Results 81 to 90 of about 21,169,060 (256)
MMS22L is a novel key actor of normal and pathological erythropoiesis
Abstract The emergence of next‐generation sequencing techniques has led to the genetic characterization of numerous congenital erythroid disorders, emphasizing crucial pathways in both normal and pathological erythropoiesis. In this study, whole exome sequencing of a single patient with atypical congenital pure red cell aplasia revealed a mutation in ...
Elia Colin +31 more
wiley +1 more source
Erythroid anion transport, nitric oxide, and blood pressure
Glycophorin A and glycophorin B are structural membrane glycoproteins bound in the band 3 multiprotein complexes on human red blood cells (RBCs). Band 3 is an erythroid-specific anion exchanger (AE1).
Kate Hsu, Kate Hsu, Kate Hsu
doaj +1 more source
An ImmunoPEGliposome for Targeted Antimalarial Combination Therapy at the Nanoscale
Combination therapies, where two drugs acting through different mechanisms are administered simultaneously, are one of the most efficient approaches currently used to treat malaria infections.
Arnau Biosca +4 more
doaj +1 more source
Acquired Elliptocytosis as a Manifestation of Myelodysplastic Syndrome with Ring Sideroblasts and Multilineage Dysplasia. [PDF]
Acquired elliptocytosis is a known but rarely described abnormality in the myelodysplastic syndromes (MDS). Here we report the case of an elderly male who was admitted to the hospital with chest pain, dyspnea, and fatigue and was found to be anemic with ...
Dwyre, Denis M +2 more
core +2 more sources
Deoxynivalenol induces anemia by disrupting hematopoietic homeostasis and impairing erythroid lineage commitment and differentiation via ribosomal stress–mediated G1/S cell cycle arrest. GDF15 supplementation alleviates this arrest through the β‐catenin–Myc–p21 signaling axis, highlighting GDF15 as a potential therapeutic target for DON‐induced ...
Yan Li +12 more
wiley +1 more source
Background Autologous blood transfusion is one of the illicit strategies, banned by the World Anti-Doping Agency, to increase the levels of hemoglobin, with a consequent improvement in the delivery of oxygen to tissues.
Giorgia M. Biasini +3 more
doaj +1 more source
Granulocytic sarcoma (chloroma) of the oral cavity: Report of a case and literature review [PDF]
SummaryA case of granulocytic sarcoma (chloroma) of the palatal mucosa is reported. Granulocytic sarcomas are composed of a localized collection of immature myeloid cells and are considered to be specific lesions of AML or the onset of a blast crisis in ...
M.J. Koudstaal +55 more
core +1 more source
Blood group O expression in normal tissues and tumors
The H antigen (O blood group), the precursor to A and B blood groups, is expressed on human erythrocytes. However, reliable reagents for H antigen detection are lacking. We generated two novel monoclonal antibodies using sea lamprey immunization, Tn4‐31L and OmcFL3‐02, that specifically detect the H antigen on glycan microarrays, glycoproteins, and ...
Ea Kristine Clarisse Tulin +11 more
wiley +1 more source
Erythrocyte binding peptides: a story in the search for a malaria vaccine [PDF]
Merozoite invasion of erythrocytes relies on molecular interactions between parasite and host proteins, making these proteins potential therapeutic targets.
Mauricio Urquiza-Martinez +2 more
doaj +1 more source
Flowcytometric assessment of fetomaternal hemorrhage during external cephalic version at term [PDF]
External cephalic version (ECV) at term is a safe procedure and reduces the incidence of cesarean sections for breech presentation. One of the known complications, however, is an ECV-related disruption of the placental barrier and a subsequent ...
Friese, Klaus +6 more
core +2 more sources

