Results 81 to 90 of about 1,222 (163)

Bacterial Extracellular Vesicles in Biomedical Research and Clinical Translation

open access: yesMicrobial Biotechnology, Volume 19, Issue 4, April 2026.
Bacterial membrane vesicle biomedical applications. ABSTRACT Bacterial Extracellular Vesicles (bEVs) are lipid (single‐ or double‐bilayer) nanostructures secreted by virtually all bacteria that play fundamental roles in intercellular communication and have emerged as powerful, multifunctional tools in biomedicine. Their intrinsic ability to encapsulate
Alejandro Arce‐Rodríguez   +2 more
wiley   +1 more source

IgG Responses to Porins and Lipopolysaccharide within an Outer Membrane-Based Vaccine against Nontyphoidal Salmonella Develop at Discordant Rates

open access: yesmBio, 2018
Antibodies acquired after vaccination or natural infection with Gram-negative bacteria, such as invasive Salmonella enterica serovar Typhimurium, can protect against disease.
Anna E. Schager   +18 more
doaj   +1 more source

Cancer Hallmarks Expression in Oral Leukoplakia: Systematic Review and Meta‐Analysis

open access: yesOral Diseases, Volume 32, Issue 2, Page 322-337, February 2026.
ABSTRACT Objectives To assess the available evidence on the expression of hallmarks of cancer and oral leukoplakia (OL) malignant transformation probability, with the goal of identifying the earliest oncogenic molecular events participating in oral cancer carcinogenesis.
I. González‐Ruiz   +4 more
wiley   +1 more source

Yield, purity, and recovery rate of GMMA by the high yield production process.

open access: yes, 2012
*Total protein amount calculated as sum of GMMA-associated protein and soluble protein.#Total protein amount measured directly by Bradford assay.S. sonnei ΔtolR ΔgalU was grown in HTMC in a 5 L fermenter to high densities of OD 45 (A), OD 30 (B1) and OD ...
Allan Saul (34133)   +11 more
core   +1 more source

GMMA from genetically-engineered meningococcus as vaccine for Africa [PDF]

open access: yes, 2015
Gram-negative bacteria naturally shed outer membrane vesicles (OMVs). Structural changes in bacterial outer membrane lead to GMMA, Generalized Modules for Membrane Antigens: outer membrane vesicles to use as vaccine. They are safe, cheap to produce, and
Marini, Arianna
core   +4 more sources

Evaluation of Rational Pharmacotheraphy Training Performed in GMMA: Comparison of Pre- and Post-Training

open access: yesGulhane Medical Journal, 2014
Rational use of medicines (pharmacotherapy) is defined by WHO as ‘’ patients receive the appropriate medicine, in proper dose, for an adequate period of time and at the lowest cost to them and their community.’’ For this aim, rational pharmacotherapy training has been given in GATA Military Medicine Faculty since 2004.
Gokhan Ulusoy   +6 more
openaire   +1 more source

Comparison of Colorimetric Assays with Quantitative Amino Acid Analysis for Protein Quantification of Generalized Modules for Membrane Antigens (GMMA) [PDF]

open access: yesMolecular Biotechnology, 2014
Genetically induced outer membrane particles from Gram-negative bacteria, called Generalized Modules for Membrane Antigens (GMMA), are being investigated as vaccines. Rapid methods are required for estimating the protein content for in-process assays during production.
Omar Rossi   +6 more
openaire   +2 more sources

Diagnostic Yield and Clinical Impact of a Small Genetic Panel for Kidney Disease: A Multicenter, Retrospective European Study

open access: yesClinical Genetics, Volume 109, Issue 1, Page 136-140, January 2026.
In a multicenter study of 692 patients with kidney disease, a 44‐gene panel achieved a 36% diagnostic yield. The 36% yield was not significantly lower than with larger panels or whole‐exome sequencing. A post hoc machine‐learning model identified key predictors to stratify patients into four risk bins (11%–74% yield), enabling more cost‐effective ...
Silvia Giovanella   +22 more
wiley   +1 more source

Association of Sex and Selected Sociodemographic Indicators With Central and Peripheral Arterial Stiffness in Adults Without Cardiovascular Disease: The EVA Follow‐Up Study

open access: yesHealth &Social Care in the Community, Volume 2026, Issue 1, 2026.
The prospective association of sex and sociodemographic indicators with central and peripheral arterial stiffness is poorly understood. The objective was to evaluate the association between sex, marital status, educational attainment, and occupational status and central and peripheral arterial stiffness, as well as their 5‐year progression, in adults ...
Javier Alonso-Diaz   +7 more
wiley   +1 more source

Acrylamide Contamination and Health Risk Assessment in Commercially Produced Potato Chips in Bangladesh

open access: yesJournal of Food Processing and Preservation, Volume 2026, Issue 1, 2026.
This study evaluated acrylamide contamination in 120 potato chip samples representing 40 varieties from five districts in Bangladesh, with three independent samples per variety, and assessed associated health risks. Using validated high‐performance liquid chromatography (HPLC), substantial acrylamide levels were detected, with the highest ...
Kiron Sikdar   +6 more
wiley   +1 more source

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