Results 221 to 230 of about 9,008 (236)
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Antiviral Properties of Glycyrrhizic Acid and its Semisynthetic Derivatives
Mini-Reviews in Medicinal Chemistry, 2009Some natural triterpenes exert a definite antiviral activity on several human viruses. New synthetic derivatives of glycyrrhizic acid (GL) are even more active than the parental molecule. GL can alter the expression of viral genes involved in cell transformation, thus opening a new window for speculating on viral cancerogenesis.
POMPEI, RAFFAELLO +2 more
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Intermolecular Voids in Lipid Bilayers in the Presence of Glycyrrhizic Acid
The Journal of Physical Chemistry B, 2018It is known that glycyrrhizic acid (GA) promotes the enhancement of the activity of several medicines. This is attributed to the fact that GA increases the membrane permeability of small drug molecules. There is an opinion that GA facilitates the formation of additional large voids in the membrane, which enhance the passive diffusion of molecules ...
Ekaterina A. Shelepova +3 more
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Pharmaceutical Development and Technology
The purpose of this study was to investigate the impact of glycyrrhizic acid (GL) concentrations on in vitro and in vivo behavior of quercetin (QT) nanocrystals stabilized by GL (QT-NCs/GL), with a particular focus on its influence on liver targeted drug delivery.
Wang, Fengxia +5 more
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The purpose of this study was to investigate the impact of glycyrrhizic acid (GL) concentrations on in vitro and in vivo behavior of quercetin (QT) nanocrystals stabilized by GL (QT-NCs/GL), with a particular focus on its influence on liver targeted drug delivery.
Wang, Fengxia +5 more
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The Anti‐Angiogenic Activities of Glycyrrhizic Acid in Tumor Progression
Phytotherapy Research, 2012Glycyrrhizic acid (GA) is the bioactive compound of licorice and has been used as a herbal medicine because of its anti‐viral, anti‐cancer, and anti‐inflammatory properties. This study was designed to investigate the effects of GA on tumor growth, angiogenesis, and the mechanisms underlying the anti‐angiogenic activities of GA.
Kyu-Won Kim +3 more
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Azathioprine hepatotoxicity and the protective effect of liquorice and glycyrrhizic acid
Phytotherapy Research, 2006AbstractThis study aimed to evaluate the responses of human hepatocytes to azathioprine hepatotoxicity in comparison with the well‐studied azathioprine hepatotoxicity in rat hepatocytes and the effects of protective agents to suppress azathioprine hepatotoxicity.
Chong Shen +4 more
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International Journal of Toxicology, 2007
Glycyrrhetinic Acid and its salts and esters and Glycyrrhizic Acid and its salts and esters are cosmetic ingredients that function as flavoring agents or skin-conditioning agents—miscellaneous or both. These chemicals may be isolated from licorice plants.
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Glycyrrhetinic Acid and its salts and esters and Glycyrrhizic Acid and its salts and esters are cosmetic ingredients that function as flavoring agents or skin-conditioning agents—miscellaneous or both. These chemicals may be isolated from licorice plants.
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Effects of Glycyrrhizae and Glycyrrhizic Acid on Radiation Injury in Mice
The American Journal of Chinese Medicine, 1996The effects of Glycyrrhizae (GL) and Glycyrrhizic acid (GA) on promoting the recovery of mice from radiation injury were investigated. Two hundred ICR strain male mice, 6-8 weeks old, were randomly divided into four groups. Group A was the normal control. Group B, the experimental control, was treated with 4 Gy γ-ray irradiation.
I-Hsin Lin +3 more
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Isolation and purification of glycyrrhizic acid with solvent extraction
Separation and Purification Technology, 2005Solvent extraction of glycyrrhizic acid (GA) from liquorice leaching solution was studied with tributyl phosphate, trialkylphosphine oxide, n-hexanol and 2-ethyl-hexanol as extractants. The results showed that GA was easily extracted into the organic phase in molecular state by the formation of hydrogen bond.
Guoguang Niu +3 more
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Self-Association of Glycyrrhizic Acid. NMR Study
Zeitschrift für Physikalische Chemie, 2016Abstract The use of various NMR techniques allows to demonstrate the aggregation processes of β-glycyrrhizic acid (GA) in water/methanol (4:1, v:v) mixture with solution pH≤5. The micelle formation was monitored by measuring T2 relaxation and diffusion of GA. The model of gelation from micelles was suggested.
Alexander I. Kruppa +3 more
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Pharmacological properties of novel glycopeptides of glycyrrhizic acid
Pharmaceutical Chemistry Journal, 1995The pharmacological properties of a number of novel glycopeptides of glycyrrhizic acid containing fragments of methyl esters of L-amino acids and dipeptides were studied. The compounds were found to have a low toxicity with anti-inflammatory activity combined with an anti-ulcer effect.
S. A. Ryzhova +4 more
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