Results 71 to 80 of about 3,818 (205)

Overcoming the Blood–Brain Barrier: Multifunctional Nanomaterial‐Based Strategies for Targeted Drug Delivery in Neurological Disorders

Small Science, Volume 4, Issue 12, December 2024.
This review explores the diverse range of nanomaterials, including polymer, lipid, gold, magnetic, and carbon‐based nanostructures, capable of effectively passing the blood–brain barrier (BBB). Moreover, the structure and function of the BBB in both healthy and diseased states are discussed and the potential of nanotechnology in bypassing the BBB to ...
Callan D. McLoughlin, Sarah Nevins, Joshua B. Stein, Mehrdad Khakbiz, Ki‐Bum Lee   +4 more
wiley   +1 more source

Silkworm expression system as a platform technology in life science [PDF]

, 2009
Many recombinant proteins have been successfully produced in silkworm larvae or pupae and used for academic and industrial purposes. Several recombinant proteins produced by silkworms have already been commercialized.
00397366, 2907, 2907, 2910, 2910, 4521, 4522, 4d68973e-f6ff-4d7d-9439-c121d8831040, 90238246, bd6a76a9-51e0-42ce-9e57-130004af2bc5, Kajikawa, Mizuho, Kato, Tatsuya, Maenaka, Katsumi, Park, Enoch Y.   +13 more
core   +2 more sources

Flow-cytometric monitoring of disease-associated expression of 9-O-acetylated sialoglycoproteins in combination with known CD antigens, as an index for MRD in children with acute lymphoblastic leukaemia: a two-year longitudinal follow-up study

BMC Cancer, 2008
Background Over expression of 9-O-acetylated sialoglycoproteins (Neu5,9Ac2-GPs, abbreviated as OAcSGP) has been demonstrated as a disease-associated antigen on the lymphoblasts of childhood acute lymphoblastic leukaemia (ALL).
Chandra Sarmila, Mandal Chandan, Bandyopadhyay Suman, Chowdhury Suchandra, Mandal Chitra   +4 more
doaj   +1 more source

A case of extravascular hemolysis with Tk‐activation [PDF]

, 2014
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/108281/1/ccr380 ...
Davenport, Robertson D., Yamada, Chisa
core   +1 more source

Siglec‐7 and Siglec‐9 expression in primary triple negative and oestrogen receptor positive breast cancer and in vitro signalling

Clinical &Translational Immunology, Volume 13, Issue 9, September 2024.
In this study, we found high Siglec‐7 and Siglec‐9 (ligand) expression in triple negative breast cancer, and to a lower extent in oestrogen receptor positive breast cancer. Moreover, signalling experiments demonstrated that Siglec‐7 signalling is induced by triple negative breast cancer cell lines.
Eline JH van Houtum, Anne HC Valk, Daniel Granado, Jasper Lok, Lune van den Bogaard, Naomi Remkes, Jesper van Eck van der Sluijs, Paul N Span, Lenneke AM Cornelissen, Gosse J Adema   +9 more
wiley   +1 more source

Identification and partial purification of K88ab Escherichia coli receptor proteins in porcine brush border membranes [PDF]

, 2010
Six receptor proteins, with molecular masses ranging from 94 to 27 kDa, that bind to Escherichia coli K88ab fimbriae were recovered from brush border membranes and were detected after solubilization with Triton X-114.
J. Soler, M. Caloca, S. Suárez
core   +1 more source

CNS/PNS proteoglycans functionalize neuronal and astrocyte niche microenvironments optimizing cellular activity by preserving membrane polarization dynamics, ionic microenvironments, ion fluxes, neuronal activation, and network neurotransductive capacity

Journal of Neuroscience Research, Volume 102, Issue 7, July 2024.
Proteoglycans are important multifunctional components of the central and peripheral nervous systems and represent a diverse group of specialized proteins that stabilize and functionalize these tissues. Abstract Central and peripheral nervous system (CNS/PNS) proteoglycans (PGs) have diverse functional roles, this study examined how these control ...
James Melrose
wiley   +1 more source

Sialoglycoproteins and sialyltransferases: Key regulators of blastocyst formation

Cells & Development
Following fertilization, there is an initial period of rapid cell division that leads to the formation of a multicellular structure known as the blastula, or blastocyst. Within this structure, sialic acids play a key role in influencing cellular processes such as signaling, cell-to-cell contact, and adhesion.
Douchez, Pélagie, Fliniaux, Ingrid, Takeda-Uchimura, Yoshiko, Marin, Matthieu, Martoriati, Alain, Harduin-Lepers, Anne, Cailliau, Katia   +6 more
openaire   +3 more sources

OMIP‐102: 50‐color phenotyping of the human immune system with in‐depth assessment of T cells and dendritic cells

Cytometry Part A, Volume 105, Issue 6, Page 430-436, June 2024.
Abstract We report the development of an optimized 50‐color spectral flow cytometry panel designed for the in‐depth analysis of the immune system in human blood and tissues, with the goal of maximizing the amount of information that can be collected using currently available flow cytometry platforms.
Andrew J. Konecny, Peter L. Mage, Aaron J. Tyznik, Martin Prlic, Florian Mair   +4 more
wiley   +1 more source

Isolated bladder exstrophy associated with a de novo 0.9 Mb microduplication on chromosome 19p13.12.

, 2013
The exstrophy-epispadias complex (BEEC) is a urogenital birth defect of varying severity. The causes of the BEEC are likely to be heterogeneous, with individual environmental or genetic risk factors still being largely unknown. In this study, we aimed to
Bartels, E., Boemers, T., Draaken, M., Ebert, A., Herrmann, B., Hoffmann, P., Ludwig, M., Moebus, S., Mughal, S., Nöthen, M., Pennimpede, T., Reutter, H., Rösch, W., Schmidt, D., Schmiedeke, E., Stein, R., Wittler, L., Wolter, S.   +17 more
core   +1 more source