Results 51 to 60 of about 4,939 (253)

Sodium Hypochlorite Pentahydrate as a Reagent for the Cleavage of trans-Cyclic Glycols

open access: yes, 2019
Sodium hypochlorite pentahydrate (NaOCl·5H2O) can be used toward the efficient glycol cleavage of trans-cyclic glycols, which are generally resistant to this transformation. Interestingly, the reaction of cis-cyclic glycols with NaOCl·5H2O is slower than
Masayuki Kirihara   +13 more
core   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Contact urticaria with systemic symptoms due to hexylene glycol in a topical corticosteroid: case report and review of hypersensitivity to glycols [PDF]

open access: yes, 2010
We report a case of severe contact urticaria with systemic involvement resembling an anaphylactic reaction, following the application of a topical corticosteroid. This was caused by hexylene glycol, an excipient in the formulation.
Scherer, K.   +5 more
core   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

Activity of Alkanediol Alkanoates against Pathogenic Plant Fungi and

open access: yesNatural Product Communications, 2012
Thirty known dialkanoates of ethylene, propylene and diethylene glycols were synthesized by reacting the glycols with acyl chlorides and their structures confirmed by IR, NMR and mass spectral analyses.
Paraj Shukla   +4 more
doaj   +1 more source

Reactions of bis(chloromethyl) ethers of glycols with sodium alkoxides [PDF]

open access: yes, 1953
1. A study has been made of the chloromethylation of 1,2- and 1,3-propanediols, and this has resulted in the preparation of the two corresponding bis(chloromethyl) ethers, which have not been described previously. 2.
Arbuzov B., Vinokurova G.
core  

ESI-MS/MS for the Differentiation of Diastereomeric Pyrimidine Glycols in Mononucleosides

open access: yes, 2016
Pyrimidine glycols, or 5,6-dihydroxy-5,6-dihydropyrimidines, are primary lesions in DNA induced by reactive oxygen species. In this article, we report the preparation and tandem mass spectrometry (MS/MS) characterization of the two cis diastereomers of ...
Shetty Vivekananda (2943057)   +2 more
core   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

open access: yesFEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav   +4 more
wiley   +1 more source

NUEVA RUTA DE SÍNTESIS DE GLICOLES A PARTIR DE ACEITES VEGETALES INSATURADOS EMPLEANDO CATALIZADORES ÁCIDOS HETEROGÉNEOS NEW SYNTHESIS ROUTE FOR GLYCOLS FROM UNSATURATED VEGETABLE OILS USING HETEROGENEOUS ACIDIC CATALYSTS

open access: yesVitae, 2007
Las estructuras únicas y las características físicas de las grasas proporcionan una amplia gama de aplicaciones; las insaturaciones reactivas de ciertos ácidos grasos se explotan para generar compuestos con mayor diversidad de aplicación (industria ...
Ricardo SUÁREZ M   +2 more
doaj  

Permeation of polyethylene glycols across the tympanic membrane

open access: yesGiant, 2021
Localized and non-invasive delivery of therapeutics across barriers in the body is challenging. Examples include the flux of drugs across the tympanic membrane (TM) for the treatment of middle ear infections, and across the round window to treat inner ...
Wei Zhang   +6 more
doaj   +1 more source

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