Results 201 to 210 of about 31,724,613 (234)

Ceratonia siliqua: Phytochemistry, Bioactivity, and Its Emerging Role as a Sustainable Food and Industrial Resource

open access: yesJournal of Food Science, Volume 91, Issue 10, October 2026.
ABSTRACT Ceratonia siliqua L. (C. siliqua), commonly known as the carob tree, is an evergreen species of the Fabaceae family native to the Mediterranean basin and increasingly cultivated worldwide. Traditionally valued as animal feed and a natural sweetener, it has recently gained recognition as a multifunctional plant resource with nutritional ...
Anis Ben Hsouna   +16 more
wiley   +1 more source

Direct Pharmacological Activation of AMPK Extends Lifespan in Yeast, Worms and Flies

open access: yesAging Cell, Volume 25, Issue 10, October 2026.
AMP‐activated protein kinase (AMPK) is a key evolutionarily conserved sensor of energy homeostasis, which is implicated in metabolic health and disease, as well as in ageing. Here, we show that direct pharmacological activation of AMPK with the compound 991 in vivo extends lifespan in multiple model organisms: the fission yeast Schizosaccharomyces ...
Eliano dos Santos   +15 more
wiley   +1 more source

Cardiomyopathy in glycogen storage diseases: diagnosis, prognosis, and advanced management. [PDF]

open access: yesHeart Fail Rev
Patel U   +9 more
europepmc   +1 more source

Hepatocyte Growth Hormone Receptor Ablation Is Associated With Aging Phenotypes and Hepatic Mitochondrial Dysfunction

open access: yesAging Cell, Volume 25, Issue 10, October 2026.
Hepatocyte‐specific GHR ablation is associated with hepatic and age‐related pathologies, triggering adipose‐liver crosstalk via elevated circulating GH and subsequent CD36‐dependent hepatic steatosis. This loss impairs STAT5b phosphorylation and enhances PPARγ nuclear activation, upregulating Pdk4 and Cd36 to drive mitochondrial dysfunction and ectopic
Kangkang Yang   +7 more
wiley   +1 more source

Biallelic Pathogenic Variants in PYGM Impair Retinal Glycogenolysis Causing a Range of Phenotypes. [PDF]

open access: yesInvest Ophthalmol Vis Sci
Hussein R   +34 more
europepmc   +1 more source

AMPKγ2 Regulates Cardiac Hypertrophy and Arrhythmias via Interacting With Myosin. [PDF]

open access: yesCirc Res
Ge Q   +15 more
europepmc   +1 more source

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