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OPTIMASI PRODUKSI COCO FIBER DARI LIMBAH KELAPA MENGGUNAKAN METODE PREEMPTIVE GOAL PROGRAMMING

Jurnal Lebesgue, 2023
Penelitian ini membahas tentang optimasi produksi Coco Fiber dari limbah kelapa menggunakan metode Preemptive Goal Programming dengan tujuan yang ingin dicapai yaitu, memaksimalkan banyaknya produksi, meminimalkan biaya produksi, memaksimalkan keuntungan
Zepri Johanda, Hendra Cipta, Muhammad Fathoni   +2 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

What Does Aspect-Oriented Programming Mean for Functional Programmers? [PDF]

, 2009
Aspect-Oriented Programming (AOP) aims at modularising crosscutting concerns that show up in software. The success of AOP has been almost viral and nearly all areas in Software Engineering and Programming Languages have become "infected" by the AOP bug ...
Oliveira, Bruno, Wang, Meng
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

A Visual Programming Paradigm for Abstract Deep Learning Model Development

, 2019
Deep learning is one of the fastest growing technologies in computer science with a plethora of applications. But this unprecedented growth has so far been limited to the consumption of deep learning experts.
Aralikatte, Rahul, Khare, Shreya, Mani, Senthil, Panwar, Naveen, Sankaran, Anush, Tamilselvam, Srikanth   +5 more
core   +1 more source

Goal programming approach to fully fuzzy fractional transportation problem

Journal of Taibah University for Science, 2019
In this paper, authors devoted to study a fully fuzzy fractional multi-objective transportation problem by using goal programming approach. Also trapezoidal membership functions are applied to each objective function and constraints to describe a each ...
P. Anukokila, B. Radhakrishnan
doaj   +1 more source

Surgical Operation Scheduling with Goal Programming and Constraint Programming: A Case Study

Mathematics, 2019
The achievement of health organizations’ goals is critically important for profitability. For this purpose, their resources, materials, and equipment should be efficiently used in the services they provide.
Şeyda Gür, Tamer Eren, Hacı Mehmet Alakaş   +2 more
doaj   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source