Results 1 to 10 of about 2,700 (196)

Immunosuppressive glycoproteins associate with breast tumor fibrosis and aggression [PDF]

open access: yesMatrix Biology Plus, 2022
Tumors feature elevated sialoglycoprotein content. Sialoglycoproteins promote tumor progression and are linked to immune suppression via the sialic acid-Siglec axis.
Kevin James Metcalf   +6 more
doaj   +5 more sources

Diversity of sialic acids and sialoglycoproteins in gametes and at fertilization [PDF]

open access: yesFrontiers in Cell and Developmental Biology, 2022
Sialic acids are a family of 9-carbon monosaccharides with particular physicochemical properties. They modulate the biological functions of the molecules that carry them and are involved in several steps of the reproductive process.
Ingrid Fliniaux   +8 more
doaj   +6 more sources

Diagnostic informativeness of markers of bone-tissue metabolism and bone resorption in cows with osteodystrophy [PDF]

open access: yesRegulatory Mechanisms in Biosystems, 2023
Osteodystrophy is caused by polyetiological factors, the main being disturbance of metabolism of macroelements and D and A vitamins. The disease continues to impose great economic losses on animal husbandry, reduces cattle productivity, and hinders ...
L. G. Slivinska   +8 more
doaj   +3 more sources

Identification of novel tumor-associated cell surface sialoglycoproteins in human glioblastoma tumors using quantitative proteomics. [PDF]

open access: yesPLoS ONE, 2014
Glioblastoma multiform (GBM) remains clinical indication with significant "unmet medical need". Innovative new therapy to eliminate residual tumor cells and prevent tumor recurrences is critically needed for this deadly disease.
François Autelitano   +15 more
doaj   +3 more sources

Gangliosides in milk [PDF]

open access: yesMljekarstvo, 2016
Gangliosides belong to a group of glycosphingolipids which are naturally found in biological tissues and fluids including mammalian milks. Considering milk, gangliosides are exclusively found in the membrane of the milk fat globule.
Slavica Potočki, Marko Mesarić
doaj   +3 more sources

Siglec Ligands

open access: yesCells, 2021
A dense and diverse array of glycans on glycoproteins and glycolipids decorate all cell surfaces. In vertebrates, many of these carry sialic acid, in a variety of linkages and glycan contexts, as their outermost sugar moiety.
Anabel Gonzalez-Gil, Ronald L. Schnaar
doaj   +1 more source

NEU1 and NEU3 enzymes alter CD22 organization on B cells

open access: yesBiophysical Reports, 2022
The B cell membrane expresses sialic-acid-binding immunoglobulin-like lectins, also called Siglecs, that are important for modulating immune response. Siglecs have interactions with sialoglycoproteins found on the same membrane (cis-ligands) that result ...
Hanh-Thuc Ton Tran   +3 more
doaj   +1 more source

Glycosylation of erythrocyte spectrin and its modification in visceral leishmaniasis. [PDF]

open access: yesPLoS ONE, 2011
Using a lectin, Achatinin-H, having preferential specificity for glycoproteins with terminal 9-O-acetyl sialic acid derivatives linked in α2-6 linkages to subterminal N-acetylgalactosamine, eight distinct disease-associated 9-O-acetylated ...
Sajal Samanta   +10 more
doaj   +1 more source

Sugar Coating: Utilisation of Host Serum Sialoglycoproteins by Schistosoma mansoni as a Potential Immune Evasion Mechanism

open access: yesPathogens, 2022
Parasitic helminths resort to various mechanisms to evade and modulate their host’s immune response, several of which have been described for Schistosoma mansoni.
Maude Dagenais   +3 more
doaj   +1 more source

Scrapie PrP 27-30 is a sialoglycoprotein [PDF]

open access: yesJournal of Virology, 1985
The major scrapie prion protein, designated PrP 27-30, exhibited both charge and size heterogeneity after purification from infected hamster brains. Eight or more discrete charge isomers of PrP 27-30 with isoelectric points ranging from approximately pH 4.6 to 7.9 were found by using non-equilibrium pH gradient electrophoresis in the first dimension ...
D C, Bolton, R K, Meyer, S B, Prusiner
openaire   +2 more sources

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