X‐shaped DNA promotes multivalent cGAS assembly and enhances cGAS‐STING signaling. When conjugated with antigenic peptides, the resulting X‐DNA‐based peptide vaccine promotes dendritic cell activation, antigen presentation, and antitumor T‐cell responses.
Jiabei Li +7 more
wiley +1 more source
Restricted Versus Liberal Versus Goal-Directed Fluid Therapy for Non-vascular Abdominal Surgery: A Network Meta-Analysis and Systematic Review. [PDF]
Yang TX +4 more
europepmc +1 more source
Composite‐based flexible electronics integrate biodegradable polymers, conductive networks, and multilayer device architectures to balance electrical performance, mechanical durability, and controlled degradation. Interfacial engineering and encapsulation regulate transport stability and operational lifetime, while programmed disassembly enables ...
Sayam, Sangho Cho
wiley +1 more source
Comment on: "A comparative study of stroke volume variation and plethysmography variability index as goal-directed fluid therapy in major abdominal oncosurgeries". [PDF]
Narayanan V.
europepmc +1 more source
Dobutamine and Goal-Directed Fluid Therapy for Improving Tissue Oxygenation in Deep Inferior Epigastric Perforator (DIEP) Flap Breast Reconstruction Surgery: Protocol for a Randomized Controlled Trial. [PDF]
Mizubuti GB +12 more
europepmc +1 more source
MicroRNA‐941 Acts as a Novel Prognostic Predictor and Oncogenic Driver in Colorectal Cancer
Upregulation of miR‐941 was a promising diagnostic and prognostic biomarker for CRC patients. Inhibition of miR‐941 significantly suppressed CRC cellular events and triggered ferroptosis. The oncogenic functions of miR‐941 were mediated through targeting TRPS1.
Hong Li +5 more
wiley +1 more source
Gastric cancer metastasis should be considered according to its anatomical route, because lymphatic, peritoneal, and hematogenous dissemination involve partly distinct molecular mechanisms. This review summarizes metastasis pattern‐associated and pattern‐specific molecules identified using surgical specimens, evaluates their evidence and translational ...
Mitsuro Kanda
wiley +1 more source
Comparison of Goal-Directed Fluid Therapy and Conventional Fluid Therapy in Elective Major Abdominal Surgery: A Meta-Analysis of Randomized Controlled Trials. [PDF]
Ashraf N, Zargar OUU, Albina A.
europepmc +1 more source
A Pilot Study Assessing a Closed-Loop System for Goal-Directed Fluid Therapy in Abdominal Surgery Patients. [PDF]
Gricourt Y +10 more
europepmc +1 more source
Cell Segmentation Beyond 2D—A Review of the State‐of‐the‐Art
Cell segmentation underpins many biological image analysis tasks, yet most deep learning methods remain limited to 2D despite the inherently 3D nature of cellular processes. This review surveys segmentation approaches beyond 2D, comparing 2.5D and fully 3D methods, analyzing 31 models and 32 volumetric datasets, and introducing a unified reference ...
Fabian Schmeisser +6 more
wiley +1 more source

