Results 41 to 50 of about 4,939 (253)

Hemodynamic responses to glycols and to hemolysis

open access: yes, 1969
Ethylene and propylene glycol both decrease renal blood flow in dogs while increasing flow through the superior mesenteric artery. The decrease in renal blood flow is not a passive response to dilatation of major vascular beds since it precedes the ...
Keith MacCannell
core   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Virucidal efficacy of compositions based on lanthanum nitrate hexahydrate

open access: yesЖурнал микробиологии, эпидемиологии и иммунобиологии
Background. The most urgent problem of medicine is the fight against viral diseases. Preventive measures in the form of antiseptics with virucidal effect (VE) play an important role.
Elena V. Berezhnaya   +6 more
doaj   +1 more source

Relationship between Friction Coefficient, Contact Angle and Infrared Absorbance of Polypropylene Glycol on Metal Surface

open access: yesTribology Online, 2013
The kinematic viscosities in the undiluted solutions of propylene glycol and the polypropylene glycols were proportional to their molecular weights, but the friction coefficients and compressibilities in polypropylene glycols hardly depended on their ...
Kazuaki Hachiya, Takao Tanaka
doaj   +1 more source

Polyetylene Glycols as host solvents: applications to organic synthesis

open access: yes, 1979
Polyethylene glycols (PEG) are fair solvents for inorganic salts and organic substrates; their use in some organic reactions is ...
A.Manzocchi   +5 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Synthesis by High-Efficiency Liquid-Phase (HELP) Method of Oligonucleotides Conjugated with High-Molecular Weight Polyethylene Glycols (PEGs)

open access: yesBiological Procedures Online, 1998
The chemical modification of synthetic oligonucleotides has recently been investigated to improve their pharmacological utilization. In addition to chemical alterations of the backbone and of the heterocyclic bases, their conjugation with amphiphylic ...
Bonora GM, Zaramella S, Veronese FM
doaj   +1 more source

Ultrasonic and volumetric behaviour of glycols with sodium ethylparaben in aqueous medium from T = 293.15 to 308.15 K at atmospheric pressure

open access: yesResults in Chemistry, 2020
Volumetric and acoustic analysis is set in motion to inspect the sodium ethylparaben interaction with ethylene glycol, and propylene glycol as a function of temperature. The estimation of apparent molar volume and apparent molar isentropic compression of
Ashima, K.C. Juglan, Harsh Kumar
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

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