Results 61 to 70 of about 2,977 (189)

Know Your ABCs: Discovery, Differentiation, and Targeting of T‐Bet+ B Cells

Immunological Reviews, Volume 330, Issue 1, March 2025.
ABSTRACT Since their first description in 2008, T‐bet+ B cells have emerged as a clinically important B cell subset. Now commonly known as ABCs (Age‐associated B Cells), they are uniquely characterized by their expression of the transcription factor T‐bet. Indeed, this singular factor defines this B cell subset.
Gary M. Winslow, Russell Levack
wiley   +1 more source

Classification of identified sialoglycoproteins by GO annotation.

, 2014
(A) Cellular components were assigned using Ingenuity Pathway Analysis Knowledge Base (http://ingenuity.com/), the Human Protein Reference Database (http://www.hprd.org/), and the Gene Ontology (GO) Consortium (http://geneontology.org/).
Steven A. Goldman (652727), Michael Smith (26855), Pascual Ferrara (479981), Denis Loyaux (479980), Philippe Fabre (652723), Sébastien Roudières (652720), Romane Auvergne (652725), Jean-Claude Guillemot (479982), Catherine Déon (652721), Vasudeo Badarinarayana (652726), Su Wang (191010), Paul August (652728), Sridaran Natesan (245186), Frédérique Guette (652722), François Autelitano (652719), Qinggong Ping (652724)   +15 more
core   +1 more source

α-N-Acetylglucosamine-Linked O-Glycans of Sialoglycoproteins (Tc-Mucins) From Trypanosoma Cruzi Colombiana Strain [PDF]

, 2009
Trypanosoma cruzi sialoglycoproteins (Tc-mucins) are mucin-like molecules linked to a parasite membrane via a glycosylphosphatidylinositol anchor. We previously determined the structures of Tc-mucin O-glycan domains from several T.
Previato, José O., de Almeida, Eliane G., Todeschini, Adriane R., Mendonça-Previato, Lucia, Agrellos, Orlando A., Jones, Christopher   +5 more
core   +1 more source

Unveiling VCAM‐1’s Multifaceted Role in Secondary Diabetic Complications

Journal of Food Quality, Volume 2025, Issue 1, 2025.
Diabetes mellitus is a chronic metabolic disorder characterized by sustained hyperglycemia, tightly interlinked with a range of severe secondary complications. Diabetic retinopathy, nephropathy, and cardiomyopathy substantially contribute to the overall morbidity and mortality associated with diabetes.
Prabhnain Kaur, Ritu, Kalicharan Sharma, Ramesh K. Goyal, Parakh Basist, Rahmuddin Khan, Abdulsalam Alhalmi, Mohamed Addi   +7 more
wiley   +1 more source

Sialoglycoproteins adsorbed by Pseudomonas aeruginosa facilitate their survival by impeding neutrophil extracellular trap through siglec-9

, 2012
PA is an opportunistic pathogen that is commonly associated with severe infection in immunocompromised hosts. Siglec-9 binds with Sias by cis interaction on the neutrophil surface, thereby reducing immunological activity.
Biswajit Khatua, Bhattacharya, Kaushik, Chitra Mandal, Mandal, Chitra, Kaushik Bhattacharya, Khatua, Biswajit   +5 more
core   +1 more source

Flow-cytometric monitoring of disease-associated expression of 9-O-acetylated sialoglycoproteins in combination with known CD antigens, as an index for MRD in children with acute lymphoblastic leukaemia: a two-year longitudinal follow-up study

BMC Cancer, 2008
Background Over expression of 9-O-acetylated sialoglycoproteins (Neu5,9Ac2-GPs, abbreviated as OAcSGP) has been demonstrated as a disease-associated antigen on the lymphoblasts of childhood acute lymphoblastic leukaemia (ALL).
Chandra Sarmila, Mandal Chandan, Bandyopadhyay Suman, Chowdhury Suchandra, Mandal Chitra   +4 more
doaj   +1 more source

Overcoming the Blood–Brain Barrier: Multifunctional Nanomaterial‐Based Strategies for Targeted Drug Delivery in Neurological Disorders

Small Science, Volume 4, Issue 12, December 2024.
This review explores the diverse range of nanomaterials, including polymer, lipid, gold, magnetic, and carbon‐based nanostructures, capable of effectively passing the blood–brain barrier (BBB). Moreover, the structure and function of the BBB in both healthy and diseased states are discussed and the potential of nanotechnology in bypassing the BBB to ...
Callan D. McLoughlin, Sarah Nevins, Joshua B. Stein, Mehrdad Khakbiz, Ki‐Bum Lee   +4 more
wiley   +1 more source

Sialoglycoproteins and penultimate sugar expression pattern in developing murine olfactory and respiratory mucosa

, 1998
Sialic acid residues are constant constituents of the glycoproteins of the airways in all species. Sialoglycoproteins are the main acidic glycoprotein and their functions are to mediate cell adherence, to control the viscoelasticity of mucus and to serve
윤주헌, 김경수
core   +1 more source

Affinity purification of biotinylated cell surface sialoglycoproteins.

, 2014
U373 MG cells, primary GBM cells (SIDs), adult (AL) and fetal (ASG6 and ASG7) astrocytes, and neural progenitor cells (NPC) were metabolically labelled with 25 µM Ac4ManNAz for 2 days and conjugated with 50 µM biotin-phosphine capture reagent.
Steven A. Goldman (652727), Michael Smith (26855), Pascual Ferrara (479981), Denis Loyaux (479980), Philippe Fabre (652723), Sébastien Roudières (652720), Romane Auvergne (652725), Jean-Claude Guillemot (479982), Catherine Déon (652721), Vasudeo Badarinarayana (652726), Su Wang (191010), Paul August (652728), Sridaran Natesan (245186), Frédérique Guette (652722), François Autelitano (652719), Qinggong Ping (652724)   +15 more
core   +1 more source

Siglec‐7 and Siglec‐9 expression in primary triple negative and oestrogen receptor positive breast cancer and in vitro signalling

Clinical &Translational Immunology, Volume 13, Issue 9, September 2024.
In this study, we found high Siglec‐7 and Siglec‐9 (ligand) expression in triple negative breast cancer, and to a lower extent in oestrogen receptor positive breast cancer. Moreover, signalling experiments demonstrated that Siglec‐7 signalling is induced by triple negative breast cancer cell lines.
Eline JH van Houtum, Anne HC Valk, Daniel Granado, Jasper Lok, Lune van den Bogaard, Naomi Remkes, Jesper van Eck van der Sluijs, Paul N Span, Lenneke AM Cornelissen, Gosse J Adema   +9 more
wiley   +1 more source