Results 1 to 10 of about 69,901 (250)
Annotation and comparative analysis of the glycoside hydrolase genes in
Background Glycoside hydrolases cleave the bond between a carbohydrate and another carbohydrate, a protein, lipid or other moiety. Genes encoding glycoside hydrolases are found in a wide range of organisms, from archea to animals, and are relatively ...
Wu Jiajie +5 more
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Proteomic analysis of a novel Bacillus Jumbo phage revealing glycoside hydrolase as structural component [PDF]
Tailed phages with genomes of larger than 200 kbp are classified as Jumbo phages and exhibited extremely high uncharted diversity. The genomic annotation of Jumbo phage is often disappointing because most of the predicted proteins, including structural ...
Yihui eYuan, Meiying eGao
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Background Metabolism of carbon bound in wheat arabinoxylan (WAX) polysaccharides by bacteria requires a number of glycoside hydrolases active toward different bonds between sugars and other molecules.
Brady D. Lee +3 more
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Functional metagenomics reveals novel β-galactosidases not predictable from gene sequences. [PDF]
The techniques of metagenomics have allowed researchers to access the genomic potential of uncultivated microbes, but there remain significant barriers to determination of gene function based on DNA sequence alone.
Jiujun Cheng +6 more
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Increase of intestinal bacterial sialidase activity exacerbates acute colitis in mice
The availability of endogenous and dietary carbohydrates in the gastrointestinal tract influences the composition of the gut microbiota. Carbohydrate foraging requires the action of bacterially-encoded glycoside hydrolases, which release mono- and ...
Tobias Hasler +7 more
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Mechanism of cooperative N-glycan processing by the multi-modular endoglycosidase EndoE
EndoE is a multi-domain glycoside hydrolase of the human pathogen Enterococcus faecalis. Here, the authors present crystal structures of EndoE and provide biochemical insights into the molecular basis of EndoE’s substrate specificity and catalytic ...
Mikel García-Alija +12 more
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Bioprospecting for bacteria producing glycoside hydrolases with potential biotechnological applications [PDF]
Glycoside hydrolases are a diverse group of enzymes that act on various α-glucans, exhibiting distinct product specificities. Bioprospecting for bacteria capable of producing novel glycoside hydrolases represents a significant area of interest in ...
JULIETA DE LAS MERCEDES CASTILLO +2 more
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Most Gram-negative bacteria synthesize osmo-regulated periplasmic glucans (OPG) in the periplasm or extracellular space. Pathogenicity of many pathogens is lost by knocking out opgG, an OPG-related gene indispensable for OPG synthesis.
Sei Motouchi +3 more
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Background The combination of cellulase and lytic polysaccharide monooxygenase (LPMO) is known to boost enzymatic saccharification of cellulose. Although the synergy between cellulases (GH5, 6 or 7) and LPMOs (AA9) has been extensively studied, the ...
Xing Qin +9 more
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Structural basis of product inhibition by arabinose and xylose of the thermostable GH43 β-1,4-xylosidase from Geobacillus thermoleovorans IT-08. [PDF]
Complete degradation of the xylan backbone of hemicellulosic plant cell walls requires the synergistic action of endo-xylanases and β-1,4-xylosidases.
Ali Rohman +3 more
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