Results 61 to 70 of about 3,575 (179)

Safety and Feasibility of Pulsed Electric Field Ablation for Early‐Stage Non‐Small Cell Lung Cancer Prior to Surgical Resection

Journal of Surgical Oncology, Volume 131, Issue 8, Page 1529-1542, June 2025.
ABSTRACT Background and Methods Surgery remains the standard of care for non‐small cell lung cancer (NSCLC) but is applicable to ≤ 30% of patients. Pulsed Electric Fields (PEF) ablation uses short‐duration, high‐voltage electrical pulses to induce cell death without relying on thermal mechanisms.
Marcelo Jimenez, Javier Flandes, Erik H. F. M. van der Heijden, Calvin S. H. Ng, Jeffrey S. Iding, José F. Garcia‐Hierro, Borja Recalde‐Zamacona, Roel L. J. Verhoeven, Rainbow W. H. Lau, Alicia Moreno‐Gonzalez, Beryl A. Hatton, Partha Seshaiah, Maria B. Plentl, William S. Krimsky   +13 more
wiley   +1 more source

Surgical Treatment of Appendiceal Adenocarcinoid (Goblet Cell Carcinoid) [PDF]

, 2018
Adenocarcinoid of the appendix is an infrequent tumor with histologic features of both adenocarcinoma and carcinoid tumor. Although its malignant potential remains unclear, adenocarcinoids seem to be biologically more aggressive than conventional ...
Bucher, Pascal, Egger, Jean-François, Gervaz, Pascal, Morel, Philippe, Oulhaci, Wassila, Ris, Frederic   +5 more
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Immunohistochemical markers of cancerogenesis in the lung. [PDF]

, 2007
Lung cancer is the leading cause of cancer deaths for people of both sexes worldwide. Early diagnosis of precancer lesions may be of crucial significance to lowering lung cancer mortality.
Jacek Nikliński, Lech Chyczewski, Lukasz Minarowski, Walentyn Pankiewicz, Wiesława Niklińska, Wojciech Naumnik   +5 more
core   +2 more sources

Therapeutic targeting of TGF‐β in lung cancer

The FEBS Journal, Volume 292, Issue 7, Page 1520-1557, April 2025.
Here, we discuss how lung cancer treatment can be transformed by targeting TGF‐β for better outcomes. Inhibiting TGF‐β signaling halts tumor growth, boosts immune response, and enhances treatment efficacy. By tackling TGF‐β's role in epithelial–mesenchymal transition (EMT) and immune evasion, this approach opens new avenues for more effective lung ...
Sajjad Aftabi, Amir Barzegar Behrooz, Marco Cordani, Niloufar Rahiman, Mohammadamin Sadeghdoust, Farnaz Aligolighasemabadi, Stephen Pistorius, Seyedeh Hoda Alavizadeh, Nima Taefehshokr, Saeid Ghavami   +9 more
wiley   +1 more source

Perspectives on testicular sex cord-stromal tumors and those composed of both germ cells and sex cord-stromal derivatives with a comparison to corresponding ovarian neoplasms [PDF]

, 2017
Sex cord-stromal tumors (SCSTs) are the second most frequent category of testicular neoplasms, accounting for approximately 2–5% of cases. Both genetic and epigenetic factors account for the differences in frequency and histologic composition between ...
Cheng, Liang, Lyu, Bingjian, Roth, Lawrence M.   +2 more
core   +1 more source

E‐selectin affinity glycoproteomics reveals neuroendocrine proteins and the secretin receptor as a poor‐prognosis signature in colorectal cancer

Molecular Oncology, Volume 19, Issue 3, Page 635-658, March 2025.
Screening colorectal tumors for glycoproteins linked to disease progression has revealed several potential therapeutic targets. The secretin receptor (SCTR), identified as a marker of poor prognosis and metastasis in colorectal cancer, has been shown to be a key carrier of N‐glycans with sialylated Lewis antigens. These cancer‐specific glycoproteoforms
Sofia Cotton, Dylan Ferreira, Marta Relvas‐Santos, Andreia Brandão, Luís Pedro Afonso, Andreia Miranda, Eduardo Ferreira, Beatriz Santos, Martina Gonçalves, Paula Lopes, Lúcio Lara Santos, André M. N. Silva, José Alexandre Ferreira   +12 more
wiley   +1 more source

Goblet cell carcinoid of the appendix: a case report [PDF]

Turkish Journal of Pathology, 2014
Goblet cell carcinoid of the appendix is a rare neuoroendocrine tumor that possesses histological features of both adenocarcinoma and neuoroendocrine tumor. Goblet cell carcinoid of the appendix is more aggressive than conventional neuroendocrine tumors. Here we report a case of a 54-year-old woman with goblet cell carcinoid tumor in the appendix.
Dudu Solakoğlu, Kahraman, Niyazi, Akin
openaire   +2 more sources

UEG Week 2023 Poster Presentations

, 2023
United European Gastroenterology Journal, Volume 11, Issue S8, Page 535-1498, October 2023.
wiley   +1 more source

Integrated omics revealed the altered colonic microenvironment after inhibition of peripheral serotonin synthesis by LP533401

iMetaOmics, Volume 1, Issue 2, December 2024.
The colonic microenvironment of neonatal rats was altered after administration of the peripheral 5‐hydroxytryptamine (5‐HT) inhibitor LP533401, resulting in increased crypt depth and decreased myenteric thickness. Multi‐omics approaches, including metagenomics, transcriptomics, and metabolomics, in combination with immunofluorescence, were employed to ...
Yidan Ling, Ziyu Liu, Shuibing Han, Haiqin Wu, Chunlong Mu, Weiyun Zhu   +5 more
wiley   +1 more source

The pathologists’ eyes on foregut: histopathological relations in the experimental and routine diagnostics [PDF]

, 2011
SUMMARY I. The study aimed to investigate the incidence of duodeno-gastroesophageal reflux-induced malignoma formation in a series of duodeno-esophageal anastomosis operations in rats.
Németh István Balázs
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