Results 101 to 110 of about 7,213,451 (363)

Goal-Directed Treatment for Osteoporosis: A Progress Report from the ASBMR-NOF Working Group on Goal-Directed Treatment for Osteoporosis. [PDF]

open access: yes, 2017
The American Society for Bone and Mineral Research and the United States National Osteoporosis Foundation (NOF) formed a working group to develop principles of goal-directed treatment and identify gaps that need to be filled to implement this approach ...
Adler   +51 more
core   +1 more source

Force dysmetria in spinocerebellar ataxia 6 correlates with functional capacity

open access: yesFrontiers in Human Neuroscience, 2015
Spinocerebellar ataxia type 6 (SCA6) is a genetic disease that causes pure cerebellar degeneration affecting walking, balance, and coordination. One of the main symptoms of SCA6 is dysmetria.
Agostina eCasamento Moran   +6 more
doaj   +1 more source

Examining Opportunities for Goal-Directed Self-Tracking to Support Chronic Condition Management

open access: yesProceedings of the ACM on Interactive Mobile Wearable and Ubiquitous Technologies, 2019
Although self-tracking offers potential for a more complete, accurate, and longer-term understanding of personal health, many people struggle with or fail to achieve their goals for health-related self-tracking.
J. Schroeder   +4 more
semanticscholar   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

open access: yesMolecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park   +6 more
wiley   +1 more source

Impaired goal-directed behavioural control in human impulsivity. [PDF]

open access: yes, 2017
PublishedJournal ArticleResearch Support, Non-U.S. Gov'tThis is the final version of the article. Available from Taylor & Francis (Routledge) via the DOI in this record.Two dissociable learning processes underlie instrumental behaviour.
Baess, K, Chase, HW, Hogarth, L
core   +1 more source

Early Goal Directed Therapy: Do We Reach the End of Road?

open access: yesArchives of Anesthesia and Critical Care, 2016
No ...
Ata Mahmoodpoor, Samad EJ Golzari
doaj  

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte   +10 more
wiley   +1 more source

Influence on Habitual versus Goal-Directed Decision Making [PDF]

open access: yes, 2016
Different systems for habitual versus goal-directed control are thought to underlie human decision-making. Working memory is known to shape these decision-making systems and their interplay, and is known to support goal- directed decision making even ...
Heinz, Andreas   +4 more
core   +1 more source

Effortful goal-directed behavior in schizophrenia: Computational subtypes and associations with cognition.

open access: yesJournal of Abnormal Psychology, 2019
Schizophrenia is associated with amotivation and reduced goal-directed behavior, which have been linked to poor functional outcomes. Motivational deficits in schizophrenia are often measured using effort-based decision-making (EBDM) paradigms, revealing ...
J. Cooper   +5 more
semanticscholar   +1 more source

An approach for coherent periodogram averaging of tilt‐series data for improved contrast transfer function estimation

open access: yesFEBS Open Bio, EarlyView.
The contrast transfer function (CTF) is an imaging aberration that is a major resolution‐limiting factor in cryo‐electron microscopy (cryo‐EM). Precise CTF estimation is key to overcoming this limitation, but is particularly challenging in cryo‐electron tomography (cryo‐ET) data. Here, we present an approach for using geometric information to assist in
Sagar Khavnekar, William Wan
wiley   +1 more source

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