Results 191 to 200 of about 21,169,060 (256)

Subunit structure of human erythrocyte glycophorin A.

Biochemistry, 1976
Glycophorin A is a sialoglycoprotein isolated from human erythrocyte membranes which seems to exist as stable dimeric complexes in the presence of sodium dodecyl sulfate. When analyzed by dodecyl sulfate acrylamide electrophoresis this molecule forms two PAS-stainable bands (PAS-U and PAS-2) which are reversibly interconvertible.
H. Furthmayr, V. Marchesi
semanticscholar   +3 more sources

Structural analysis of a membrane glycoprotein: glycophorin A.

Journal of Supramolecular Structure, 1977
AbstractGlycophorin A is the major sialoglycoprotein of the human erythrocyte membrane. Structural studies indicate that this molecule is made up of 3 domains composed of 2 hydrophilic segments which are separated by a region of 22 nonpolar amino acids.
H. Furthmayr
semanticscholar   +3 more sources

Quantification of glycophorin A and glycophorin B on normal human RBCs by flow cytometry

Transfusion, 2003
BACKGROUND: The quantification of antigens and proteins on RBCs has been achieved by different approaches. Flow cytometry allows the results of the earliest studies to be to reappraised because it offers the possibility of measuring the immunofluorescence intensity of single cells and integrating the individual data of a large number of cells within a ...
Bibiana D Riquelme
exaly   +3 more sources

Glycophorin a expression in malignant hematopoiesis

American Journal of Hematology, 1983
AbstractTwo hundred twenty‐nine patients with hematopoietic malignancies were tested for reactivity with a monoclonal anti‐human glycophorin A antibody. One hundred twenty‐three of these cases were classified as acute leukemias of either the myeloid, lymphoid, erythroid, or undifferentiated type.
K. Liszka, O. Majdic, P. Bettelheim, W. Knapp   +3 more
semanticscholar   +3 more sources

A novel Sta glycophorin produced via gene conversion of pseudoexon III from glycophorin E to glycophorin A gene

Human Mutation, 2000
Stone (St(a)) is a variant antigen carried on human erythrocyte MNSs glycophorins (GPSt(a)) that are genetically associated with splicing mutations in GPA genes or with hybrid formation between GPA and GPB genes. Here we identify the first and rare gene conversion event in which GPE, the third member of the family, recombined with GPA, giving rise to a
C H, Huang, Y, Chen, O O, Blumenfeld
openaire   +2 more sources

Glycophorin A: Band 3 aid

Blood Cells, Molecules, and Diseases, 2008
Band 3 (B3) is a major site of cytoskeletal attachment to the erythrocyte membrane and is important for gas exchange. A truncated isoform of B3 (kB3) is expressed in the alpha-intercalated cells of the kidney and its functional activity and basolateral localization are essential for acid secretion.
Williamson, RC, Toye, AM
openaire   +3 more sources

Monoclonal Antibodies Against Glycophorin A

Hybridoma, 1988
Two mouse IgM monoclonal antibodies, 177.1 and 179.3, are directed against glycophorin A, the major sialoglycoprotein of human erythrocytes. Both antibodies agglutinate blood group M and N erythrocytes equally well, both before and after treatment with neuraminidase or trypsin, but fail to agglutinate erythrocytes treated with papain.
K, Wasniowska, K R, Schroer, M, McGinniss, C, Reichert, D, Zopf   +4 more
openaire   +2 more sources

Characterization of alternatively spliced transcript variants of glycophorin A and glycophorin B genes in Chinese blood donors

Vox Sanguinis, 2022
AbstractBackground and ObjectivesThe molecular basis of MNS blood group variants is not fully clear yet. In this study, we have characterized mRNA variants of GYPA and GYPB genes to reveal whether alternative RNA splicing may cause antigenic diversity of the MNS system.Materials and MethodsTotal RNA was extracted from peripheral blood of Chinese blood ...
Yanlian Liang, Jianwei Ren, Fuling Zhong, Wenxu Hong, Yuqing Su, Fan Wu, Shuang Liang, Jun Liu, Shuanghua Fang, Yanwen Liang, Xiuchu Fan, Jiansuo Lin, Yi Liu, Bo Feng, Yunping Xu   +14 more
openaire   +2 more sources

Ultrastructure of a transmembrane glycoprotein, glycophorin A

Tissue and Cell, 1988
The major sialoglycoprotein of the human red cell membrane, glycophorin A, was isolated and examined by rotary shadowing and transmission electron microscopy. The glycophorin A molecule appeared as a cloud-like structure with a short, dense core within a large cloud.
G E, Wise, L X, Oakford, J K, Dzandu
openaire   +2 more sources

A family study of multiple mutations of alpha and delta glycophorins (glycophorins A and B)

Human Genetics, 1988
Glycophorins alpha and delta are the carriers of the antigens of the MNSs blood system; this report documents the presence of three glycophorin mutations in two individuals of a 16 member family. Erythrocytes were examined by serology, sodium dodecyl sulfate electrophoresis, and immunoblotting.
C H, Huang, K V, Puglia, W L, Bigbee, M L, Guizzo, M, Hoffman, O O, Blumenfeld   +5 more
openaire   +2 more sources