Results 281 to 290 of about 422,950 (380)

Increased Tumor Glycolysis Characterizes Immune Resistance to Adoptive T Cell Therapy.

Cell Metabolism, 2018
T. Cascone, Jodi A. McKenzie, Rina M Mbofung, Simone Punt, Zhe Wang, Chunyu Xu, Leila J. Williams, Zhiqiang Wang, C. Bristow, A. Carugo, M. Peoples, Lerong Li, T. Karpinets, Lu Huang, Shruti Malu, C. Creasy, S. Leahey, Jiong Chen, Yuan Chen, H. Pelicano, C. Bernatchez, Y. N. Gopal, T. Heffernan, Jianhua Hu, Jing Wang, R. Amaria, L. Garraway, Peng Huang, Peiying Yang, I. Wistuba, S. Woodman, J. Roszik, R. Davis, M. Davies, J. Heymach, P. Hwu, W. Peng   +36 more
semanticscholar   +1 more source

Redox Cascade in Chicken Skeletal Muscle: SELENOT Suppression in Selenium Deficiency Triggers Disulfidptosis via mtROS‐NADPH Dysregulation

Advanced Science, EarlyView.
Se deficiency downregulates SELENOT, disrupting mitochondrial function and elevating mtROS to induce glucose metabolic reprogramming, NADPH depletion, cysteine accumulation, and disulfidptosis‐mediated actin cytoskeleton collapse in chicken skeletal muscle.
Huanyi Liu, Hao Wu, Ziyu Zhang, Shiwen Xu, Cong Zhou, Tong Xu   +5 more
wiley   +1 more source

The Role of Glycolysis in the Growth of Tumor Cells

, 1961
John Papaconstantinou, Sidney P. Colowick   +1 more
openalex   +1 more source

SIP‐SRS Imaging of Cell Wall Synthesis Identifies a Synergy between Micafungin and Amphotericin B

Advanced Science, EarlyView.
We employed glucose‐d7–based stable isotope probe‐assisted SRS microscopy (SIP‐SRS) C–D imaging to visualize fungal cell wall synthesis and remodeling under antifungal treatment. Amphotericin B (AmB) induced notable daughter cell wall thickening, prompting a combinational therapy with AmB and micafungin.
Meng Zhang, Yuewei Zhan, Haonan Lin, Jiyang Chen, Mohamed N. Seleem, Michael Mansour, Ji‐Xin Cheng   +6 more
wiley   +1 more source

Deacetylation of TALDO1 by HDAC6 promotes glycolysis and nasopharyngeal carcinoma progression through a moonlighting function. [PDF]

Cell Death Dis
Peng X, Zhou P, Zhang K, Chen L, Tang M, Zhou Q, Peng J, Yang L.   +7 more
europepmc   +1 more source

Mitochondrial Glycolysis of Rat Brain and Its Relationship to the Remainder of Cellular Glycolysis

, 1960
Eric G. Brunngraber, Leo G. Abood
openalex   +1 more source

GLYCOLYSIS IN HUMAN BLOOD [PDF]

Journal of Biological Chemistry, 1947
openaire   +2 more sources

Succinic Acid‐Induced Macrophage Endocytosis Promotes Extracellular Vesicle‐Based Integrin Beta1 Transfer Accelerating Fibroblast Activation and Sepsis‐Associated Pulmonary Fibrosis

Advanced Science, EarlyView.
Lipopolysaccharide (LPS) stimulates the production of succinic acid in lung tissue, which promotes macrophages endocytosis and the formation of multivesicular bodies (MVBs). These MVBs release profibrotic extracellular vesicles (EVs), facilitating the transfer of integrin beta1 (ITGβ1) transfer and subsequently activating fibroblasts, thereby ...
Wenyu Yang, Ri Tang, Yang Zhou, Jinquan Zhang, Shuya Mei, Yawen Peng, Xi Huang, Shunpeng Xing, Yuan Gao, Qiaoyi Xu, Zhengyu He   +10 more
wiley   +1 more source

2-Deoxyglucose as a therapeutic strategy for EBV-associated gastric carcinoma: Glycolytic and lytic reactivation inhibition under hypoxic conditions. [PDF]

J Virus Erad
Du Y, Zuo W, Shao Y, Ji Y, Su B, Liang S, Wang D, Li B, Feng Y, Gong L, Chen J, Shao C.   +11 more
europepmc   +1 more source

Novel Evolutionarily Conserved Oncogene COA4 is Driven by KRAS Mutant and Promotes Cancer Metastasis Through Dual Mitochondrial Metabolism‐Dependent and ‐Independent Mechanisms

Advanced Science, EarlyView.
In KRAS‐mutant tumors, KRAS transcriptionally upregulates COA4 via the PI3K/AKT/E2F1 axis, promoting metastasis. Mechanistically, COA4 enhances tumor cell migration through dual pathways: within mitochondria, it boosts oxidative phosphorylation; in the cytoplasm, it binds and activates CDC42 to stimulate pseudopodia formation.
Xingzhao Ji, Weiying Zhang, Fuyuan Xue, Jiazhen Zeng, Qinghua Zhao, Xiaoming Sun, Jian Sun, Heng Zhou, Quanlin Xu, Guoyuan Ma, Shengnan Sun, Ying Wang, Qian Mu, Yi Liu, Qiang Wan   +14 more
wiley   +1 more source