Results 161 to 170 of about 56,489 (258)

Human iPSC‐Derived Vascularised Lung Organoids for Modelling COPD and Pulmonary Hypertension

Cell Proliferation, EarlyView.
Vascularised lung organoids (vLOs) that faithfully mimic human lung tissue architecture and disease pathology are critical for advancing pulmonary research but remain challenging to generate. Here, we developed a robust self‐organisation protocol to produce vLOs with cellular heterogeneity and functional vasculature. The engineered blood vessels within
Simin Jiang, Liangliang Tian, Jingge Qu, Yi Hong, Dian Chen, Zihang Pan, Huanyu Long, Lanhe Chu, Weijing Kong, Qiyang Yao, Xiaojing Ma, Yun Zhao, Baihui Ma, Kai Wang, Yahong Chen   +14 more
wiley   +1 more source

Correction: Neonatal microbiota colonization primes maturation of goblet cell-mediated protection in the pre-weaning colon. [PDF]

J Exp Med
Johansson Å, Subramani MV, Yilmaz B, Nyström EEL, Layunta E, Arike L, Sommer F, Rosenstiel P, Vereecke L, Mannerås-Holm L, Wullaert A, Pelaseyed T, Johansson MEV, Birchenough GMH.   +13 more
europepmc   +1 more source

Mechanisms underpinning the progression of nondysplastic Barrett's oesophagus to cancer

The FEBS Journal, EarlyView.
Barrett's oesophagus confers a low but significant cancer risk. The condition is common but we do not have effective biomarkers to identify susceptible patients. We believe that there is no single factor that determines cancer risk and an understanding of the combinations of interactions (via gene expression and natural selection) between the Barrett's
Yannick H. Derwa, Meng‐Lay Lin, Stuart A. C. McDonald   +2 more
wiley   +1 more source

When Appendicitis Masks a Malignancy: A Case of Appendiceal Goblet Cell Adenocarcinoma. [PDF]

Cureus
Gardner BM, Haymov A, Jones R.
europepmc   +1 more source

Traditional serrated adenoma of the colorectum: Evolving concepts in histological classification and terminology

Histopathology, EarlyView.
The definition of the colorectal traditional serrated adenoma (TSA) has evolved to recognize a broader morphological spectrum, including classical, flat and mixed lesions reflecting early development and neoplastic progression. Updated WHO classification highlights the need for consistent terminology to improve recognition and to distinguish TSA from ...
Christophe Rosty, Maurice B. Loughrey, Taiki Hashimoto, Markus Mäkinen, Rish K. Pai, Shigeki Sekine, Rhonda K. Yantiss, Iris D. Nagtegaal   +7 more
wiley   +1 more source

Three in one: a case report of mixed neuroendocrine tumor, goblet cell adenocarcinoma and low-grade mucinous neoplasm in a single appendix. [PDF]

J Surg Case Rep
Lin V, Rutland T, Gibson K, Farzin M.
europepmc   +1 more source

Local Delivery of a Bio‐Engineered IL‐37 Fc‐Fusion Ameliorates Experimental Allergic Asthma in Mice

Allergy, EarlyView.
Lars P. Lunding, Marcel F. Nold, Claudia A. Nold‐Petry, Michael Wegmann   +3 more
wiley   +1 more source

Comprehensive and reproducible grading of the Updated Sydney System in gastric biopsies using artificial intelligence: multi‐pathologist validation and a reader study

Histopathology, EarlyView.
SydneyMTL is an interpretable multi‐task model providing four‐level grading for the five Sydney System attributes. By significantly improving diagnostic concordance and reducing reading time, it offers a robust clinical tool to alleviate pathologist workloads and standardize routine gastric biopsy screening.
Ho Heon Kim, Won Chan Jeong, Yuri Hwang, Gisu Hwang, Kyungeun Kim, Young Sin Ko   +5 more
wiley   +1 more source

Cetobacterium somerae ZNN-1 promotes goblet cell differentiation through glutamine-mediated Notch signaling suppression. [PDF]

J Adv Res
Zhou NN, Liu JX, Wang T, Wang Z, Li LK, Qiao F, Du ZY, Zhang ML.   +7 more
europepmc   +1 more source

Comparison of intestinal histopathological changes following teclistamab, BCMA‐directed CAR T, CD19‐directed CAR T and rituximab therapies

Histopathology, EarlyView.
This is a retrospective review of intestinal tract biopsies from patients treated with various cellular immunotherapies (BCMA and CD19‐directed CAR T, teclistamab and rituximab therapies). We found distinct but overlapping histologic patterns across treatment groups, with lamina propria plasma cell depletion, crypt apoptotic bodies and active ...
Olivia J Leung, Esther Baranov, Isairis Peralta Valerio, Robin Collingwood, Natalie Respond, Don Siegel, Pooja Devi, Kristen M. Stashek   +7 more
wiley   +1 more source