Results 201 to 210 of about 6,816,256 (279)

Astrocyte SMN Restoration and Forskolin Treatment Improve SMA Synaptic Pathology

open access: yesAnnals of Neurology, EarlyView.
Objective Early phenotypic presentation of central afferent synapse dysfunction within patients with spinal muscular atrophy (SMA) represents a key target for therapeutic development; however, the underlying disease mechanisms remain unresolved. By further investigating motor neuron synapse and peri‐synaptic astrocyte process (PAP) defects in human SMA
Emily Welby   +6 more
wiley   +1 more source

Translational Macrophage Mechano‐Immunotherapy for Next‐Generation Implantable Biomaterials

open access: yesAdvanced NanoBiomed Research, EarlyView.
This review explores how macrophage mechanosensing drives inflammation, fibrosis and foreign body responses to implanted biomaterials. It examines emerging pharmacological strategies to modulate mechanotransduction, alongside biomaterial platforms for localised drug delivery, clinical translation, regulatory considerations and standardised testing ...
Xueying Xu, Ian L. Chin, Richard P. Tan
wiley   +1 more source

Scoping literature review: Comparing MRI tractography methods for optic radiation analysis

open access: yesThe Anatomical Record, EarlyView.
Abstract Accurate tractography mapping of the optic radiations is essential to avoiding post‐operative visual field deficits in patients undergoing temporal lobe surgery. This literature review highlights the current landscape of MRI tractography methods that are used to delineate the optic radiations (ORs), with a particular focus on the anterior ...
Hriday Sahni   +3 more
wiley   +1 more source

Feasibility of Goal-Directed Fluid Therapy in Patients with Transcatheter Aortic Valve Replacement - An Ambispective Analysis. [PDF]

open access: yesBraz J Cardiovasc Surg
Trauzeddel RF   +7 more
europepmc   +1 more source

Magnetic Resonance Imaging Findings and Demographics Predict Surgical Versus Nonoperative Management of Rotator Cuff Injuries: A Natural Language Processing Analysis

open access: yesArthroscopy, EarlyView.
Purpose To identify pathologic and demographic predictors of treatment selection and timing in patients with rotator cuff injuries using natural language processing of magnetic resonance imaging (MRI) reports. Methods Data were retrospectively reviewed in our institution's Information Commons database.
Timothy S. Keeley   +7 more
wiley   +1 more source

Goal-Directed Fluid Therapy Using Pulse Pressure Variation in Thoracic Surgery Requiring One-Lung Ventilation: A Randomized Controlled Trial. [PDF]

open access: yesJ Clin Med
Punzo G   +12 more
europepmc   +1 more source

Gut Health in Ostriches (Struthio camelus): Insights Into Intestinal Structure, Functions, Microbiome, and Improvement Strategies

open access: yesAnimal Research and One Health, EarlyView.
Our paper systematically reviews the intestinal structure, function, and microbiota of ostriches, along with strategies for improving their gut health. We analyze how these factors collectively influence intestinal homeostasis and ostrich welfare, emphasizing probiotics as a promising intervention to enhance gut health, boost population well‐being, and
Zi‐Qun Zhang   +6 more
wiley   +1 more source

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