10 mM-linear oligosaccharides of lengths from three to seven glucose units in alpha-1,4 linkage. Preliminary X-ray precession photographs indicate an orthorhombie unit cell with dimensions of a = 106.4 A,
B R, Osterlund   +3 more
openaire   +2 more sources

Glycogen Debranching Enzyme in Bovine Brain

Journal of Biochemistry, 2001
Glycogen debranching enzyme was partially purified from bovine brain using a substrate for measuring the amylo-1,6-glucosidase activity. Bovine cerebrum was homogenized, followed by cell-fractionation of the resulting homogenate. The enzyme activity was found mainly in the cytosolic fraction.
E, Narahara, Y, Makino, K, Omichi
openaire   +2 more sources

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