Results 161 to 170 of about 964,671 (415)

Hepatitis C virus (HCV) infection may elicit neutralizing antibodies targeting epitopes conserved in all viral genotypes [PDF]

, 2009
Anti-hepatitis C virus (HCV) cross-neutralizing human monoclonal antibodies, directed against conserved epitopes on surface E2 glycoprotein, are central tools for understanding virus-host interplay, and for planning strategies for prevention and ...
Arvind H. Patel, Giovanni Nitti, Giuseppe Sautto, Jonathan K. Ball, Mario Perotti, Massimo Clementi, Nicasio Mancini, Nicola Clementi, Roberta A. Diotti, Roberto Burioni, Sung Key Jang   +10 more
core   +5 more sources

Graded Hydroxyapatite Triply Periodic Minimal Surface Structures for Bone Tissue Engineering Applications

Advanced Healthcare Materials, EarlyView.
This study investigates the role of triply periodic minimal structures in load bearing bone tissue engineering applications. Research uses a combination of mechanical testing, material characterization, and in vitro tests to study the impact of TPMS lattice structures (gyroid, lidinoid and split‐P).
Tejas M. Koushik, Catherine M. Miller, Elsa Antunes   +2 more
wiley   +1 more source

Advances in Glycoprotein Synthesis

ChemInform, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Clay S. Bennett, Chi-Huey Wong, Lei Liu
openaire   +3 more sources

TbGT8 is a bifunctional glycosyltransferase that elaborates N-linked glycans on a protein phosphatase AcP115 and a GPI-anchor modifying glycan in Trypanosoma brucei [PDF]

, 2014
The procyclic form of Trypanosoma brucei expresses procyclin surface glycoproteins with unusual glycosylphosphatidylinositol-anchor side chain structures that contain branched N-acetyllactosamine and lacto-N-biose units.
Acosta-Serrano, Alexander, Bakalara, Bangs, Ferguson, Guther, Guther, Hiroshi Nomoto, Ioffe, Izquierdo, Izquierdo, Kazunori Hashida, Kelley, Kobata, Mami Hino, Masayuki Nakanishi, Mehlert, Mehlert, Mehlert, Mehlert, Michael A.J. Ferguson, Moe Karasudani, Nagamune, Nolan, Oguri, Parussini, Pierleoni, Roper, Schiller, Schwartz, Stanley, Strang, Takahiro Shiraishi, Treumann, Vassella, Wirtz, Zamze   +36 more
core   +2 more sources

“Therapies Through Gut:” Targeted Drug Delivery for Non‐Gastrointestinal Diseases by Oral Administration

Advanced Healthcare Materials, EarlyView.
Schematic illustration of the mechanism of targeted delivery of nanoparticles including 1) paracellular, 2) endolysosomal escape, 3) receptor mediated endocytosis, and 4) M cell mediated transport for non‐GI diseases by oral administration such as atherosclerosis, cancer, diabetes, and brain diseases. Abstract Oral drug delivery is a promising approach
Subarna Ray, Shehzahdi S. Moonshi, Hang Thu Ta   +2 more
wiley   +1 more source

Spatiotemporal Expression of Pregnancy-Specific Glycoprotein Gene rnCGMl in Rat Placenta [PDF]

, 1993
As a basis towards a better understanding of the role of the pregnancy-specific glycoprotein (PSG) family in the maintenance of pregnancy, detailed investigations are described on the expression of a recently identified rat PSG gene (rnCGM1) at the mRNA ...
Lucas, Kurt, Rebstock, Sabine, Thompson, John A., Weiss, Martina, Zimmermann, Wolfgang   +4 more
core   +1 more source

Reservoir‐Type Subcutaneous Implantable Devices Containing Porous Rate Controlling Membranes for Sustained Delivery of Risperidone

Advanced Healthcare Materials, EarlyView.
This study presents a novel implantable drug delivery systemwith a biodegradable poly(caprolactone) membrane and compressed drug core forsustained release. These implantable devices deliver risperidone in vitro for 170 days and in vivo for 49 days in rats, showing promise for chronic conditions like schizophrenia.
Linlin Li, Andi Dian Permana, Juan Domínguez‐Robles, Muh Nur Amir, Habibie Habibie, Qonita Kurnia Anjani, Li Zhao, Natalia Moreno‐Castellanos, Ryan F Donnelly, Eneko Larrañeta   +9 more
wiley   +1 more source

On the Carbohydrate Components of the alpha1-Acid Glycoprotein of Human Plasma. [PDF]

, 1956
Ikuo Yamashina, F. Heijkenskjöld, Bengt Aurivillius, N. A. Eliasson, B. Thorell   +4 more
openalex   +1 more source

Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein

Cell, 2020
A. Walls, Young-Jun Park, M. Alexandra Tortorici, A. Wall, Andrew T. McGuire, D. Veesler   +5 more
semanticscholar   +1 more source

The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors.

Journal of Clinical Investigation, 1998
Currently available HIV-1 protease inhibitors are potent agents in the therapy of HIV-1 infection. However, limited oral absorption and variable tissue distribution, both of which are largely unexplained, complicate their use.
R. Kim, M. Fromm, C. Wandel, B. Leake, A. J. Wood, D. Roden, G. Wilkinson   +6 more
semanticscholar   +1 more source