Results 71 to 80 of about 1,001,655 (296)

A Fuzzy Goal Programming Model for Efficient Portfolio Selection. [PDF]

open access: yesJournal of Optimization in Industrial Engineering, 2017
This paper considers a multi-objective portfolio selection problem imposed by gaining of portfolio, divided yield and risk control in an ambiguous investment environment, in which the return and risk are characterized by probabilistic numbers.
Abolfazl Kazemi   +2 more
doaj   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

open access: yesAging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef   +2 more
wiley   +1 more source

Aplicação de Goal programming em um problema florestal [PDF]

open access: yesCiência Florestal, 2002
The objective of this paper is to apply one of the techniques of multi -objective programming (goal programming) in a Brazilian forest problem, through of a case study accomplished in the Sant a Câ ndida Farm, in General Carneiro, Paraná, Brazil.
Fabiane de Oliveira   +2 more
doaj   +1 more source

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani   +8 more
wiley   +1 more source

Applying an Ethical Lens to the Treatment of People With Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The practice of neurology requires an understanding of clinical ethics for decision‐making. In multiple sclerosis (MS) care, there are a wide range of ethical considerations that may arise. These involve shared decision‐making around selection of a disease‐modifying therapy (DMT), risks and benefits of well‐studied medications in comparison to
Methma Udawatta, Farrah J. Mateen
wiley   +1 more source

Supported Evacuation for Disaster Relief through Lexicographic Goal Programming

open access: yesMathematics, 2020
Disasters have been striking human-beings from the beginning of history and their management is a global concern of the international community. Minimizing the impact and consequences of these disasters, both natural and human-made, involves many ...
Inmaculada Flores   +3 more
doaj   +1 more source

Diagnostic Utility of the ATG9A Ratio in AP‐4–Associated Hereditary Spastic Paraplegia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Adaptor protein complex 4–associated hereditary spastic paraplegia (AP‐4‐HSP), a childhood‐onset neurogenetic disorder and frequent mimic of cerebral palsy, is caused by biallelic variants in the adaptor protein complex 4 (AP‐4) subunit genes (AP4B1 [for SPG47], AP4M1 [for SPG50], AP4E1 [for SPG51], and AP4S1 [for SPG52]).
Habibah A. P. Agianda   +12 more
wiley   +1 more source

An artificial intelligence approach to goal programming goal structure development using AHP [PDF]

open access: yes, 2000
An expert system is proposed to help non-operation research users to formulate goal programs. The developmental tool being used is VP-Expert. The proposed expert system will used constraint information to assist users in goal selection.
Iyengar, Jagan, Srivatsava, Mukesh
core  

Maximization of Palm Fruit Planted Area Using a Goal Programming Approach

open access: yesJournal of Computing Research and Innovation, 2018
Malaysia has suffered from a low production of palm fruit. This will affect the economy in Malaysia. Malaysia has to solve this problem and must find the effective ways to increase the production of palm fruit.
Wan Nurshazelin Wan Shahidan   +1 more
doaj  

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