Results 261 to 270 of about 1,005,229 (334)

Venezuelan Equine Encephalitis Virus: Structural Biology, Vaccines, and Advances in Functional Antibodies. [PDF]

Vaccines (Basel)
Tang R, Wang D, Chen G, Liu C, Zhang L, Peng F, Yu J, Li X, Luo H, Wen Y, Qiao C.   +10 more
europepmc   +1 more source

SAR Studies on Tetrahydroisoquinoline Derivatives: The Role of Flexibility and Bioisosterism To Raise Potency and Selectivity toward P-glycoprotein

, 2014
Elena Capparelli, Laura Zinzi, Mariangela Cantore, Marialessandra Contino, Maria Grazia Perrone, Gert Luurtsema, Francesco Berardi, Roberto Perrone, Nicola Antonio Colabufo   +8 more
openalex   +1 more source

Evolution of Multivalent Aptamer Corona for High‐Throughput Multiplexed Detection of Multiple Cancers

Advanced Science, EarlyView.
A multivalent aptamer corona is evolved via established ProteoFish‐SELEX (systematic evolution of ligands by exponential enrichment) for high‐throughput multiplexed detection of multiple cancers. Clinical validation using multivalent aptamer corona demonstrated high accuracy and specificity in multiplexed detection of ovarian, lung, and colorectal ...
Mengjie Wang, Baichuan Jin, Xin Dai, Haozhe Huang, Qiqi Liu, Jianqing Zhu, Haixing Ju, Qixun Chen, Yongmei Song, Weihong Tan, Yuan Liu   +10 more
wiley   +1 more source

LRP1 Interacts with the Rift Valley Fever Virus Glycoprotein Gn via a Calcium-Dependent Multivalent Electrostatic Mechanism. [PDF]

Biomolecules
Yang H, Chen H, Jiang W, Yan R.
europepmc   +1 more source

Large-scale purification of functional human P-glycoprotein (ABCB1)

, 2019
Krishnamachary Nandigama, Sabrina Lusvarghi, Suneet Shukla, Suresh V. Ambudkar   +3 more
openalex   +2 more sources

Advanced Human Immune Cell‐Organoid Co‐Cultures for Functional Testing of Cancer Nanovaccines

Advanced Science, EarlyView.
Pancreatic ductal adenocarcinoma remains difficult to treat. We establish an organoid–immune co‐culture using patient‐derived organoids and matched T‐cells to assess cancer vaccines. A mesothelin‐targeted nanovaccine activates antigen‐specific T‐cells, increases IFN‐γ, and targets MSLN+ organoids.
Nathalia Ferreira, David Agorku, Andre Rosa, Julia Roosz, Lena Christ, Nicole Anderle, Ajinkya Kulkarni, Abir Hussein, Sana S. Sayedipour, Omar F. Luna, Tobias Legler, Philipp Ströbel, Fernando Albericio, Luis Cruz, Phillipp Beckhove, Peter Loskill, Frauke Alves, M. Andrea Markus, Fernanda Ramos‐Gomes   +18 more
wiley   +1 more source

Elevator‐Like Hollow Channels in Porous Scaffolds Accelerate Vascularized Bone Regeneration via NETs‐Fibrin‐Mediated Macrophage Recruitment

Advanced Science, EarlyView.
This study demonstrates that how hollow‐channel scaffolds promote vascularized bone regeneration via an immunomodulatory mechanism. The channel structures facilitate the formation of a neutrophil extracellular traps‐fibrin scaffold that recruits vascular endothelial growth factor A (VEGF‐A)‐secreting M2 macrophages to drive angiogenesis. Combining this
Guifang Wang, Rongpu Liu, Huijing Ma, Shuhan Duan, Guangzheng Yang, LingXi Meng, Yuqin Qiao, Dongqiang Song, Wenjie Zhang   +8 more
wiley   +1 more source

Effect of hypokalemia on renal expression of the ammonia transporter family members, Rh B Glycoprotein and Rh C Glycoprotein, in the rat kidney

, 2011
Ki‐Hwan Han, Hyun‐Wook Lee, Mary E. Handlogten, Jesse M. Bishop, Moshe Levi, Jin Kim, Jill W. Verlander, I. David Weiner   +7 more
openalex   +2 more sources

GbWAKL20 Phosphorylates GbNFYB8 to Modulate Verticillium Wilt Resistance in Cotton

Advanced Science, EarlyView.
Wall‐associated receptor‐like kinases (WAKLs) play pivotal roles in extracellular–intracellular signal transduction. Upon sensing Verticillium dahliae infestation at the plasma membrane, GbWAKL20 accumulates and transmits signals to the nucleus via endoplasmic reticulum‐mediated Golgi vesicle transport.
Guilin Wang, Qingxin Si, Zhiguo Chen, Zhe Yu, Zhan Guo, Lu Wang, Weixi Li, Wangzhen Guo   +7 more
wiley   +1 more source

Potential of Bovine Herpesvirus Vectors for Recombinant Vaccines. [PDF]

Vaccines (Basel)
Gokduman EM, Atasoy MO, Goksu AG, Sozdutmaz İ, Munir M.   +4 more
europepmc   +1 more source