Results 111 to 120 of about 7,767,661 (277)
Revista Brasileira de AnestesiologiaBackground: The goal directed hemodynamic therapy is an approach focused on the use of cardiac output and related parameters as end-points for fluids and drugs to optimize tissue perfusion and oxygen delivery.
Javier Ripollés +7 more
doaj +1 more source
Individualized Goal-Directed Therapy: The Challenge With the Fluids
Anesthesia & Analgesia, 2020 Tim G, Kampmeier, Christian, Ertmer
openaire +3 more sources
Effect of a Machine Learning Algorithm to Guide Goal-Directed Therapy After Cardiac Surgery
Background Goal-directed therapy allows clinicians to optimize perfusion and volume status in patients postoperatively.
Alexandra Deasel +3 more
core +1 more source
Advanced Science, EarlyView.Guided by spatial transcriptomics and clinical validation, a threaded microneedle platform enables precise layer‐specific delivery across the dermis and subcutaneous tissue. By addressing distinct pathogenic remodeling in different skin layers, this strategy coordinates compartment‐specific intervention, restores tissue architecture, and offers a ...
Fangzhou Xie +14 more
wiley +1 more source
Journal of Gastrointestinal SurgeryPancreaticoduodenectomy (PD) is the only curative option for localized pancreatic head and periampullary malignancies. However, PD is associated with significant perioperative morbidity. Perioperative fluid management has emerged as an important modifiable factor influencing surgical outcomes in PD.In this qualitative review, PubMed/Medline searches ...
Meghan Grim +5 more
openaire +2 more sources
Advanced Science, EarlyView.Immune checkpoint inhibition (ICI) reshapes the hippocampal neuroimmune niche. Spatial transcriptomic profiling and human brain histological analyses identify neuroinflammation and altered neuronal and glial programs. Notably, T cell depletion prevents ICI‐driven microglial activation, establishing the T cell–microglia crosstalk axis as a driving ...
Devyani Swami +7 more
wiley +1 more source
The History of Goal-Directed Therapy and Relevance to Cardiopulmonary Bypass
, 2015 Goal-directed therapy is a patient care strategy that has been implemented to improve patient outcomes. The strategy includes aggressive patient management and monitoring during a period of critical care.
Joseph J. Sistino +3 more
core +1 more source
Smart Bioinks for 4D Bioprinting: Requirements, Design, and Applications
Advanced Science, EarlyView.Smart bioinks empower 4D‐bioprinted constructs to dynamically adapt and remodel in response to stimuli, effectively biomimicking native tissues. Artificial Intelligence (AI) and Machine Learning (ML) play a guiding role in their rational design by optimizing relevant properties.
Shangsi Chen +11 more
wiley +1 more source
Effect of goal-directed haemodynamic therapy in free flap reconstruction for head and neck cancer
, 2018 BACKGROUND: In free flap reconstruction for head and neck cancer, achieving a haemodynamic target using excessive fluid infusion is associated with decreased flap survival rates and extended hospital stays. We hypothesized that goal-directed haemodynamic
김현주 +4 more
core +1 more source
Advanced Science, EarlyView.Alternate‐day fasting suppresses mitochondrial complex II assembly via SDHAF4 to upregulate hepatocyte eNOS. The resulting nitric oxide S‐nitrosylates ATG7 at C184 in hepatic stellate cells, restraining autophagic flux and preventing their profibrotic activation.
Xueqiang Wang +17 more
wiley +1 more source