Results 81 to 90 of about 15,705 (221)

Blood group O expression in normal tissues and tumors

The FEBS Journal, Volume 292, Issue 21, Page 5697-5722, November 2025.
The H antigen (O blood group), the precursor to A and B blood groups, is expressed on human erythrocytes. However, reliable reagents for H antigen detection are lacking. We generated two novel monoclonal antibodies using sea lamprey immunization, Tn4‐31L and OmcFL3‐02, that specifically detect the H antigen on glycan microarrays, glycoproteins, and ...
Ea Kristine Clarisse Tulin, Lukas Muerner, Tanya R. McKitrick, Catherine A. Tilton, Lauren E. Pepi, Tianwei Jia, Maxence Noel, Leon Y. Zheng, Sean R. Stowell, Stephan von Gunten, Jamie Heimburg‐Molinaro, Richard D. Cummings   +11 more
wiley   +1 more source

Flowcytometric assessment of fetomaternal hemorrhage during external cephalic version at term [PDF]

, 2008
External cephalic version (ECV) at term is a safe procedure and reduces the incidence of cesarean sections for breech presentation. One of the known complications, however, is an ECV-related disruption of the placental barrier and a subsequent ...
Friese, Klaus, Hermann, Christine, Kachler, Andrea, Kainer, Franz, Scholz, Christoph, Toth, Bettina, Weissenbacher, Tobias   +6 more
core   +2 more sources

Heterogeneity Landscape of Circulating Tumor Cells in Clinical Utility

Advanced Therapeutics, Volume 8, Issue 10, October 2025.
This study reports the heterogeneity spectrum of circulating tumor cells. The factors involved in the spectrum promote CTCs to overcome barriers in the metastatic cascade but impact the clinical outcome of cancer patients. In summary, the heterogeneities in association with CTCs ultimately reduce patient survival and facilitate increasing mortality of ...
Md Kowsar Alam, Lu Yanjun, Bee Luan Khoo, Tongxu Si, Heng Zou, Mengsu Yang   +5 more
wiley   +1 more source

Erythroid anion transport, nitric oxide, and blood pressure

Frontiers in Physiology
Glycophorin A and glycophorin B are structural membrane glycoproteins bound in the band 3 multiprotein complexes on human red blood cells (RBCs). Band 3 is an erythroid-specific anion exchanger (AE1).
Kate Hsu, Kate Hsu, Kate Hsu
doaj   +1 more source

An Alternative to the Human Hemoglobin Test in the Investigation of Bloodstains Treated with Active Oxygen: The Human Glycophorin A Test

The Scientific World Journal, 2011
In criminal investigations, there are three stages involved when studying bloodstains: search and orientation, confirmation, and individualization. Confirmatory tests have two aims: to show that the stain contains a human biological fluid and to confirm ...
Ana Castelló, Francesc Francés, Fernando Verdú   +2 more
doaj   +1 more source

Senp1 drives hypoxia-induced polycythemia via GATA1 and Bcl-xL in subjects with Monge's disease. [PDF]

, 2016
In this study, because excessive polycythemia is a predominant trait in some high-altitude dwellers (chronic mountain sickness [CMS] or Monge's disease) but not others living at the same altitude in the Andes, we took advantage of this human experiment ...
Appenzeller, Otto, Azad, Priti, Bafna, Vineet, Cabrales, Pedro J, Haddad, Gabriel G, Hsiao, Yu Hsin, Poulsen, Orit, Ronen, Roy, Zhao, Huiwen W, Zhou, Dan   +9 more
core  

Atomistic mechanism of transmembrane helix association.

PLoS Computational Biology, 2020
Transmembrane helix association is a fundamental step in the folding of helical membrane proteins. The prototypical example of this association is formation of the glycophorin dimer.
Jan Domański, Mark S P Sansom, Phillip J Stansfeld, Robert B Best   +3 more
doaj   +1 more source

Characterization of blood group variants in an Omani population by comparison of whole genome sequencing and serology

Transfusion, Volume 65, Issue 10, Page 1922-1934, October 2025.
Abstract Background Although blood group variation was first described over a century ago, our understanding of the genetic variation affecting antigenic expression on the red blood cell surface in many populations is lacking. This deficit limits the ability to accurately type patients, especially as serological testing is not available for all ...
Paige E. Haffener, Arwa Z. Al‐Riyami, Shoaib Al‐Zadjali, Mohammed Al‐Rawahi, Saif Al Hosni, Ali Al Marhoobi, Ammar Al Sheriyani, Ellen M. Leffler   +7 more
wiley   +1 more source

Proteomic analysis of ERK1/2-mediated human sickle red blood cell membrane protein phosphorylation

Clinical Proteomics, 2013
Background In sickle cell disease (SCD), the mitogen-activated protein kinase (MAPK) ERK1/2 is constitutively active and can be inducible by agonist-stimulation only in sickle but not in normal human red blood cells (RBCs).
Soderblom Erik J, Thompson J Will, Schwartz Evan A, Chiou Edward, Dubois Laura G, Moseley M Arthur, Zennadi Rahima   +6 more
doaj   +1 more source

Biological functions of blood group antigens [PDF]

, 2009
Os antígenos de grupos sanguíneos eritrocitários são estruturas macromoleculares localizadas na superfície extracelular da membrana eritrocitária. Com o desenvolvimento de estudos moleculares, mais de 250 antígenos são conhecidos e estão organizados em ...
BONIFÁCIO, Silvia L., NOVARETTI, Marcia C. Z.   +1 more
core   +1 more source