Targeted Identification of Metastasis-Associated Cell-Surface Sialoglycoproteins in Prostate Cancer [PDF]
Covalent attachment of carbohydrates to proteins is one of the most common post-translational modifications. At the cell surface, sugar moieties of glycoproteins contribute to molecular recognition events involved in cancer metastasis.
Yang, Lifang +9 more
core +2 more sources
Sialoglycosylation of RBC in visceral leishmaniasis leads to enhanced oxidative stress, calpain-induced fragmentation of spectrin and hemolysis. [PDF]
Visceral leishmaniasis (VL) caused by the intracellular parasite Leishmania donovani accounts for an estimated 12 million cases of human infection. It is almost always associated with anemia, which severely complicates the disease course.
Sajal Samanta +5 more
doaj +1 more source
Appearance of sialoglycoproteins in encysting cells of Entamoeba histolytica [PDF]
Amoeba-bacterium cultures of Entamoeba histolytica transferred to a hypoosmotic medium depleted of nutrients changed morphologically and biochemically. The cells ejected grains of rice starch, rounded up, and formed a distinct cell wall that was resistant to detergent, bound the sialic acid-specific lectin from Limulus polyphemus, and became ...
A, Chayen +3 more
openaire +2 more sources
Classification of identified sialoglycoproteins by GO annotation. [PDF]
(A) Cellular components were assigned using Ingenuity Pathway Analysis Knowledge Base (http://ingenuity.com/), the Human Protein Reference Database (http://www.hprd.org/), and the Gene Ontology (GO) Consortium (http://geneontology.org/).
Steven A. Goldman (652727) +15 more
core +1 more source
Sialoglycoproteins adsorbed by Pseudomonas aeruginosa facilitate their survival by impeding neutrophil extracellular trap through siglec-9 [PDF]
PA is an opportunistic pathogen that is commonly associated with severe infection in immunocompromised hosts. Siglec-9 binds with Sias by cis interaction on the neutrophil surface, thereby reducing immunological activity.
Biswajit Khatua +5 more
core +1 more source
The 4.1.(-) hereditary elliptocytosis.
The 4.1(-) hereditary elliptocytosis is a variety of hereditary elliptocytosis that results from the partial or total absence of skeletal protein 4.1.
J. Delaunay, N. Alloisio, L. Morle
doaj +1 more source
Hypoxia-downregulated Siglec-9 glycan ligands induce abnormal activation of platelet
Objective To investigate the expression of sialic acid-binding immunoglobulin-like lectin-9 (Siglec-9)/E ligands in hypoxic condition and its effect on platelet activation.
SHE Yuanting +4 more
doaj +1 more source
Sialoglycoproteins and penultimate sugar expression pattern in developing murine olfactory and respiratory mucosa [PDF]
Sialic acid residues are constant constituents of the glycoproteins of the airways in all species. Sialoglycoproteins are the main acidic glycoprotein and their functions are to mediate cell adherence, to control the viscoelasticity of mucus and to serve
윤주헌, 김경수
core +1 more source
Sialic acid: a sweet swing between mammalian host and Trypanosoma cruzi
Commonly found at the outermost ends of complex carbohydrates in extracellular medium or on outer cell membranes, sialic acids play important roles in a myriad of biological processes.
Leonardo eFreire-de-Lima +6 more
doaj +1 more source
Kinetic analysis of the influenza A virus HA/NA balance reveals contribution of NA to virus-receptor binding and NA-dependent rolling on receptor-containing surfaces. [PDF]
Interactions of influenza A virus (IAV) with sialic acid (SIA) receptors determine viral fitness and host tropism. Binding to mucus decoy receptors and receptors on epithelial host cells is determined by a receptor-binding hemagglutinin (HA), a receptor ...
Hongbo Guo +11 more
doaj +1 more source

