Heterogeneity Landscape of Circulating Tumor Cells in Clinical Utility
Advanced Therapeutics, Volume 8, Issue 10, October 2025.This study reports the heterogeneity spectrum of circulating tumor cells. The factors involved in the spectrum promote CTCs to overcome barriers in the metastatic cascade but impact the clinical outcome of cancer patients. In summary, the heterogeneities in association with CTCs ultimately reduce patient survival and facilitate increasing mortality of ...
Md Kowsar Alam +5 more
wiley +1 more source
The Scientific World Journal, 2011 In criminal investigations, there are three stages involved when studying bloodstains: search and orientation, confirmation, and individualization. Confirmatory tests have two aims: to show that the stain contains a human biological fluid and to confirm ...
Ana Castelló +2 more
doaj +1 more source
Population genetics of GYPB and association study between GYPB*S/s polymorphism and susceptibility to P. falciparum infection in the Brazilian Amazon. [PDF]
PLoS ONE, 2011 Merozoites of Plasmodium falciparum invade through several pathways using different RBC receptors. Field isolates appear to use a greater variability of these receptors than laboratory isolates.
Eduardo Tarazona-Santos +12 more
doaj +1 more source
Senp1 drives hypoxia-induced polycythemia via GATA1 and Bcl-xL in subjects with Monge's disease. [PDF]
, 2016 In this study, because excessive polycythemia is a predominant trait in some high-altitude dwellers (chronic mountain sickness [CMS] or Monge's disease) but not others living at the same altitude in the Andes, we took advantage of this human experiment ...
Appenzeller, Otto +9 more
core
A Polynesian family showing co-dominant inheritance of normal glycophorin C and the Gerbich variant form of glycophorin C [PDF]
Immunohematology, 1992 Abstract Two individuals with the rare Ge:−2,−3,4 phenotype (Gerbich type of Gerbich negative) were identified in a family of Polynesian descent who reside in the Cook Islands. In initial serologic tests, all other family members typed as Ge-positive, and heterozygous individuals could not be identified.
M E, Reid +3 more
openaire +2 more sources
Dynamics of the Glycophorin A Dimer in Membranes of Native-Like Composition Uncovered by Coarse-Grained Molecular Dynamics Simulations. [PDF]
PLoS ONE, 2015 Membranes are central for cells as borders to the environment or intracellular organelle definition. They are composed of and harbor different molecules like various lipid species and sterols, and they are generally crowded with proteins.
Nadine Flinner, Enrico Schleiff
doaj +1 more source
Transfusion, Volume 65, Issue 10, Page 1922-1934, October 2025.Abstract Background Although blood group variation was first described over a century ago, our understanding of the genetic variation affecting antigenic expression on the red blood cell surface in many populations is lacking. This deficit limits the ability to accurately type patients, especially as serological testing is not available for all ...
Paige E. Haffener +7 more
wiley +1 more source
Biological functions of blood group antigens [PDF]
, 2009 Os antígenos de grupos sanguíneos eritrocitários são estruturas macromoleculares localizadas na superfície extracelular da membrana eritrocitária. Com o desenvolvimento de estudos moleculares, mais de 250 antígenos são conhecidos e estão organizados em ...
BONIFÁCIO, Silvia L. +1 more
core +1 more source
Beyond FimH: Diversity and Relevance of Carbohydrate‐Binding Fimbrial Proteins in Escherichia coli
ChemBioChem, Volume 26, Issue 17, September 15, 2025.This review discusses fimbrial lectins found in Escherichia coli (E. coli) other than FimH, which could be targeted to treat E. coli pathogenicity as an alternative to antibiotic treatment. Escherichia coli (E. coli) is responsible for multiple diseases in humans and animals.
Oliwier R. Dulawa +3 more
wiley +1 more source
Quantitative phospho-proteomics reveals the Plasmodium merozoite triggers pre-invasion host kinase modification of the red cell cytoskeleton [PDF]
, 2015 The invasive blood-stage malaria parasite - the merozoite - induces rapid morphological changes to the target erythrocyte during entry. However, evidence for active molecular changes in the host cell that accompany merozoite invasion is lacking. Here, we
Angrisano, Fiona +6 more
core +5 more sources