Results 41 to 50 of about 2,977 (189)
Advanced Healthcare Materials, Volume 15, Issue 13, 3 April 2026.This manuscript describes the cultivation of viable microvessels from cryopreserved human brain tissue. When embedded in hydrogels and cultured in microfluidic devices, these microvessels exhibit complex architectures reminiscent of arterioles and capillaries, can be perfused, and display intact barrier function. Collectively, these results demonstrate
Brian J. O'Grady +5 more
wiley +1 more source
How Does Biological Sex Impact Mucosal Bacterial Infection? Mucosal Defenses and Bacterial Detection
Immunological Reviews, Volume 338, Issue 1, March 2026.ABSTRACT Urinary tract infections possess substantial sex disparities in the incidence, immune response, and progression of infection. Some of these distinctions may be due to sexual dimorphism in mucosal barriers or sex differences in the initial immune response to infection.
Laura Ramirez Finn, Molly A. Ingersoll
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Sialoglycoproteins of ejaculated human spermatozoa and seminal plasma [PDF]
International Journal of Andrology, 1984 Ejaculated human sperm were found to possess three major sialoglycoproteins with molecular weights of 30 000, 14 000 and 12 000 and one minor species of 18 000. Liquefied seminal plasma from normal donors contain two major sialoglycoproteins with molecular weights of 17 000 and 15 000 and two minor species of 70 000 and 54 000.
C, Wongkome, M, Chulavatnatol
openaire +2 more sources
PLoS ONE, 2013 Aberrant glycosylation is a common feature of many malignancies including colorectal cancers (CRCs). About 15% of CRC show the microsatellite instability (MSI) phenotype that is associated with a high frequency of biallelic frameshift mutations in the ...
Jennifer Lee +6 more
doaj +1 more source
Generating golden Syrian hamsters with conditional alleles via zygote microinjection of CRISPR/Cas9
Animal Models and Experimental Medicine, Volume 9, Issue 2, Page 308-318, February 2026.We established the first conditional knockout (cKO) model in the golden Syrian hamster by CRISPR/Cas9‐mediated genome editing. Cas9 protein, two sgRNAs, and a donor plasmid carrying loxP‐flanked exon 2 of the ApoF gene were microinjected into one‐cell embryos. The floxed allele was efficiently generated (up to 27%) and transmitted through the germline.
Wei Chen +16 more
wiley +1 more source
Case Reports in Pathology, Volume 2026, Issue 1, 2026.Background Intestinal lymphangiectasia is a rare disorder characterized by dilated lymphatic vessels in the gastrointestinal tract, typically presenting with protein‐losing enteropathy. Adult‐onset cases with severe gastrointestinal bleeding are exceptionally rare.
Nasibeh Sargazi Moghadaam +5 more
wiley +1 more source
Dermatologic Therapy, Volume 2026, Issue 1, 2026.The distinction between vascular anomalies is clinically challenging due to their similar clinical presentations and pathological features. This study assessed the immunohistochemical expression of ERG, CD31, CD34, and D2‐40 in representative vascular tumors and lymphatic malformation‐associated lesions to evaluate their diagnostic value and inform ...
Lurun Wang +5 more
wiley +1 more source
Transcriptome analysis of granulation tissue from periodontal osseous defects
Journal of Periodontology, Volume 96, Issue 12, Page 1379-1390, December 2025.Abstract Background Granulation tissue is routinely discarded in periodontal surgical procedures, but few studies have characterized it. The present study aimed to compare global gene expression in granulation tissue derived from different types of periodontal osseous defects.
Ye Han Sam +5 more
wiley +1 more source
Journal of Neuroinflammation, 2018 Background The extension of sepsis encompassing the preterm newborn’s brain is often overlooked due to technical challenges in this highly vulnerable population, yet it leads to substantial long-term neurodevelopmental disabilities.
Ekaterina P. Demina +9 more
doaj +1 more source
Counting glomeruli in human kidney specimens using ex vivo MRI without contrast agents
Magnetic Resonance in Medicine, Volume 94, Issue 6, Page 2519-2528, December 2025.Abstract Purpose The total number of glomeruli is an important indicator of kidney function and susceptibility to disease. Glomeruli, however, are difficult to image using MRI without contrast enhancement. For this reason, previous studies have used cationic ferritin as a contrast agent to detect glomeruli in ex vivo and in vivo perfused kidneys.
Nyoman D. Kurniawan +11 more
wiley +1 more source