Results 91 to 100 of about 10,445 (254)

Extraction of Glycyrrhizic Acid from Glycyrrhiza uralensis Using Ultrasound and Its Process Extraction Model

open access: yesApplied Sciences, 2016
This work focused on the intensification of extraction process of glycyrrhizic acid (GA) from Glycyrrhiza uralensis using ultrasound-assisted extraction (UAE) method.
Jiangqing Liao, Baida Qu, Nan Zheng
doaj   +1 more source

Current Status of Herbal Medicines in Chronic Liver Disease Therapy: The Biological Effects, Molecular Targets and Future Prospects [PDF]

open access: yes, 2015
Chronic liver dysfunction or injury is a serious health problem worldwide. Chronic liver disease involves a wide range of liver pathologies that include fatty liver, hepatitis, fibrosis, cirrhosis, and hepatocellular carcinoma.
Feng, Y   +5 more
core   +2 more sources

Impact of C18 Epimerization of Indole‐ and Pyrazole‐Fused 18β‐Glycyrrhetinic Acid Derivatives on PTP1B and TCPTP Inhibitory Activity: Synthesis, In Vitro, and In Silico Studies

open access: yesChemMedChem, Volume 20, Issue 22, November 18, 2025.
The indole derivative (FC‐114) and the N‐phenylpyrazole (FC‐122) of glycyrrhetinic acid are both potent inhibitors of the Protein Tyrosine Phosphatase 1B, with IC50 values of 0.48 μM and 1.15 μM, respectively. However, their activity decreases by up to four times when the 18β‐H position is epimerized to 18α‐H or when the carbonyl group at the C11 ...
Ledy De‐la‐Cruz‐Martínez   +10 more
wiley   +1 more source

Mutation in the pssZ Gene Negatively Impacts Exopolysaccharide Synthesis, Surface Properties, and Symbiosis of Rhizobium leguminosarum bv. trifolii with Clover [PDF]

open access: yes, 2018
Rhizobium leguminosarum bv. trifolii is a soil bacterium capable of establishing a nitrogen-fixing symbiosis with clover plants (Trifolium spp.). This bacterium secretes large amounts of acidic exopolysaccharide (EPS), which plays an essential role in ...
Janczarek, Monika   +4 more
core   +1 more source

Oleanane-type Triterpene Glycosides from Glycyrrhiza Uralensis [PDF]

open access: yesNatural Product Communications, 2007
Chemical investigation of the roots of Glycyrrhiza uralensis resulted in the isolation of six oleanane-type triterpene glycosides (1 – 6), including one new saponin (1) and two (2 and 3) obtained as natural products for the first time. The new licorice saponin (1) was identified as 22β–acetoxylglycyrrhizin from [α]D, mass spectrometric, and UV, IR ...
Jinwei Li-Yang   +4 more
openaire   +1 more source

Medicine‐Food Plant Polysaccharides Modulate Diabetes and Diabetic Complications Through Maintaining Gut Function: A Review

open access: yesFood Frontiers, Volume 6, Issue 6, Page 2720-2765, November 2025.
Polysaccharides derived from medicine‐food plants restore intestinal barrier integrity and microbiota balance while modulating short‐chain fatty acid levels. These modifications significantly alleviate diabetes and its complications, including nephropathy, retinopathy, cardiovascular disease, and neuropathy.
Yi Long   +13 more
wiley   +1 more source

Antimicrobial Effects against Oral Pathogens and Cytotoxicity of Glycyrrhiza uralensis Extract

open access: yesPlants, 2020
We aimed to evaluate the antimicrobial effects of Glycyrrhiza uralensis extract on Streptococcus mutans and Candida albicans and its biocompatibility for dental applications. The antimicrobial activity of the G. uralensis extracts at concentrations of 50,
Song-Yi Yang   +3 more
doaj   +1 more source

Spatio-Temporal Selection of Reference Genes in the Two Congeneric Species of \u3ci\u3eGlycyrrhiza\u3c/i\u3e [PDF]

open access: yes, 2021
Glycyrrhiza, a genus of perennial medicinal herbs, has been traditionally used to treat human diseases, including respiratory disorders. Functional analysis of genes involved in the synthesis, accumulation, and degradation of bioactive compounds in these
An, Yu   +7 more
core   +1 more source

Antioxidant and Anti-Melanogenic Activities of Heat-Treated Licorice (Wongam, Glycyrrhiza glabra × G. uralensis) Extract [PDF]

open access: gold, 2021
Min Hye Kang   +6 more
openalex   +1 more source

Ononin, a Natural Isoflavone Glycoside, Alleviates Postoperative Cognitive Dysfunction in Aged Mice by Regulating Neuroinflammation and Oxidative Stress

open access: yesBrain and Behavior, Volume 15, Issue 10, October 2025.
Ononin alleviates postoperative cognitive dysfunction in aged mice by regulating neuroinflammation and oxidative stress. ABSTRACT Objective Postoperative cognitive dysfunction (POCD) is a serious neurological complication that currently lacks effective clinical prevention and treatment.
Ming Li   +7 more
wiley   +1 more source

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