Results 221 to 230 of about 210,635 (269)
Some of the next articles are maybe not open access.
Drugs, 1988
Gonadotrophin-releasing hormone (GnRH) analogues offer a novel approach for the non-steroidal manipulation of the reproductive endocrine axis. GnRH agonists are now effectively employed in the management of precocious puberty, prostate and breast cancer, endometriosis, uterine leiomyoma, polycystic ovarian disease, and various other disorders ...
M, Filicori, C, Flamigni
openaire +2 more sources
Gonadotrophin-releasing hormone (GnRH) analogues offer a novel approach for the non-steroidal manipulation of the reproductive endocrine axis. GnRH agonists are now effectively employed in the management of precocious puberty, prostate and breast cancer, endometriosis, uterine leiomyoma, polycystic ovarian disease, and various other disorders ...
M, Filicori, C, Flamigni
openaire +2 more sources
GnRH analogues—agonists and antagonists
Animal Reproduction Science, 2005GnRH analogues have achieved widespread clinical use for the control of reproduction in animals. Over 2000 analogues of GnRH have been developed and tested over the last 30 years. Paradoxical anti-fertility effects are seen when the more potent agonists are delivered continuously to animals.
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Contraception, 1992
A brief review of 2 lines of research and development of potent analogs of gonadotropin releasing hormone (GnRH) cyclic analogs and linear analogs intended to be safe long acting and hydrophilic is provided. Cyclic analogs of the linear peptide are highly conformationally constrained and hopefully resistant to enzymatic destruction therefore ...
JP Rivier +10 more
openaire +1 more source
A brief review of 2 lines of research and development of potent analogs of gonadotropin releasing hormone (GnRH) cyclic analogs and linear analogs intended to be safe long acting and hydrophilic is provided. Cyclic analogs of the linear peptide are highly conformationally constrained and hopefully resistant to enzymatic destruction therefore ...
JP Rivier +10 more
openaire +1 more source
2020
The field of human reproduction has seen major improvements in the last few decades. As ovarian stimulation plays an integral part for the treatment of infertility, new protocols using an array of different medications and diverse approaches have appeared.
Francisco Javier Ruiz Flores +1 more
openaire +1 more source
The field of human reproduction has seen major improvements in the last few decades. As ovarian stimulation plays an integral part for the treatment of infertility, new protocols using an array of different medications and diverse approaches have appeared.
Francisco Javier Ruiz Flores +1 more
openaire +1 more source
Journal de gynecologie, obstetrique et biologie de la reproduction, 2002
New GnRH antagonists are available in clinical practice. The different studies have confirmed the efficacy of these antagonists in preventing the LH surge. Two protocols have been described: in the multiple dose regimens, small doses of antagonist (0.25 mg) are injected starting on stimulation day 5 or 6 until hCG.
F, Olivennes +5 more
openaire +1 more source
New GnRH antagonists are available in clinical practice. The different studies have confirmed the efficacy of these antagonists in preventing the LH surge. Two protocols have been described: in the multiple dose regimens, small doses of antagonist (0.25 mg) are injected starting on stimulation day 5 or 6 until hCG.
F, Olivennes +5 more
openaire +1 more source
1992
GnRH is a decapeptide, secreted from the hypothalamus in a pulsatile fashion, that regulates the synthesis and secretion of pituitary gonadotropins (1–9). In contrast, synthetic GnRH agonists or antagonists inhibit gonadotropin secretion and subsequently gonadal function (10, 11).
openaire +1 more source
GnRH is a decapeptide, secreted from the hypothalamus in a pulsatile fashion, that regulates the synthesis and secretion of pituitary gonadotropins (1–9). In contrast, synthetic GnRH agonists or antagonists inhibit gonadotropin secretion and subsequently gonadal function (10, 11).
openaire +1 more source