Results 201 to 210 of about 56,617 (329)

Genetic risk variants implicate impaired maintenance and repair of periodontal tissues as causal for periodontitis—A synthesis of recent findings

Periodontology 2000, EarlyView.
AbstractPeriodontitis is a complex inflammatory disease in which the host genome, in conjunction with extrinsic factors, determines susceptibility and progression. Genetic predisposition is the strongest risk factor in the first decades of life. As people age, chronic exposure to the periodontal microbiome puts a strain on the proper maintenance of ...
Arne S. Schaefer, Luigi Nibali, Noha Zoheir, Niki M. Moutsopoulos, Bruno G. Loos   +4 more
wiley   +1 more source

Mapping glycogen accumulation and treatment effect in Pompe disease with saturation transfer MRI. [PDF]

Transl Res
Zeng Q, Li Y, Timm D, Johnson T, Mehta N, Martin L, Fox B, van Zijl PCM, Walter GA, Rosenberg JT, Kooi CWV, Corti M, Gentry MS, Sun RC, Byrne BJ, Yadav NN.   +15 more
europepmc   +1 more source

Prospective exploratory muscle biopsy, imaging, and functional assessment in patients with late-onset Pompe disease treated with alglucosidase alfa: The EMBASSY Study [PDF]

, 2016
et al,, Pestronk, Alan
core   +1 more source

Exercise training to preserve vitality capacity in ageing

Experimental Physiology, EarlyView.
Abstract Ageing is an escalating global health issue, with the World Health Organization (WHO) reporting that one in six individuals will be 60 years or older by the year 2030. Therefore, understanding the mechanisms of complex biological ageing processes and associated healthcare challenges has become increasingly important.
Raymond Jones, Taylor L. Taylor, Robert T. Mankowski, Fitzgerald Dodds, Michael Hankes, Joanna Hobson, Yi Lin, Keith Saffold, Silvienne C. Sint Jago, McKenna A. Tharpe, Emily L. Zumbro, Anna Thalacker‐Mercer, Thomas W. Buford   +12 more
wiley   +1 more source

Genetic Mutations Underlying Growth Impairment and Cardiomyopathies in Children: Molecular Mechanisms, Clinical Implications and Targeted Therapies. [PDF]

Genes (Basel)
Dicorato MM, De Sario G, Carella MC, Guaricci AI, Ciccone MM, Forleo C, D'Amato G, Faienza MF.   +7 more
europepmc   +1 more source

Glycogen storage disease type II (Pompe disease) in children

, 2016
А. N. Semyachkina, В. С. Сухоруков, Т. М. Букина, M. I. Yablonskaya, E. S. Merkuryeva, М. Н. Харабадзе, Е. А. Проскурина, Ekaterina Zakharova, Andrey Brydun, P.A. Shatalov, П. В. Новиков   +10 more
openalex   +1 more source

354. Correction of Respiratory Function by Recombinant AAV1 Mediated Gene Therapy in a Murine Model of Glycogen Storage Disease Type II

, 2005

openalex   +1 more source

Targeted Disruption of the Acid α-Glucosidase Gene in Mice Causes an Illness with Critical Features of Both Infantile and Adult Human Glycogen Storage Disease Type II [PDF]

, 1998
Nina Raben, Kanneboyina Nagaraju, Eunice Lee, Paul Kessler, Barry J. Byrne, Laura Lee, Mary E. LaMarca, Christina D. King, Jerrold M. Ward, Brian Sauer, Paul H. Plötz   +10 more
openalex   +1 more source

The efficacy and physiological bases of small muscle mass exercise in health and disease

Experimental Physiology, EarlyView.
Abstract The conventional approach to aerobic exercise prescription involves large muscle mass exercise and the manipulation of variables such as training intensity, duration and frequency to promote desired adaptations. However, during whole‐body exercise, central limitations (i.e., neural, pulmonary and/or cardiac) constrain exercise tolerance and ...
Callum G. Brownstein
wiley   +1 more source

Metabolic considerations of the portal circulation [PDF]

, 1988
Starzl, TE
core