A spiral microfluidic chip is compared with ultrafiltration for the separation of extracellular vesicles (EVs). The method preserves miRNA cargo and membrane integrity more effectively, resulting in intact vesicle morphology and consistent surface biomarker expression.
Huiseop Lee +5 more
wiley +1 more source
An Accessible Microfluidic Platform for the Generation of Polarized Brain Organoids
This study presents an accessible double‐gradient microfluidic device that enables controlled morphogen delivery and spatially polarized differentiation in brain organoids. By integrating a pump‐free design and stable fabrication method, the platform generates dorsal–ventral neuronal asymmetry, offering a reproducible and versatile approach to model ...
Daniel Pérez‐Calixto +6 more
wiley +1 more source
Prevalence and associated risk factors of Trypanosomosis in small ruminants of Abe Dongoro District, Western Ethiopia. [PDF]
Wamile M +4 more
europepmc +1 more source
Topography‐Regulated Screening Platform for Myoblast Contact Guidance
This study develops a topography‐regulated screening platform (12 gradients in 96‐topography‐well plate) enabling analysis of skeletal muscle morphogenesis. The topography‐induced cell morphology changed, cell polarization, and myotube differentiation, establishing an evaluative framework for generating pathologically relevant myotube phenotypes to ...
Tianqi Feng +6 more
wiley +1 more source
Dietary N-acetylcysteine enhances sperm motility by remodeling the rumen microbiome and its metabolic axis in goats. [PDF]
Luo J +11 more
europepmc +1 more source
A Pressure Microsensor Made of Parylene‐C for Use as Medical Implant
A monolithic parylene‐C pressure sensor with gold strain gauges provides 6.2 μV$\mu{\rm V}$·mmHg$\cdot{\rm mmHg}$−1$^{-1}$ sensitivity. The morphology of a sputtered thin film strain sensor is granular/columnar, which results in a high gauge factor of 7.5. Thermal bonding and parylene‐C coating create a hermetic cavity.
Ann‐Kathrin Klein +2 more
wiley +1 more source
Rumen bacteria, carcass traits, and meat quality of growing goat fed diets with different levels of Azolla Pinnata. [PDF]
Rabee AE +5 more
europepmc +1 more source
Additive Manufacturing of Patient‐Specific Intracranial Aneurysm Cell Culture Models
Patient‐specific intracranial aneurysm models were fabricated using chocolate moulding, 3D printed water‐soluble cores, and direct resin 3D printing. Moulding PDMS around sacrificial cores made of chocolate or 3D printed water‐soluble resin yielded accurate, expandable, and endothelializable models that outperformed resin‐based approaches.
Chloe M. de Nys +6 more
wiley +1 more source
Molecular Epidemiology and Genotype Diversity of Severe Fever with Thrombocytopenia Syndrome Virus in Goats in South Korea. [PDF]
Ouh IO.
europepmc +1 more source
We performed a computational screening of phosphorescent emitters and charge transporters for OLEDs to identify combinations that minimize triplet‐polaron quenching, a major cause of efficiency loss and short operational lifetimes, especially in blue OLEDs. Our results reveal key design rules and highlight emitter‐transporter pairs that strongly reduce
Clint van Hoesel +2 more
wiley +1 more source

