Results 181 to 190 of about 31,724,613 (234)

Cardiomegaly of Unknown Origin: Why Morphology Still Matters in the Genetic Era - A Case of Cardiac Fabry Disease. [PDF]

Medeni Med J
Makarov I, Roy Y, Mitrofanova L.
europepmc   +1 more source

Integrated Metabolomic and Bioenergetic Profiling Reveals Axl as a Key Regulator of Macrophage Homeostasis

European Journal of Immunology, Volume 56, Issue 10, October 2026.
Axl deficiency disrupts peritoneal macrophage identity and function, impairing glycolysis, TCA metabolism, and mitochondrial respiration while weakening antioxidant defenses. This coordinated metabolic and redox collapse extends systemically, highlighting Axl as a key regulator of immunometabolic homeostasis.
Jesuino R M Ferreira, Thais S Rigoni, Monique S Leandro, Kamila Guimarães‐Pinto, Letícia R Ramos, André L A Costa, Clara F Carvalho, Caroline F Martiniuc, Isadora A Oliveira, Carolina Maia, Júlia Moratelli, Jefferson A Leite, Verônica S Pinto, Adriane Todeschini, Antônio Galina, Alessandra A Filardy   +15 more
wiley   +1 more source

Harnessing Terminalia arjuna in Next Generation Phytomedicine: Cutting Edge Nutraceutical Trends Shaping Food and Health

Food Science &Nutrition, Volume 14, Issue 10, October 2026.
This graphical abstract illustrates the complete translational pipeline of Terminalia arjuna in modern phytomedicine and functional food development. It is rich in key bioactive compounds like arjunolic acid, arjungenin, flavonoids, and tannins which serve as the foundation for the plant's versatile medicinal uses and offers broad therapeutic benefits ...
Ishani Banerjee, Fahika Nazeerulla, Manash Kumar Paul, Sujit Kumar Bhutia, Deblina Basu, Subhadip Mukhopadhyay   +5 more
wiley   +1 more source

Hypoglycemic Effect of Astaxanthin Oil–Fish Oil Complex in Mice With Type 2 Diabetes

Food Science &Nutrition, Volume 14, Issue 10, October 2026.
This study demonstrates that an astaxanthin oil–fish oil complex exerts synergistic hypoglycemic and hepatoprotective effects. It enhances glucose metabolism and relieves oxidative stress in insulin‐resistant HepG2 cells. In high‐fat diet mice, the complex reduces hyperglycemia, improves lipid profiles, and attenuates hepatic steatosis and pancreatic ...
Zhichao Lin, Jianlin He, Xiaomin Xi, Yiping Zhang, Qingqing Le, Yaqi Guo, Hua Fang, Wenhui Jin, Hui Chen, Sijin Chen, Weizhu Chen   +10 more
wiley   +1 more source

Effects of Roasting on the Antioxidant and Lipid‐Modulating Activities of Argania spinosa Oil Under Diabetic Conditions

Food Science &Nutrition, Volume 14, Issue 10, October 2026.
Roasted and non‐roasted Argania spinosa seed oils were evaluated in streptozotocin‐induced diabetic rats. Biochemical and histopathological analyses assessed glucose regulation, lipid metabolism, oxidative stress, liver enzymes, glycogen content, and tissue architecture.
Nour Elhouda Daoudi, Mohammed Aziz, Mohammed Choukri, Youssouf Ali Younous, Amir Bouallegue, Gehan M. Elossaily, Abdel‐Rhman Z. Gaafar, Musa A. Said, Hina Ali, Mohamed Bnouham   +9 more
wiley   +1 more source

Eupatilin Alleviates Acute Myocardial Ischemia‐Reperfusion Injury in Rats via the Akt/GSK‐3β Pathway by Targeting COXs

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 10, October 2026.
It has been reported that eupatilin exerts cardioprotective effects after myocardial ischemia‐reperfusion injury (MIRI). This study further found that Eupatilin alleviated acute MIRI in rats by specifically inhibiting cyclooxygenase enzymes (COXs) and activating the Akt/GSK‐3β pathway, providing a theoretical basis for the application of eupatilin in ...
Min Guo, Qianqian Li, Lili Ji
wiley   +1 more source

Intramuscular Fat as a Biomarker of Muscle Health: Strengths, Limitations and Open Challenges

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 5, October 2026.
ABSTRACT Intramuscular fat (IMF), also known as myosteatosis, refers to the accumulation of lipids within and around skeletal muscle fibres. Excess IMF is increasingly recognised as a sign of poor muscle quality, linked to reductions in strength, power and mobility, and associated with adverse outcomes in metabolic disease, osteoarthritis ...
Christopher Spence, Martin Alberto Belzunce, Anna Di Laura, Johann Henckel, Alister J. Hart   +4 more
wiley   +1 more source

RNA sequencing resolves a novel noncanonical splice-region variant in <i>PHKA2</i> causing glycogen storage disease type IX α2: a case report. [PDF]

Transl Pediatr
Chen F, He J, Cheng H, Shu S.
europepmc   +1 more source

Preparing Genetic Counselors for Advocacy Partnerships: A Novel Internship Model

Journal of Genetic Counseling, Volume 35, Issue 5, October 2026.
ABSTRACT Patient advocacy organizations (PAOs) and genetic counseling have expanded in tandem with the growth of precision medicine. Genetic counseling and PAOs share important goals related to advancing genomic medicine, creating novel possibilities for synergistic collaboration, especially as the sheer number of PAOs focused on genetic conditions ...
Marin Kalista, Lisa Jay Kessler, Deborah Requesens, Kathleen D. Valverde, Rebecca Mueller   +4 more
wiley   +1 more source

Stability of alglucosidase alfa in 0.9% sodium chloride for enzyme replacement therapy in patients with Pompe disease: insights from enzyme activity and cellular uptake measurements. [PDF]

Eur J Hosp Pharm
Barzel I, Brugma JC, Jacobs EH, Hoogeveen-Westerveld M, van der Kuy PHM, Preijers T.   +5 more
europepmc   +1 more source