Results 131 to 140 of about 422,950 (380)

Differential Compartmentalization of Enzymatic Reactions for Lactate Signaling Across Protocells

Advanced Functional Materials, EarlyView.
Two populations of protocells consisting of giant unilamellar vesicles containing active species and distinct artificial organelles are competent of collective behavior by mimicking production, intercellular communication, and detection of the bioinspired signal molecule lactate. Enzymatic cascade reactions within artificial organelles demonstrate that
Arianna Balestri, Xinan Huang, Emanuel Lörtscher, Cora‐Ann Schoenenberger, Cornelia G. Palivan   +4 more
wiley   +1 more source

Metal Nanoclusters for Cancer Imaging and Treatment

Advanced Functional Materials, EarlyView.
This review aims to provide a comprehensive summary and discussion of the core–shell design capabilities of metal nanoclusters (NCs) at the atomic level for cancer imaging and treatment. It offers essential insights into the design principles of metal NCs while also encouraging the exploration of other nanomaterials and their potential theranostic ...
Haiguang Zhu, Ziping Wang, Qiaofeng Yao, Ping Zhang, Jianping Xie, Xun Yuan   +5 more
wiley   +1 more source

PFKFB2-mediated glycolysis promotes lactate-driven continual efferocytosis by macrophages

Nature Metabolism, 2023
M. Schilperoort, D. Ngai, M. Katerelos, D. Power, I. Tabas   +4 more
semanticscholar   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Effect of macromolecular crowding on the kinetics of glycolytic enzymes and the behaviour of glycolysis in yeast [PDF]

, 2018
Water is involved in all aspects of biological activity, both as a solvent and as a reactant. It is hypothesized that intracellular water is in a highly structured state due to the high concentrations of macromolecules in the cell and that this may ...
Bagatolli, Luis Alberto, Olsen, Lars F., Thoke, Henrik S.   +2 more
core   +3 more sources

Recycling of Thermoplastics with Machine Learning: A Review

Advanced Functional Materials, EarlyView.
This review shows how machine learning is revolutionizing mechanical, chemical, and biological pathways, overcoming traditional challenges and optimizing sorting, efficiency, and quality. It provides a detailed analysis of effective feature engineering strategies and establishes a forward‐looking research agenda for a truly circular thermoplastic ...
Rodrigo Q. Albuquerque, Florian Stephan, Annalena Pongratz, Christian Brütting, Katharina Krause, Holger Ruckdäschel   +5 more
wiley   +1 more source

Enhancing Student Comprehension of Glucose Metabolism Visualization Through Virtual Simulation Platform: An Educational Approach

Pharmacology Research & Perspectives
With the rapid progression of biotechnology, the significance translational research on glycolysis in molecular pharmacology has become increasingly evident.
Luna Ge, Tingting Feng, Shuo Cao, Hang Yin, Yuang Zhang, Jihong Pan, Wei Chen, Kai Cheng, Lin Wang   +8 more
doaj   +1 more source

The adipokine sFRP4 induces insulin resistance and lipogenesis in the liver [PDF]

, 2019
Secreted frizzled-related protein (sFRP) 4 is an adipokine with increased expression in white adipose tissue from obese subjects with type 2 diabetes and non-alcoholic fatty liver disease (NAFLD).
Al-Hasani, Hadi, Barbosa, David, Fahlbusch, Pia, Herzfeld de Wiza, Daniella, Hörbelt, Tina, Knebel, Birgit, Kotzka, Jorg, Lapauw, Bruno, Müller-Wieland, Dirk, Ouwens, Margriet, Thoresen, G Hege, Van de Velde, Frederique, Van Nieuwenhove, Yves   +12 more
core   +1 more source

Microscopically Adaptable Bioink Guide Cell Compartmentalization toward Morphogenesis of a Functional Vasculature‐Like System

Advanced Healthcare Materials, EarlyView.
Contractile vasculatures are fabricated through a one‐step bioprinting strategy. The adaptable microenvironment provided by ECM‐mimicking bioink triggers cell sorting and compartmentalization of endothelial cells and vascular smooth muscle cells toward a histological configuration by focal adhesion kinase‐mediated upregulation of cell adhesion and ...
Jun Chen, Yuqiong Wu, Jiarong Huang, Junjin Jie, Chan Huang, Di Zhang, Yuxin Huang, Rui Mao, Ming Zhao, Lin‐Ping Wu   +9 more
wiley   +1 more source

Isoscopoletin inhibits hepatocellular carcinoma cell proliferation via regulating glycolysis-related proteins.

PLoS ONE
ObjectiveIsoscopoletin is one of the primary metabolites of natural product scoparone, which was reported to against tumor proliferation. The aim of this study was to explore the mechanism of isoscopoletin against hepatocellular carcinoma (HCC ...
Chenyao Ruan, Chen Wang, Jiawen Gu, Zhihui Zhu   +3 more
doaj   +1 more source