Results 191 to 200 of about 4,484,465 (292)

Monitoring Mitochondrial Function With High‐Resolution Respirometry During Ex‐Situ Heart Perfusion

open access: yesArtificial Organs, EarlyView.
Normothermic ESHP preserves mitochondrial respiratory function over 6 h in a porcine model (n = 6): OXPHOS capacities across NADH‐, fatty‐acid‐, and succinate‐linked pathways remain stable, with reduced cytochrome‐c control efficiency indicating improved outer‐membrane integrity. HRR provides a rapid, actionable readout for organ assessment.
Lukas Stastny   +12 more
wiley   +1 more source

Pyrimidinergic P2Y1-Like Nucleotide Receptors Are Functional in Rat Conjunctival Goblet Cells. [PDF]

open access: yesInvest Ophthalmol Vis Sci
Fjærvoll KA   +5 more
europepmc   +1 more source

Aqueous chlorhexidine versus povidone‐iodine for ocular antisepsis: A systematic review and meta‐analysis

open access: yesActa Ophthalmologica, EarlyView.
Abstract This systematic review and meta‐analysis aimed to compare aqueous chlorhexidine (AqCHX) with povidone‐iodine (PI) for ocular antisepsis in preventing post‐procedural endophthalmitis (primary outcome) and to evaluate antimicrobial efficacy and patient‐reported pain (secondary outcomes).
Hande Coskun   +5 more
wiley   +1 more source

Nematode in Cockroaches: A Potential Allergen Source

open access: yes
Allergy, EarlyView.
Dongjun Kang   +5 more
wiley   +1 more source

Long non‐coding RNAs at the crossroads of inflammation, cancer and angiogenesis: Molecular mechanisms and their potential as therapeutic targets

open access: yesBritish Journal of Pharmacology, EarlyView.
Long non‐coding RNAs (lncRNAs), a broad class of non‐protein‐coding RNAs, are characterized as new regulators of gene expression at the epigenetic, transcriptional, and post‐transcriptional level. Thus, lncRNAs are involved in the regulation of physiological processes and the development of human diseases and cancer by modulating proinflammatory ...
Charlie Leboff   +3 more
wiley   +1 more source

Alamandine/MrgD pathway modulates gut–bone marrow axis in ageing

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Ageing is associated with colon epithelial barrier disruption and up‐regulation of myelopoiesis in the bone marrow (BM). Alamandine (Ala) and MrgD are novel members of the renin angiotensin system (RAS). This study tested the hypothesis that Ala restores the colon epithelial barrier integrity in ageing via modulating gut–
Kishore Chittimalli   +6 more
wiley   +1 more source

Colonic epithelial-derived FGF1 drives intestinal stem cell commitment toward goblet cells to suppress inflammatory bowel disease. [PDF]

open access: yesNat Commun
Lin Q   +13 more
europepmc   +1 more source

Cystic Fibrosis and Colorectal Cancer Risk: Reprogramming of the Intestinal Epithelial Niche and Cell‐State Plasticity in the CFTR Modulator Era

open access: yesCell Proliferation, EarlyView.
In cystic fibrosis disorder, CFTR dysfunction drives multilayered intestinal niche disruption, including dysbiosis, inflammation, hypoxia, metabolic stress and genotoxic injury, promoting cell‐state plasticity and a pre‐neoplastic ecosystem. CFTR modulators and environmental factors may partially reshape these processes, highlighting opportunities for ...
Bala Umashankar   +5 more
wiley   +1 more source

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