Results 111 to 120 of about 15,103 (215)
European Journal of Neurology, Volume 33, Issue 2, February 2026.Myasthenia gravis in the very old and with debut after age 65 years increases in incidence and prevalence. Early, active symptomatic and immunosuppressive treatment is needed with the aim of obtaining pharmacological remission or minimal manifestations only. Myasthenic crisis with respiratory failure remains a threat.
Nils Erik Gilhus
wiley +1 more source
Journal of Cellular and Molecular Medicine, Volume 30, Issue 4, February 2026.ABSTRACT Glioblastoma (GBM) features profound immunosuppression and metabolic reprogramming that undermine immunotherapy. We sought biomarkers that capture cytotoxic lymphocyte activity and nominate tractable targets. Using TCGA, we quantified NK/CD8+ T‐cell infiltration (CIBERSORTx), identified differentially expressed genes and derived a three‐gene ...
Shaojie Yu +8 more
wiley +1 more source
Epigenetic reprogramming in multiple myeloma—Challenges and opportunities
International Journal of Cancer, Volume 158, Issue 2, Page 423-432, 15 January 2026.Abstract In cancer, mutational processes act in concert with epigenetic reprogramming to endow malignant cells with hallmark properties that underpin tumorigenesis. Compared with the relatively rigid and slow processes of genetic evolution, the plastic nature of chromatin enables cells to adapt to a changing environment more rapidly.
Subhasree Kumar +2 more
wiley +1 more source
Integrating and Ranking Uncertain Scientific Data [PDF]
, 2008 Mediator-based data integration systems resolve exploratory queries by joining data elements across sources. In the presence of uncertainties, such multiple expansions can quickly lead to spurious connections and incorrect results.
Detwiler, Landon T +4 more
core +6 more sources
Comparison of House Spraying and Insecticide-Treated Nets for Malaria Control. [PDF]
The efficacies of using residual house spraying and insecticide-treated nets against malaria vectors are compared, using data from six recent comparisons in Africa, Asia and Melanesia.
Curtis, Christopher F. +1 more
core
Cellular processes associated with LRRK2 function and dysfunction. [PDF]
, 2015 Mutations in the leucine-rich repeat kinase 2 (LRRK2) encoding gene are the most common cause of monogenic Parkinson's Disease (PD). The identification of LRRK2 polymorphisms associated with increased risk for sporadic PD, as well as the observation that
Bandopadhyay, R, Manzoni, C, Wallings, R
core +1 more source
Differential Elimination and Biological Modelling [PDF]
, 2006 International audienceThis paper describes applications of a computer algebra method, differential elimination, to applied mathematics problems mostly borrowed from biology. The two considered applications are related to the parameters estimation and the
Boulier, François
core +3 more sources
MoleculesGNE myopathy, also known as hereditary inclusion body myopathy (HIBM), is a rare genetic muscle disorder marked by a gradual onset of muscle weakness in young adults.
Cristina Manis +9 more
doaj +1 more source
Lec3 Chinese Hamster Ovary Mutants Lack UDP-N-acetylglucosamine 2-Epimerase Activity Because of Mutations in the Epimerase Domain of the Gne Gene [PDF]
, 2003 Yeongjin Hong, Pamela Stanley
openalex +1 more source
847. Safety and Toxicity Profile of Intra-Muscular and Systemic Delivery of a Novel GNE DNA Liposomal Nanoparticle (GDLP) for Gene Therapy of Hereditary Inclusion Body Myopathy (HIBM2) [PDF]
, 2008 openalex +1 more source