Results 201 to 210 of about 31,724,613 (234)
ABSTRACT Ceratonia siliqua L. (C. siliqua), commonly known as the carob tree, is an evergreen species of the Fabaceae family native to the Mediterranean basin and increasingly cultivated worldwide. Traditionally valued as animal feed and a natural sweetener, it has recently gained recognition as a multifunctional plant resource with nutritional ...
Anis Ben Hsouna +16 more
wiley +1 more source
Local Suppression of <i>Dgat2</i> Augments Fatty Acid Oxidation in Skeletal Muscle in High-Fat Diet-Fed Mice. [PDF]
Jiyun Y +6 more
europepmc +1 more source
Direct Pharmacological Activation of AMPK Extends Lifespan in Yeast, Worms and Flies
AMP‐activated protein kinase (AMPK) is a key evolutionarily conserved sensor of energy homeostasis, which is implicated in metabolic health and disease, as well as in ageing. Here, we show that direct pharmacological activation of AMPK with the compound 991 in vivo extends lifespan in multiple model organisms: the fission yeast Schizosaccharomyces ...
Eliano dos Santos +15 more
wiley +1 more source
Cardiomyopathy in glycogen storage diseases: diagnosis, prognosis, and advanced management. [PDF]
Patel U +9 more
europepmc +1 more source
Hepatocyte‐specific GHR ablation is associated with hepatic and age‐related pathologies, triggering adipose‐liver crosstalk via elevated circulating GH and subsequent CD36‐dependent hepatic steatosis. This loss impairs STAT5b phosphorylation and enhances PPARγ nuclear activation, upregulating Pdk4 and Cd36 to drive mitochondrial dysfunction and ectopic
Kangkang Yang +7 more
wiley +1 more source
Health-Related Quality of Life in Pediatric Hepatic Glycogen Storage Disease: A Dual-Perspective Study. [PDF]
Aydin O +3 more
europepmc +1 more source
Biallelic Pathogenic Variants in PYGM Impair Retinal Glycogenolysis Causing a Range of Phenotypes. [PDF]
Hussein R +34 more
europepmc +1 more source
AMPKγ2 Regulates Cardiac Hypertrophy and Arrhythmias via Interacting With Myosin. [PDF]
Ge Q +15 more
europepmc +1 more source

