Multi-omics analysis reveals the carbohydrate-active enzyme repertoire involved in degrading complex arabinoxylans in Penicillium parvum 4-14. [PDF]
Long L +5 more
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Genomic prediction of phytase potential and stress tolerance in maize-associated plant growth-promoting rhizobacterium Enterobacter cloacae Mz49. [PDF]
Amer MA, Hamed SM.
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Splice-modulating antisense oligonucleotides targeting a pathogenic intronic variant in adult polyglucosan body disease correct mis-splicing and restore enzyme activity in patient cells. [PDF]
Thomas R +8 more
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Galectin-3: a novel biomarker of glycogen storage disease type III. [PDF]
Rossiaud L +11 more
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The group 2 σ factor for RNA polymerase SigE plays important role in regulating central carbon metabolism in cyanobacteria. However, the regulation of SigE for these pathways at a proteome level remains unknown. Using a sigE-deficient strain (ΔsigE) of Synechocystis sp.
Yujing Liu, Haitao Ge, Dandan Lu
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Acceptor Specificity of 4-α-Glucanotransferases of Mammalian Glycogen Debranching Enzymes
Glycogen debranching enzyme (GDE) has two distinct active sites for its 4-alpha-glucanotransferase and amylo-alpha-1,6-glucosidase activities. The GDE 4-alpha-glucanotransferases of mammals show stringent donor specificity; only alpha-glucans with an alpha-1,6-linked maltotetraosyl or maltotriosyl branch function as donors of a maltotriosyl or maltosyl
Y. Makino, K. Omichi
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Glycogen Debrancher Enzyme Deficiency Myopathy
Journal of Clinical Neuromuscular Disease, 2021Abstract Glycogen storage disease type III is a rare inherited disease caused by decreased activity of glycogen debranching enzyme. It affects primarily the liver, cardiac muscle, and skeletal muscle. Pure involvement of the skeletal muscle with adult onset is extremely rare.
Menachem, Sadeh +2 more
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Glycogen debranching pathway deduced from substrate specificity of glycogen debranching enzyme
Glycoconjugate Journal, 2022Glycogen debranching enzyme (GDE) is bifunctional in that it exhibits both 4-α-glucanotransferase and amylo-α-1,6-glucosidase activity at two distinct catalytic sites. GDE converts the phosphorylase-limit biantennary branch [G-G-G-G-(G-G-G-G↔)G-G- residue, where G = D-glucose, hyphens represent α-1,4-glycosidic bonds, and the double-headed arrow ...
Ayato Ikeda +2 more
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Crystallization of glycogen debranching enzyme
Journal of Molecular Biology, 1984Crystals of glycogen debranching enzyme from rabbit skeletal muscle have been obtained from solutions of polyethylene glycol 8000 (pH 7.3) containing 10 mM-linear oligosaccharides of lengths from three to seven glucose units in alpha-1,4 linkage. Preliminary X-ray precession photographs indicate an orthorhombie unit cell with dimensions of a = 106.4 A,
B R, Osterlund +3 more
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Glycogen Debranching Enzyme in Bovine Brain
Journal of Biochemistry, 2001Glycogen debranching enzyme was partially purified from bovine brain using a substrate for measuring the amylo-1,6-glucosidase activity. Bovine cerebrum was homogenized, followed by cell-fractionation of the resulting homogenate. The enzyme activity was found mainly in the cytosolic fraction.
E, Narahara, Y, Makino, K, Omichi
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