Results 41 to 50 of about 3,818 (205)
Synthesis of N-Glycolylneuraminic Acid (Neu5Gc) and Its Glycosides. [PDF]
, 2019 Sialic acids constitute a family of negatively charged structurally diverse monosaccharides that are commonly presented on the termini of glycans in higher animals and some microorganisms.
Chen, Xi +2 more
core +2 more sources
Human small cell lung cancer cell line (NCI-H146) tumor behaviour on the chicken embryo chorioallantoic membrane after the sodium valproate treatment [PDF]
, 2017 Small cell lung cancer (SCLC) is an aggressive form of cancer with 5-year survival rate and poor prognosis. Since patients' initial response to therapy is rapidly followed by a relapse with the drug-resistant disease, new therapies are required.
Balnytė, Ingrida +4 more
core +2 more sources
Sialoglycoproteins of ejaculated human spermatozoa and seminal plasma [PDF]
International Journal of Andrology, 1984 Ejaculated human sperm were found to possess three major sialoglycoproteins with molecular weights of 30 000, 14 000 and 12 000 and one minor species of 18 000. Liquefied seminal plasma from normal donors contain two major sialoglycoproteins with molecular weights of 17 000 and 15 000 and two minor species of 70 000 and 54 000.
C, Wongkome, M, Chulavatnatol
openaire +2 more sources
Journal of Cellular and Molecular Medicine, Volume 30, Issue 9, May 2026.ABSTRACT Preeclampsia is a severe gestational complication whose molecular pathogenesis remains poorly understood despite extensive research. It is now recognized that both maternal and fetal cells contribute to disease progression. Notably, single‐cell RNA sequencing of cord blood cells from preeclamptic pregnancies has not been previously ...
Polina Vishnyakova +14 more
wiley +1 more source
Vectorial targeting of an endogenous apical membrane sialoglycoprotein and uvomorulin in MDCK cells. [PDF]
, 1990 We studied the cell-surface delivery pathways of newly synthesized membrane glycoproteins in MDCK cells and for this purpose we characterized an endogenous apical integral membrane glycoprotein.
Le Bivic, A +3 more
core
Advanced Healthcare Materials, Volume 15, Issue 13, 3 April 2026.This manuscript describes the cultivation of viable microvessels from cryopreserved human brain tissue. When embedded in hydrogels and cultured in microfluidic devices, these microvessels exhibit complex architectures reminiscent of arterioles and capillaries, can be perfused, and display intact barrier function. Collectively, these results demonstrate
Brian J. O'Grady +5 more
wiley +1 more source
How Does Biological Sex Impact Mucosal Bacterial Infection? Mucosal Defenses and Bacterial Detection
Immunological Reviews, Volume 338, Issue 1, March 2026.ABSTRACT Urinary tract infections possess substantial sex disparities in the incidence, immune response, and progression of infection. Some of these distinctions may be due to sexual dimorphism in mucosal barriers or sex differences in the initial immune response to infection.
Laura Ramirez Finn, Molly A. Ingersoll
wiley +1 more source
PLoS ONE, 2013 Aberrant glycosylation is a common feature of many malignancies including colorectal cancers (CRCs). About 15% of CRC show the microsatellite instability (MSI) phenotype that is associated with a high frequency of biallelic frameshift mutations in the ...
Jennifer Lee +6 more
doaj +1 more source
Generating golden Syrian hamsters with conditional alleles via zygote microinjection of CRISPR/Cas9
Animal Models and Experimental Medicine, Volume 9, Issue 2, Page 308-318, February 2026.We established the first conditional knockout (cKO) model in the golden Syrian hamster by CRISPR/Cas9‐mediated genome editing. Cas9 protein, two sgRNAs, and a donor plasmid carrying loxP‐flanked exon 2 of the ApoF gene were microinjected into one‐cell embryos. The floxed allele was efficiently generated (up to 27%) and transmitted through the germline.
Wei Chen +16 more
wiley +1 more source
Does NETosis Contribute to the Bacterial Pathoadaptation in Cystic Fibrosis? [PDF]
, 2014 Significant advances in our understanding of neutrophil biology were made in the past several years. The exciting discovery that neutrophils deploy neutrophil extracellular traps (NETs) to catch pathogens paved the way for a series of additional studies ...
Gadjeva, Mihaela, Rahman, Samir
core +1 more source