The Journal of Dermatology, Volume 52, Issue 12, Page 1775-1787, December 2025.ABSTRACT Chronic spontaneous urticaria (CSU) affects 0.5%–1.0% of the population worldwide. However, information on the prevalence, comorbidities, and treatment patterns of CSU in Japan is limited. This observational study consisted of a cross‐sectional and longitudinal part.
Atsushi Fukunaga +3 more
wiley +1 more source
Saudi Pharmaceutical JournalErectile dysfunction (ED) is a growing health condition that needs safe and effective therapy. One of the main common treatments is sildenafil which is used in clinics for managing erectile dysfunction by enhancing the blood supply to the penis.
Ali A. Alamer +8 more
doaj +1 more source
A cellulose synthase-derived enzyme catalyses 3-O-glucuronosylation in saponin biosynthesis
Nature Communications, 2020 Saponins such as glycyrrhizin, a natural sweetener found in licorice root, are a class of triterpenoids synthesized that are characterized by a glucoronic acid moiety at the C-3 position.
Soo Yeon Chung +8 more
doaj +1 more source
Utilization of the ability to induce activation of the nuclear factor (erythroid-derived 2)-like factor 2 (Nrf2) to assess potential cancer chemopreventive activity of liquorice samples [PDF]
Introduction – Nuclear factor (erythroid-derived 2)-like factor 2 (Nrf2) is a transcription factor that regulates expression of many detoxification enzymes.
Akamatsu +46 more
core +1 more source
ChemMedChem, Volume 20, Issue 22, November 18, 2025.The indole derivative (FC‐114) and the N‐phenylpyrazole (FC‐122) of glycyrrhetinic acid are both potent inhibitors of the Protein Tyrosine Phosphatase 1B, with IC50 values of 0.48 μM and 1.15 μM, respectively. However, their activity decreases by up to four times when the 18β‐H position is epimerized to 18α‐H or when the carbonyl group at the C11 ...
Ledy De‐la‐Cruz‐Martínez +10 more
wiley +1 more source
The Protective Role of Glycyrrhizin on Ethanol- Damaged B92 Glial Cells in Vitro
Armaghane Danesh Bimonthly Journal, 2019 Background & aim: Glycyrrhizin is one of the most important pharmacological compounds of the Licorice plant which has anti-inflammatory properties.
L Saleh Haggho +2 more
doaj
EST analysis reveals putative genes involved in glycyrrhizin biosynthesis
BMC Genomics, 2010 Background Glycyrrhiza uralensis is one of the most popular medicinal plants in the world and is also widely used in the flavoring of food and tobacco.
Wang Ning +9 more
doaj +1 more source
Anti-cancer and anti-tumor activity of Glycyrrhiza uralensis Fisch [PDF]
, 2016 Glycyrrhiza uralensis Fisch is an herbaceous perennial legume native to southern Europe and parts of Asia, such as India. The aim of this study is to overview its therapeutic effects than its nutritive and industrial effects.
Miraj, S.
core
EFFECT OF GLYCYRRHIZIN ON ESTROGEN ACTION
Endocrinologia Japonica, 1967 It was demonstrated by the present study that glycyrrhizin inhibited the action of estradiol-17β on uterine weight and β-glucuronidase activity in ovariectomized mice and rats in a certain dose ratio. The inhibition was 50% or more when the dose ratio of glycyrrhizin: estradiol-17β was 1000: 1.
A, Kumagai +4 more
openaire +3 more sources
Efficiency and safety of desloratadine in combination with compound glycyrrhizin in the treatment of chronic urticaria: a meta-analysis and systematic review of randomised controlled trials [PDF]
, 2021 Yulong Wen +3 more
openalex +1 more source