Correction: Jarahian et al. Re-Expression of Poly/Oligo-Sialylated Adhesion Molecules on the Surface of Tumor Cells Disrupts Their Interaction with Immune-Effector Cells and Contributes to Pathophysiological Immune Escape. <i>Cancers</i> 2021, <i>13</i>, 5203. [PDF]
Jarahian M+5 more
europepmc +1 more source
24p3R is an astrocytic receptor for α‐Syn uptake. When LCN2 is secreted from astrocytes, it binds to its receptor 24p3R in astrocytes and this binding impedes the α‐Syn PFF binding to 24p3R. This in turn inhibits 24p3R‐mediated α‐Syn PFF uptake and reduces the clearance of extracellular α‐Syn by astrocytes, which contributes to α‐Syn spread and ...
Ying‐Ying Jiao+14 more
wiley +1 more source
Human Milk Oligosaccharides Multivalently Presented on Defined Synthetic Neo-Glycoproteins Are Nanomolar Ligands of Tandem-Repeat Galectins. [PDF]
Červený J+17 more
europepmc +1 more source
Changes of Glycoprotein Metabolism in Aging and Arteriosclerosis
Kiyoaki Ito
openalex +2 more sources
Human Schlafen 14 Cleavage of Short Double‐Stranded RNAs Underpins its Antiviral Activity
SLFN14 is associated with human diseases. SLFN14 is found to cleave RNAs containing short duplexes. The cryo‐EM structures of SLFN14 and SLFN14‐hairpin RNA complex reveal that SLFN14 assembles into a ring‐like dimer; two RNase domains form an RNA‐binding groove accommodating a hairpin RNA.
Mengyun Li+8 more
wiley +1 more source
Insights into the antiviral mechanisms of β-caryophyllene: inhibiting viral spread and its synergy with acyclovir. [PDF]
Yasaghi M+5 more
europepmc +1 more source
Changes of Glycoproteins in Normal, Obese, and Arteriosclerotic Subjects
相澤 豊三+4 more
openalex +2 more sources
A Prion‐Like Domain in EBV EBNA1 Promotes Phase Separation and Enables SRRM1 Splicing
This study discoveries that EBV EBNA1 behaves as a prion‐like protein, verified using cell‐based assays and the Saccharomyces cerevisiae Sup35p prion identification system. The prion‐like domain of EBNA1 drives liquid–liquid phase separation. EBNA1 interacts with the splicing factor SRSF1 to regulate the expression of the SRRM1 splicing isoforms ...
Xiaoyue Zhang+17 more
wiley +1 more source
Insights into the Landscape of Alphavirus Receptor and Antibody Interactions. [PDF]
Poudyal S, Bandyopadhyay A, Kuhn RJ.
europepmc +1 more source
This study presents a comprehensive data mining strategy for in‐depth extraction of overall and altered glycan features from structural and site‐specific glycoproteome data across various biomedical samples. The strategy enables the uncovery of four major altered glycan features associated with thymic involution and reveals their coordinated ...
Zhida Zhang+11 more
wiley +1 more source