Results 71 to 80 of about 2,977 (189)

Role of macrophage sialoadhesin in host defense against the sialylated pathogen group B Streptococcus [PDF]

, 2014
Several bacterial pathogens decorate their surfaces with sialic acid (Sia) residues within cell wall components or capsular exopolysaccharides. Sialic acid expression can promote bacterial virulence by blocking complement activation or by engagement of ...
Joshua Olson, Louie, Aaron, Crocker, Paul R., Victor Nizet, Aaron Louie, Ajit Varki, Paul R. Crocker, Varki, Ajit, Nizet, Victor, Yung-Chi Chang, Chang, Yung-Chi, Olson, Joshua   +11 more
core   +1 more source

CNS/PNS proteoglycans functionalize neuronal and astrocyte niche microenvironments optimizing cellular activity by preserving membrane polarization dynamics, ionic microenvironments, ion fluxes, neuronal activation, and network neurotransductive capacity

Journal of Neuroscience Research, Volume 102, Issue 7, July 2024.
Proteoglycans are important multifunctional components of the central and peripheral nervous systems and represent a diverse group of specialized proteins that stabilize and functionalize these tissues. Abstract Central and peripheral nervous system (CNS/PNS) proteoglycans (PGs) have diverse functional roles, this study examined how these control ...
James Melrose
wiley   +1 more source

Sialoglycoproteins and sialyltransferases: Key regulators of blastocyst formation

Cells & Development
Following fertilization, there is an initial period of rapid cell division that leads to the formation of a multicellular structure known as the blastula, or blastocyst. Within this structure, sialic acids play a key role in influencing cellular processes such as signaling, cell-to-cell contact, and adhesion.
Douchez, Pélagie, Fliniaux, Ingrid, Takeda-Uchimura, Yoshiko, Marin, Matthieu, Martoriati, Alain, Harduin-Lepers, Anne, Cailliau, Katia   +6 more
openaire   +3 more sources

Purification and characterization of 9-O-acetylated sialoglycoproteins from leukemic cells and their potential as immunological tool for monitoring childhood acute lymphoblastic leukemia [PDF]

, 2004
Sialic acids as terminal residues of oligosaccharide chains play crucial roles in several cellular recognition events. Exploiting the selective affinity of Achatinin-H toward N-acetyl-9-Oacetylneuraminic acid-a2-6-GalNAc, we have demonstrated the ...
Kohla, Guido, Isecke, Rainer, Merling, Anette, Schwartz-Albiez, Reinhard, Ghosh, Shyamasree, Bhattacharya, Dilip K, Bhattacharya, Dilip K., Mandal, Chhabinath, Schauer, Roland, Pal, Santanu, Brossmer, Reinhard, Mandal, Chitra   +11 more
core   +1 more source

OMIP‐102: 50‐color phenotyping of the human immune system with in‐depth assessment of T cells and dendritic cells

Cytometry Part A, Volume 105, Issue 6, Page 430-436, June 2024.
Abstract We report the development of an optimized 50‐color spectral flow cytometry panel designed for the in‐depth analysis of the immune system in human blood and tissues, with the goal of maximizing the amount of information that can be collected using currently available flow cytometry platforms.
Andrew J. Konecny, Peter L. Mage, Aaron J. Tyznik, Martin Prlic, Florian Mair   +4 more
wiley   +1 more source

Fractionation of sialoglycoproteins on an immobilized sialic acid-binding lectin

, 1981
Carcinoscorpin, the sialic acid-binding lectin from the horseshoe crab Carcinoscorpius rotunda cauda, has been immobilized using Sepharose. The immobilized lectin is shown to resolve the isoenzymes of alkaline phosphatase from sheep brain based on the ...
Dorai, D. Thambi, Bishayee, S., Bachhawat, B. K.   +2 more
core   +1 more source

Enhancing Sialidase Production from the Oerskovia paurometabola O129 Strain by the Optimization of Fermentation Parameters and the Addition of Stimulative Compounds

Applied Microbiology
Sialidases are gradually entering various areas of human practice—in medicine and pharmacy, as antiviral, antitumor, diagnostic, and vaccine preparations; for the chemoenzymatic synthesis of regioselective sialoglycoconjugates; and for the structural ...
Yana Gocheva, Ekaterina Krumova, Irina Lazarkevich, Rumyana Eneva, Stephan Engibarov   +4 more
doaj   +1 more source

Escherichia coli K1 RS218 Interacts with Human Brain Microvascular Endothelial Cells via Type 1 Fimbria Bacteria in the Fimbriated State [PDF]

, 2005
Escherichia coli K1 is a major gram-negative organism causing neonatal meningitis. E. coli K1 binding to and invasion of human brain microvascular endothelial cells (HBMEC) are a prerequisite for E.
Shin, S., Kim, K.J., di Cello, F., Cai, M., Khan, Naveed Ahmed, Xie, Y., Kim, K.S., Teng, C.H.   +7 more
core   +1 more source

Mobilization of lymphoblasts from Bone Marrow to Peripheral Blood in Childhood Acute Lymphoblastic Leukaemia: Role of 9-O-Acetylated Sialoglycoproteins

, 2012
Childhood acute lymphoblastic leukaemia is characterized by aberrant proliferation and accumulation of malignant lymphoblasts in bone marrow (BM), followed by their migration into circulation.
Reinhard Vlasak, Vlasak, Reinhard, Sarkara, Sayantani, Chandra, Sarmila, Chandan Mandal, Arup Kumar Bag, Sarkar, Sayantani, Suchandra Chowdhury, Chandrac, Sarmila, Sayantani Sarkar, Chowdhury, Suchandra, Baga, Arup Kumar, Bag, Arup Kumar, Chitra Mandal, Mandal, Chitra, Mandal, Chandan, Sarmila Chandra   +16 more
core   +1 more source

Top 52 cell surface sialoglycoproteins overexpressed in GBM tumor cells.

, 2014
aProteomic analysis of differential sialoglycoprotein expression in glioblastoma multiform (GBM) cells compared to astrocytes or neural progenitor cells (NPCs).
Steven A. Goldman (652727), Michael Smith (26855), Pascual Ferrara (479981), Denis Loyaux (479980), Philippe Fabre (652723), Sébastien Roudières (652720), Romane Auvergne (652725), Jean-Claude Guillemot (479982), Catherine Déon (652721), Vasudeo Badarinarayana (652726), Su Wang (191010), Paul August (652728), Sridaran Natesan (245186), Frédérique Guette (652722), François Autelitano (652719), Qinggong Ping (652724)   +15 more
core   +1 more source