Results 211 to 220 of about 9,008 (236)

Effect of Glycyrrhizic Acid on Lappaconitine Phototransformation

The Journal of Physical Chemistry B, 2007
1H NMR and CIDNP methods were used to demonstrate that triterpene glycoside (glycyrrhizic acid, GA) can substantially change the efficiency and direction of phototransformation of alkaloid lappaconitine (LA) due to both its solubilization in GA micelles and protonation of LA amine nitrogen in water-alcohol solutions.
Valeria S. Kornievskaya, Alexander I. Kruppa, Nicholas E. Polyakov, Tatyana V. Leshina   +3 more
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Advances in Pharmacological Activities and Mechanisms of Glycyrrhizic Acid

Current Medicinal Chemistry, 2020
Licorice (Glycyrrhiza glabra L.) is widely regarded as an important medicinal plant and has been used for centuries in traditional medicine because of its therapeutic properties. Studies have shown that metabolites isolated from licorice have many pharmacological activities, such as antiinflammatory, anti-viral, participation in immune regulation ...
Kun Chen, Rong Yang, Fa-Qian Shen, Hai-Liang Zhu   +3 more
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[Preparation of evodiamine-glycyrrhizic acid micelles with glycyrrhizic acid as carrier and their anti-hepatic fibrosis activity].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2020
This study aimed to prepare evodiamine-glycyrrhizic acid(EVO-GL) micelles to enhance the anti-hepatic fibrosis activity of evodiamine. Firstly, EVO-GL micelles were prepared with use of thin film dispersion method. With particle size, encapsulation efficiency, loading capacity of micelles and the solubility of evodiamine as the indexes, the effect of ...
Yingguang Deng, Yaolu Zhu, Shichang Zhang, Lyu Xueli, Guofeng Li, Boxin Zhao, Sijia Liu   +6 more
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Glycyrrhizic acid and its hydrolysate as mineralocorticoid agonist

Journal of Steroid Biochemistry, 1987
Mineralocorticoid activity of glycyrrhetinic acid (GR) was studied in vivo (electrical potential difference in rat rectum) and in vitro (brush border Mg2+-HCO3- ATPase in rat small intestine, kidney cytosol binding of GR with and without RU-28362, anti-glucocorticoid compound) in order to clarify the mechanism of mineralocorticoid-like activity of GR ...
R, Takeda, I, Miyamori, R, Soma, T, Matsubara, M, Ikeda   +4 more
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New Amino-Acid Conjugates of Glycyrrhizic Acid

Chemistry of Natural Compounds, 2014
New conjugates of glycyrrhizic acid (GA) containing two amino-acid methyl esters (4-aminobutanoic, 6-aminohexanoic, 11-aminoundecanoic) were synthesized by the activated-ester method using N-hydroxysuccinimide (HOSu)-N,N′-dicyclohexylcarbodiimide (DCC).
L. A. Baltina, O. V. Stolyarova, L. A. Baltina, R. M. Kondratenko, V. A. Fedorova, Ya. A. Orshanskaya, V. V. Zarubaev   +6 more
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Membrane-modifying activity of glycyrrhizic acid

Russian Chemical Bulletin, 2015
Owing to amphiphilicity, glycyrrhizic acid is capable of forming complexes with a variety of hydrophobic therapeutic compounds. This is accompanied by a significant decrease in the therapeutic dose of the drug. In addition, glycyrrhizic acid has a strong influence on the permeability and elasticity of cell membranes.
O. Yu. Selyutina, O. Yu. Selyutina, Nikolay E. Polyakov, I. E. Apanasenko, I. E. Apanasenko   +4 more
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Research Progress of Glycyrrhizic Acid on Antiviral Activity

Mini-Reviews in Medicinal Chemistry, 2019
Glycyrrhizic acid (GA), a triterpene isolated from the roots and rhizomes of licorice, named Glycyrrhiza glabra, is the principal bioactive ingredient of anti-viral, anti-inflammatory and hepatoprotective effects. GA has been used in the clinical treatment of hepatitis, bronchitis, gastric ulcer, AIDS (acquired immunodeficiency syndrome), certain ...
Na Lu, Hai-Liang Zhu, Yong-An Yang, Zhi-Gang Sun, Ting-Ting Zhao   +4 more
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Isolating and Purification Technologies for Glycyrrhizic Acid

Journal of Separation Science
ABSTRACTGlycyrrhizic acid (GA) is the primary active component of the traditional Chinese medicinal herb licorice. It possesses antimicrobial, anti‐inflammatory, and antitumor activities. In addition, due to its unique sweetness, it can also be used as a food additive. Traditional Chinese medicines are typically used directly as drugs.
Meng, Zhao, Qing, Wang, Yun, Yang, Lanlan, Sun, Xue-Song, Gu, Chang-Jiang-Sheng, Lai   +5 more
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Glycyrrhizic acid in liquorice—Evaluation of health hazard

Food and Chemical Toxicology, 1993
Literature on case reports, clinical studies and biochemical mechanisms of the sweet-tasting compound glycyrrhizic acid in liquorice was critically reviewed to provide a safety assessment of its presence in liquorice sweets. A high intake of liquorice can cause hypermineralocorticoidism with sodium retention and potassium loss, oedema, increased blood ...
R. Reistad, Jan Alexander, F.C. Størmer
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Development of an enzyme‐linked immunosorbent assay and immunoaffinity chromatography for glycyrrhizic acid using an anti‐glycyrrhizic acid monoclonal antibody

Journal of Separation Science, 2015
In this work, a new monoclonal antibody specific for glycyrrhizic acid was prepared and characterized. A hybridoma secreting an anti‐glycyrrhizic acid monoclonal antibody was produced by fusing splenocytes from a mouse immunized against a glycyrrhizic acid–bovine serum albumin conjugate with the hypoxanthine–aminopterin–thymidine‐sensitive mouse ...
Yue, Zhang, Huihua, Qu, Wenhao, Zeng, Yan, Zhao, Wenchao, Shan, Xueqian, Wang, Qingguo, Wang, Yan, Zhao   +7 more
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