BACKGROUND & AIMS: Stem cells within the intestinal epithelium generate daughter cells that undergo lineage commitment and maturation through the combined action of the Wnt and Notch signaling cascades.
Clevers, H. +15 more
core +1 more source
Club and goblet secretory cells are both present in the epithelial space of the BEM.
a) Immunofluorescence staining of ClCs (positive for CCSP, red). b) Immunofluorescence staining of ClCs (positive for CCSP, red) and goblet cells (positive for MUC5AC, green). c) Immunofluorescence staining reveals the presence of cells positive for both
Silvia Maccari (2621929) +6 more
core +1 more source
Deep crypt secretory cells shape region-specific mucin glycosylation patterns in the mouse colon.
The colonic mucin layer, comprising highly glycosylated mucin proteins, is crucial for maintaining colonic health. Its region-specific glycosylation patterns are indispensable for adapting to distinct physiological and microbial environments along the ...
Daisuke Sugahara +2 more
doaj +1 more source
Functional analysis of TL1A/DR3 interactions during T cell-mediated immune responses
Members of the tumour necrosis factor superfamily (TNFSF) are important regulators of inflammation and immunity. TL1A (TNFSF15), ligand for death receptor 3 (DR3), is the most recently discovered member of this superfamily and full understanding of its ...
Ślebioda, Tomasz Jerzy
core +1 more source
Porcine intestinal goblet cells: Guardians of mucosal immunity and barrier function. [PDF]
Cui C +8 more
europepmc +1 more source
Localization of a new serine protease, ingobsin, in goblet cells in rat, pig and man
A serine protease, ingobsin, that cleaves Lys-x and Arg-x, has been purified from rat duodenal tissue. By immunohistochemical methods, the enzyme was localized in goblet cells in the small intestine of rat, pig, and man.
Poulsen, Steen Seier, Nexø, Ebba
core
Human amniotic epithelial cell-derived exosomes promote conjunctival goblet cells proliferation and mucin secretion. [PDF]
Meng T, Yang S, Wu W, Gong M, Zhang Y.
europepmc +1 more source
Geometrically Constrained Growth Factor Concentration Favors Enrichment of Goblet Cells and Mucus Formation. [PDF]
Villegas-Novoa C +5 more
europepmc +1 more source
Spatial transcriptomics reveals compartment-specific cytotoxic T cell crosstalk with AT2 and goblet cells in advanced COPD. [PDF]
Syarif AH +13 more
europepmc +1 more source

