Results 201 to 210 of about 17,404,319 (246)

Comprehensive Health Predictors of Injury, Illness, and Separation From Service After Enrollment in Special Forces Assessment and Selection: A Two‐Year Longitudinal Study

Stress and Health, Volume 42, Issue 5, October 2026.
ABSTRACT Individuals in physically and cognitively demanding professions face increased risk of injury, illness, and attrition due to repeated exposure to physical and psychological stressors. Identifying modifiable factors associated with these outcomes can guide risk mitigation strategies.
Meaghan E. Beckner, Emily K. Farina, Lauren A. Thompson, Joseph J. Knapik, Stefan M. Pasiakos, James P. McClung, Harris R. Lieberman   +6 more
wiley   +1 more source

Generation of a glycogen storage disease mouse model with fatty liver and its treatment by PPAR-α agonist bezafibrate. [PDF]

Front Pharmacol
Xie Y, Fu G, Fan C, Huang H, Yan J, Jin L.   +5 more
europepmc   +1 more source

Ceratonia siliqua: Phytochemistry, Bioactivity, and Its Emerging Role as a Sustainable Food and Industrial Resource

Journal of Food Science, Volume 91, Issue 10, October 2026.
ABSTRACT Ceratonia siliqua L. (C. siliqua), commonly known as the carob tree, is an evergreen species of the Fabaceae family native to the Mediterranean basin and increasingly cultivated worldwide. Traditionally valued as animal feed and a natural sweetener, it has recently gained recognition as a multifunctional plant resource with nutritional ...
Anis Ben Hsouna, Ravendra Kumar, Manjul Gondwal, Shivangi Chamoli, Bhanu Pratap Singh Gautam, Simranpreet Kaur, Rakesh Kumar Verma, Piyush Kumar, Monika Michalak, Boutheina Ben Akacha, Wirginia Kukula‐Koch, Wojciech Koch, Faical Brini, Wissem Mnif, Rania Ben Saad, Stefania Garzoli, Miroslava Kačániová   +16 more
wiley   +1 more source

Neonatal gene therapy with AAV2/8-LSPhGAA improves hypertrophic cardiomyopathy in the Gaa^c.1826dupA knock-in murine model. [PDF]

Mol Genet Metab
Kan SH, Harb JF, Li S, Kliman A, Andrade-Heckman P, Christensen CL, Han SO, Koeberl DD, Wang RY.   +8 more
europepmc   +1 more source

Direct Pharmacological Activation of AMPK Extends Lifespan in Yeast, Worms and Flies

Aging Cell, Volume 25, Issue 10, October 2026.
AMP‐activated protein kinase (AMPK) is a key evolutionarily conserved sensor of energy homeostasis, which is implicated in metabolic health and disease, as well as in ageing. Here, we show that direct pharmacological activation of AMPK with the compound 991 in vivo extends lifespan in multiple model organisms: the fission yeast Schizosaccharomyces ...
Eliano dos Santos, Marie Blickling, Fiona C. Leiper, John‐Patrick Alao, Claudia Lennicke, Andrea Foley, Jon R. Wilson, Steven J. Gamblin, Bénédicte Chazaud, Giovanna Lollo, Rémi Mounier, Gaëtan Juban, Charalampos Rallis, David Carling, Filipe Cabreiro, Helena M. Cochemé   +15 more
wiley   +1 more source

Early identification of LPIN1 variant in a child with severe myoglobinuria and a history of sibling deaths. [PDF]

CEN Case Rep
Ahmed MMH, Riaz S, Fatima N, Qasim SM.
europepmc   +1 more source

Hepatocyte Growth Hormone Receptor Ablation Is Associated With Aging Phenotypes and Hepatic Mitochondrial Dysfunction

Aging Cell, Volume 25, Issue 10, October 2026.
Hepatocyte‐specific GHR ablation is associated with hepatic and age‐related pathologies, triggering adipose‐liver crosstalk via elevated circulating GH and subsequent CD36‐dependent hepatic steatosis. This loss impairs STAT5b phosphorylation and enhances PPARγ nuclear activation, upregulating Pdk4 and Cd36 to drive mitochondrial dysfunction and ectopic
Kangkang Yang, Yuli Jian, Fusheng Pang, Ming Ying, Qian Yang, Nian Liu, Shujing Wang, Yingjie Wu   +7 more
wiley   +1 more source

A Comprehensive Update on Pompe Disease: From Existing Therapies to Emerging Curative Strategies. [PDF]

Int J Mol Sci
Estevez Barcia R, Colón C, Hermida-Ameijeiras Á, López-Valverde L, Rodrigues D, Domínguez-González C, Díaz-Manera J, Couce ML, Alvarez JV.   +8 more
europepmc   +1 more source

Insights into the modulation of age‐related macular degeneration: Molecular and systems‐level perspectives

Acta Ophthalmologica, Volume 104, Issue S293, Page S4-S35, October 2026.
ENGLISH SUMMARY In developed countries, age‐related macular degeneration (AMD) is the leading cause of visual impairment in the aging population. Understanding of its pathogenesis is limited and the number of patients is predicted to continue rising. AMD is classified into two main forms: dry and neovascular AMD (dAMD and nAMD, respectively).
Hanna Heloterä
wiley   +1 more source