Results 21 to 30 of about 307,088 (313)

Agro pastoralists’ awareness and knowledge on contagious caprine Pleuropneumonia in two selected counties in Kenya

open access: yesCogent Food & Agriculture, 2022
Poor identification of Contagious caprine pleuropneumonia diseases from its signs and symptoms is a major problem to goat farmers which leads to use of wrong method of disease control.
Fredrick Ochieng Ouya   +4 more
doaj   +1 more source

Sheep and goat pathogen database: a pathogen data integration and analysis database of sheep and goat infectious diseases

open access: yesFrontiers in Microbiology
The prevalence of infectious diseases in sheep and goats has a significant impact on the development of the sheep and goat industry and public health security.
Haoju Pan   +14 more
doaj   +1 more source

Genome-Wide Population Structure and Selection Signatures of Yunling Goat Based on RAD-seq

open access: yesAnimals, 2022
Animal diseases impose a huge burden on the countries where diseases are endemic. Conventional control strategies of vaccines and veterinary drugs are to control diseases from a pharmaceutical perspective.
Yuming Chen   +5 more
doaj   +1 more source

Comparison of sheep and goat colostrum fatty acids contents [PDF]

open access: yesBIO Web of Conferences
The quality and content of colostrum is a very important factor for the health of the offspring. Colostrum is the first food that ensures the growth and development of offspring and their immunity against diseases.
Anitaş Özgül, Göncü Serap
doaj   +1 more source

Current status, challenges and the way forward for dairy goat production in Asia – conference summary of dairy goats in Asia [PDF]

open access: yesAsian-Australasian Journal of Animal Sciences, 2019
Asia hosts more than half of the world’s 1 billion goats and is also where domestication of wild goats began. Goats, including dairy goats, are adapted to a wide variety of harsh environments and thus play key roles as providers of nutrition, food ...
Juan Boo Liang, Pramote Paengkoum
doaj   +1 more source

Discovery of novel inhibitors of ghrelin O-acyltransferase enzyme: an in-silico approach

open access: yesResearch in Pharmaceutical Sciences, 2022
Background and purpose: Ghrelin is known as a hunger hormone and plays a pivotal role in appetite, food intake, energy balance, glucose metabolism, and insulin secretion, making it a potential target for the treatment of obesity and type 2 diabetes.
Faezeh Sadat Hosseini   +2 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

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