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Bioactive microbial metabolites from glycyrrhetinic acid

Phytochemistry, 2010
Biotransformation of 18beta-glycyrrhetinic acid, using Absidia pseudocylinderospora ATCC 24169, Gliocladium viride ATCC 10097 and Cunninghamella echinulata ATCC 8688a afforded seven metabolites, which were identified by different spectroscopic techniques (1H, 13C NMR, DEPT, 1H-1H COSY, HMBC and HMQC). Three of these metabolites, viz.
Maatooq, Galal T.   +3 more
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Metabolism of Glycyrrhetinic Acid in Human Subjects

Nature, 1954
IN a series of publications Groen, Pelser, Frenkel, Kamminga and Willebrands1–6 have reported on the successful treatment of Addison's disease by extract of liquorice, glycyrrhizinic acid or glycyrrhetinic acid. It was shown that either the crude liquorice extract or its active component produced an effect on electrolyte metabolism which was entirely ...
V M, VAN KATWIJK, L G, HUIS IN'T VELD
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Selective inhibition of 11β-hydroxysteroid dehydrogenase 1 by 18α-glycyrrhetinic acid but not 18β-glycyrrhetinic acid

The Journal of Steroid Biochemistry and Molecular Biology, 2009
Elevated cortisol concentrations have been associated with metabolic diseases such as diabetes type 2 and obesity. 11beta-hydroxysteroid dehydrogenase (11beta-HSD) type 1, catalyzing the conversion of inactive 11-ketoglucocorticoids into their active 11beta-hydroxy forms, plays an important role in the regulation of cortisol levels within specific ...
Classen-Houben, D.   +6 more
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Prolonged Administration of Glycyrrhetinic Acid in Rats

Journal of Pharmaceutical Sciences, 1964
Prolonged administration of glycyrrhetinic acid was studied in immature female rats, castrated male donor parabionts, and mature cyclic rats. Glycyrrhetinic acid treatment for 7 days interfered with the uterotrophic response of immature rats to estradiol benzoate but had no effect on the pituitary-ACTH content.
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Glycyrrhetinic Acid

BMJ, 1960
E. E. Turner, R. T. Williams
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Glycyrrhetinic Acid

2018
Wen Zhang, Qi-Meng Zhou, Guan-Hua Du
openaire   +1 more source

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